<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17464

Description pre-mRNA-processing protein 40A-like isoform X1
SequenceMAGNSQSSGSQPLQHPAVGSLGPQSFGSSLSMQFRSVVPTHQGQQFGPSASQQFRPLGQGFPSNPGMPAGQNQPYQFSQPIQQLHSRPNQPGHATPPSQAVQMPYVQTNRPLASVPLQSQQSAPPLTNHMPGLAGSGMPISSSYMFAPSSFGQPQNSINTLPQFQPMSQMHAPAVPVAGQPWMSSVNQSVAPVTAVQQAGQHPSVSSSTDSAVNTPSSSQQLSSDWQEHTSGDGRRYYYNKRTKQSVWEKPAELMTPVEKADASTVWKEYTSPEGRKYYYNKVTKESKWTIPEELKLAREQAEKSASQGSQSETSVSSHAPDAAAVSVETSVATVSVVSSTTLTLAGVALSPVPVTPVVTDSNPSPVAISGPSVVSGAQPVLSTSAAGFQHQALAPPPPSAVSASTGVPAASTNANSSSMSHFETTASQEFPGSIDGASAQDIEEAKKGMTVAGKVNVTALEEKTLDDEPLLYASKLEAKNAFKALLESVNVQSDWTWEQAMKEIINDKRYGALKTLGERKQAFNEYLGQRKKLEAEERRMRQIKAREEFTKMLEESKELTSSTRWSKAVSMFENDERFKAVERTRDREDLFESYMVELERKEKEKAAEEHRWNVAEYRKFLESCNLIKAHTQWRKVQDRLEDDERCSRLEKLDRLLIFQDYIRDLEKEEEEQKKIQKEQLRRTERKNRDELRKLMEGHAAAGILTAKTHWRDYCLKIKDLPQYQAVASNVSGSTPKDLFEDIAEELEKQYHDDKTRIKDAMKLGKFTLLSTWTFDDFKAAILEDVGSPLISDINLKFVFEELLERAKEKVEKEARKRQRLADDFTKLLYTFKEITASCNWEDCKPLFEESEEYRSIGEESLRREIFEEYIGQLQEKVKEKERKREEEKAKKEKEREEKEKRKEKERKEKDREREREKGKERSKKDETDGENADVIDSHSYKEDKKREKDRDRKHRKRHQTATDDVSSDKDEKEESKKSRRHGSDRKKSRKHAYSPESDSENRHKRHKREHRDGSRRNSGYEELEDGELGEDGEIQ
Length1036
PositionUnknown
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.07
Grand average of hydropathy-1.030
Instability index58.72
Isoelectric point6.46
Molecular weight117324.05
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17464
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.58|      16|      17|     893|     909|       1
---------------------------------------------------------------------------
  909-  925 (20.13/ 6.09)	EkDRER.EREKGKERSKK
  993- 1009 (17.45/ 7.71)	A.YSPEsDSENRHKRHKR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     508.47|      64|      65|     549|     612|       2
---------------------------------------------------------------------------
  483-  540 (77.85/51.71)	.F.KALLESVN...VQSDWTWEQAMKEIINDKRYGA..LK...TLG.....................ER..K..QA.....FNEYLG...QR..K.KL.E..AEERR
  549-  612 (107.48/74.79)	EFTKMLEESKE...LTSSTRWSKAVSMFENDERFKA..VE...RTR.....................DR..E..DL.....FESYMVEL.ER..K.EK.EKAAEEHR
  617-  674 (86.36/58.34)	EYRKFLESCNL...IKAHTQWRKVQDRLEDDERCSR..LE...KL......................DR..L..LI.....FQDYIRDL.EK..E.E......EEQK
  691-  757 (74.76/49.30)	ELRKLMEGHAAagiLTAKTHWRDYCLKIKDLPQYQA..VAsnvSGS.....................TP..K..DL.....FEDIAEEL.EK..Q.YH.D...DKTR
  766-  819 (38.36/20.96)	KFTL..........L.ST..WT.....F..DD.FKAaiLE...DVG.....................SPliS..DInlkfvFE....ELlER.aK.EKvEKEARKRQ
  824-  889 (90.69/61.71)	DFTKLLYTFKE...ITASCNWEDCKPLFEESEEYRS..IG...EES.....................LR..R..EI.....FEEYIGQL.QEkvK.EK.ERKREEEK
  893-  956 (32.97/16.76)	E..K........................EREEKEKR..KE...KERkekdrererekgkerskkdetDG..EnaDV.....IDSHSYKE.DK..KrEK.DRD.RKHR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     152.77|      39|      40|     226|     264|       3
---------------------------------------------------------------------------
  226-  264 (77.41/45.43)	WQEHTSGDGRRYYYNKRTKQSVWEKPAELMTPVEKADAS
  267-  305 (75.37/44.04)	WKEYTSPEGRKYYYNKVTKESKWTIPEELKLAREQAEKS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     182.14|      25|      25|      47|      71|       4
---------------------------------------------------------------------------
   22-   44 (24.41/10.28)	GPqsfgsSLSMQFRS.V...VP..THQ.....G....Q
   47-   71 (51.17/30.32)	GP.....SASQQFRP.LGQGFP..SNP.....GMPAGQ
   74-   93 (36.03/18.99)	PY.....QFSQ...P.I.QQLH..SRP.....NQP.GH
   96-  107 (22.16/ 8.59)	PP.....SQAVQ.....................MPYVQ
  115-  139 (23.85/ 9.86)	VP.....LQSQQSAPpLTNHMPglAGS.....GMP...
  158-  181 (24.52/10.36)	IN.....TLP.QFQP.MSQ.MH..A.PavpvaGQP...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.19|      11|      18|     348|     364|       5
---------------------------------------------------------------------------
  348-  358 (20.85/11.37)	VALSPVPVTPV
  392-  402 (20.34/ 8.26)	QALAPPPPSAV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      30.69|       9|      31|     980|     989|       8
---------------------------------------------------------------------------
  980-  989 (12.85/ 9.36)	RRHGSdRKKS
 1011- 1019 (17.84/ 8.17)	HRDGS.RRNS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17464 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAGFQHQALAPPPPSAVSASTGVPAASTNANSSSMSHFETTASQEFPGSIDGASAQDIEEAKKG
2) FGQPQNSINTLPQFQPMSQMHAPAVPVAGQPWMS
3) SSLSMQFRSVVPTHQGQQFGPSASQQFRPLGQGFPSNPGMPAGQNQPYQFSQPIQQLHSRPNQPGHATPPSQAVQMPYVQTNRPLASVPLQSQQSAPPLTNHMPGLAGSGMP
4) TIPEELKLAREQAEKSASQGSQSETSVSSHAPDAAA
5) VKEKERKREEEKAKKEKEREEKEKRKEKERKEKDREREREKGKERSKKDETDGENADVIDSHSYKEDKKREKDRDRKHRKRHQTATDDVSSDKDEKEESKKSRRHGSDRKKSRKHAYSPESDSENRHKRHKREHRDGSRRNSGYEELEDGELGEDGEIQ
6) VNQSVAPVTAVQQAGQHPSVSSSTDSAVNTPSSSQQLSSDWQEHTSGDGRRYYYNKR
386
151
28
290
878
186
449
184
139
325
1036
242










Molecular Recognition Features






MoRF SequenceStartStop




1) EKEESKKSRRH
2) KYYYNK
3) NRHKRHKREHR
4) RKKSRKHAYS
5) SGYEELEDGELGEDGEIQ
972
277
1002
986
1019
982
282
1012
995
1036