<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17474

Description mediator of RNA polymerase II transcription subunit 25
SequenceMADKKLIVVVEGTAAMGPFWQSFVSDYLEKIIRCFCGNELNGQKPPTSHAELSVVTFYTHGSYCGCLVQRTGWTRDVDIFLQWLSAIPFAGGGFYDAAIAEGLAEALMMFPILQNGNPNQQNVDTQRHCILVAASNPYPLPTPVYRPQLQNLEKNESIEEQTESRTFDAETVAKSFPQCFVSLSVICPKQLPKLKAIYNAGKRNPRIGDPPVDNVKNPQFLVLISENFMEARAALSRSGITSLPSNQSPVNVDMAPITSVTGPPPASIPLGNGSIMNRQAITAGNNPPATVKVEPSTVTSMLSGPGFSHIPSVARAASQGVPSLQSSSPSSTSQEMITNNDNVQDLKPIVSGVTQPLRPVGPAPANVNILNNLSQARQVMNSAALTGGSSIGLQSMGQTPISMHMSNMISSGMATSVPAAQNVLSSGQSAIPSISGSGPLTGNGQVAQNPGLGSFNSATSNASGNSNLGISQPMGNLQGGVSMGQSGPGMNQGNLSGVQMAQSGIGMNQNMMSGLGPSVVSSGTGTMIPTPGMPQQVQSGMQSLGVNNNSATNMPLSQQTSSALQSAQSKYVKVWEGNLSGQRQGQPVFITRLEGYRSASASETLAANWPATMQIVRLISQDHMNNKQYVGKADFLVFRAMNQHGFLSQLQEKKLCAVIQLPSQTLLLSVSDKACRLIGMLFPGDMVVFKPQISSQQQQQQQMQQQQHQQMQPQQHTQLQQQQLQQLQQQQLPQLQQQQQLTQMQQQQIPQLQQQQQLPQMQQQQIPQLQQQQIPQLQQQQPLSQLQPQQQLPQMQQQQPISQLQTQQQLPQLQQLQQQLPQQQQMVGTGMGQAYVQGPGRSQLVSQGQVSSQGQPNMSGGGFMS
Length865
PositionUnknown
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.04
Grand average of hydropathy-0.394
Instability index62.14
Isoelectric point8.76
Molecular weight93142.43
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IBA:GO_Central
transcription regulator complex	GO:0005667	IBA:GO_Central

GO - Biological Function
DNA binding	GO:0003677	IEA:EnsemblPlants

GO - Biological Process
defense response to fungus	GO:0050832	IEA:EnsemblPlants
jasmonic acid mediated signaling pathway	GO:0009867	IEA:EnsemblPlants
positive regulation of defense response	GO:0031349	IEA:EnsemblPlants
positive regulation of flower development	GO:0009911	IEA:EnsemblPlants
positive regulation of transcription by RNA polymerase II	GO:0045944	IBA:GO_Central
red, far-red light phototransduction	GO:0009585	IEA:EnsemblPlants
response to far red light	GO:0010218	IEA:EnsemblPlants
response to red light	GO:0010114	IEA:EnsemblPlants
trichome branching	GO:0010091	IEA:EnsemblPlants
trichome papilla formation	GO:1905499	IEA:EnsemblPlants









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17474
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     107.94|      15|      15|     736|     750|       1
---------------------------------------------------------------------------
  690-  704 (26.41/ 6.73)	KPQIS..SQQQQQQQMQ
  729-  745 (27.19/ 7.19)	QQQLPqlQQQQQLTQMQ
  746-  762 (28.66/ 8.08)	QQQIPqlQQQQQLPQMQ
  771-  787 (25.67/ 6.28)	QQQIPqlQQQQPLSQLQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     336.80|      68|      83|     417|     497|       4
---------------------------------------------------------------------------
  240-  292 (61.48/19.15)	..ITSLPSN.......QSP.....VNV.DMAPITSVTGPP...P.......ASIPlGNGSI....M.NRQAI..TAGNN..............PP................ATVK.
  296-  361 (45.54/12.35)	......STV.......TSM.....LSGpGFSHIPSVARA......ASQG....VP.SLQSS....SpSSTSQemITNNDNVqdlkpivsGVTQPL................RPVG.
  362-  408 (43.41/11.44)	......PAP.......ANVnilnnLSQ.ARQ....VMNSA...ALTGGS..................SIGLQ..SMGQT..........PISMHM................SNM..
  412-  479 (122.12/45.04)	GMATSVPAA.......QNV.....LSS.GQSAIPSISGSG...PLTGNGQVAQNP.GLGSF....N.SATSN..ASGNSNL........GISQPM................GNLQG
  493-  581 (64.26/20.34)	GNLSGVQMAqsgigmnQNM.....MSGlGPSVVSS..GTGtmiPTPGMPQQVQ.S.GMQSLgvnnN.SATN.........M........PLSQQTssalqsaqskyvkvweGNLSG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.03|      15|      18|     646|     662|      13
---------------------------------------------------------------------------
  646-  662 (17.83/18.74)	FLSqLQEKKlCAVIQL..P
  667-  683 (22.20/12.13)	LLS.VSDKA.CRLIGMlfP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17474 with Med25 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GMNQNMMSGLGPSVVSSGTGTMIPTPGMPQQVQSGMQSLGVNNNSATNMPLSQQT
2) GTGMGQAYVQGPGRSQLVSQGQVSSQGQPNMSGGGFMS
3) LSRSGITSLPSNQSPVNVDMAPITSVTGPPPASIPLGNGSIMNRQAITAGNNPPATVKVEPSTVTSMLSGP
4) LSSGQSAIPSISGSGPLTGNGQVAQNPGLGSFNSATSNASGNSNLGISQPMGNLQGGVSMGQSGPGMNQGNLSGVQMAQS
5) PSVARAASQGVPSLQSSSPSSTSQEMITNNDNVQDLKPIVSGVTQPLR
506
828
235
424
311
560
865
305
503
358










Molecular Recognition Features






MoRF SequenceStartStop




NANANA