<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17463

Description pre-mRNA-processing protein 40A-like isoform X2
SequenceMAGNSQSSGSQPLQHPAVGSLGPQSFGSSLSMQFRSVVPTHQGQQFGPSASQQFRPLGQGFPSNPGMPAGQNQPYQFSQPIQQLHSRPNQPGHATPPSQAVQMPYVQTNRPLASVPLQSQQSAPPLTNHMPGLAGSGMPISSSYMFAPSSFGQPQNSINTLPQFQPMSQMHAPAVPVAGQPWMSSVNQSVAPVTAVQQAGQHPSVSSSTDSAVNTPSSSQQLSSDWQEHTSGDGRRYYYNKRTKQSVWEKPAELMTPVEADASTVWKEYTSPEGRKYYYNKVTKESKWTIPEELKLAREQAEKSASQGSQSETSVSSHAPDAAAVSVETSVATVSVVSSTTLTLAGVALSPVPVTPVVTDSNPSPVAISGPSVVSGAQPVLSTSAAGFQHQALAPPPPSAVSASTGVPAASTNANSSSMSHFETTASQEFPGSIDGASAQDIEEAKKGMTVAGKVNVTALEEKTLDDEPLLYASKLEAKNAFKALLESVNVQSDWTWEQAMKEIINDKRYGALKTLGERKQAFNEYLGQRKKLEAEERRMRQIKAREEFTKMLEESKELTSSTRWSKAVSMFENDERFKAVERTRDREDLFESYMVELERKEKEKAAEEHRWNVAEYRKFLESCNLIKAHTQWRKVQDRLEDDERCSRLEKLDRLLIFQDYIRDLEKEEEEQKKIQKEQLRRTERKNRDELRKLMEGHAAAGILTAKTHWRDYCLKIKDLPQYQAVASNVSGSTPKDLFEDIAEELEKQYHDDKTRIKDAMKLGKFTLLSTWTFDDFKAAILEDVGSPLISDINLKFVFEELLERAKEKVEKEARKRQRLADDFTKLLYTFKEITASCNWEDCKPLFEESEEYRSIGEESLRREIFEEYIGQLQEKVKEKERKREEEKAKKEKEREEKEKRKEKERKEKDREREREKGKERSKKDETDGENADVIDSHSYKEDKKREKDRDRKHRKRHQTATDDVSSDKDEKEESKKSRRHGSDRKKSRKHAYSPESDSENRHKRHKREHRDGSRRNSGYEELEDGELGEDGEIQ
Length1035
PositionUnknown
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.07
Grand average of hydropathy-1.027
Instability index58.77
Isoelectric point6.39
Molecular weight117195.87
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17463
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     187.27|      37|      38|     215|     251|       1
---------------------------------------------------------------------------
   48-   91 (48.81/23.50)	.PSASQQFRPLGQGFPSnpgmpaGQNQPYQFSQPIQQlhSRPNQP
  215-  251 (72.84/38.49)	TPSSSQQLSSDWQEHTS......GDGRRYYYNKRTKQ..SVWEKP
  256-  291 (65.62/33.99)	TPVEADA.STVWKEYTS......PEGRKYYYNKVTKE..SKWTIP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     132.44|      26|      26|     875|     900|       2
---------------------------------------------------------------------------
  875-  900 (39.64/19.02)	EK.VKEKERKREEE.KAKK......EKEREEKEK
  903-  929 (35.86/16.48)	EKeRKEKDRERERE.KGKE......RSKKDETDG
  943-  974 (35.00/15.91)	DK.KREKDRDRKHR.KRHQtatddvSSDKDEKEE
 1002- 1024 (21.94/ 7.14)	....RHKRHKREHRdGSRR......NSGYEELE.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      90.60|      25|      25|     499|     523|       3
---------------------------------------------------------------------------
  499-  523 (43.13/27.80)	QAMKEIINDKRYGALKTLGERKQAF
  538-  558 (26.42/14.17)	RRMRQIKAREEFT..KMLEESKE..
  574-  591 (21.05/ 9.79)	.......NDERFKAVERTRDREDLF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.68|      17|      26|     138|     159|       4
---------------------------------------------------------------------------
   97-  114 (24.76/ 6.77)	PSQAVQmPYVQTN.....RPLAS
  148-  169 (26.92/20.63)	PSSFGQ.PQNSINtlpqfQPMSQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     214.75|      58|      65|     737|     801|       5
---------------------------------------------------------------------------
  642-  681 (52.79/34.83)	............DDERCSR.LEK......LDRLLI...........................FQDYIR.......DLEKEEEEQKKIQKEQLR
  701-  762 (67.97/47.23)	AGILTAKTHWR..DYCLKI..KDlpqyqaVASN.VS...................gstpkDLFEDIAE.......ELEKQYHDDKTRIKDAMK
  763-  823 (59.19/55.88)	LGKFTLLSTWTFDDFKAAI.LED......VGSPLISdinlkfvFEE......................llerakeKVEKEARKRQRLADD...
  824-  874 (34.80/20.12)	...FTKL.LYTFKEITASCnWED......C.KPL.........FEEseeyrsigeeslrrEIFEEYIG.......QLQ...............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.06|      18|      20|     172|     189|       6
---------------------------------------------------------------------------
  172-  189 (37.38/19.34)	AP..AVPVAGQ.PWMSSVNQS
  191-  211 (23.69/ 9.90)	APvtAVQQAGQhPSVSSSTDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.19|      14|      19|     312|     325|       7
---------------------------------------------------------------------------
  312-  325 (23.98/12.91)	ETSVSSHAPDAAAV
  355-  368 (22.21/11.41)	TPVVTDSNPSPVAI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.84|      32|      36|     370|     404|       8
---------------------------------------------------------------------------
  370-  404 (51.49/36.95)	G.PSVVSGAQpvlSTSAAGFQHQALAPPPPSAVSAS
  406-  438 (52.36/29.88)	GvPAASTNAN...SSSMSHFETTASQEFPGSIDGAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.81|      16|      20|       9|      27|       9
---------------------------------------------------------------------------
   12-   27 (30.23/23.48)	PLQ.HPAVGSLGPQSFG
   31-   47 (25.58/ 9.97)	SMQfRSVVPTHQGQQFG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17463 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAGFQHQALAPPPPSAVSASTGVPAASTNANSSSMSHFETTASQEFPGSIDGASAQDIEEAKKG
2) FGQPQNSINTLPQFQPMSQMHAPAVPVAGQPWMS
3) SSLSMQFRSVVPTHQGQQFGPSASQQFRPLGQGFPSNPGMPAGQNQPYQFSQPIQQLHSRPNQPGHATPPSQAVQMPYVQTNRPLASVPLQSQQSAPPLTNHMPGLAGSGMP
4) TIPEELKLAREQAEKSASQGSQSETSVSSHAPDAAA
5) VKEKERKREEEKAKKEKEREEKEKRKEKERKEKDREREREKGKERSKKDETDGENADVIDSHSYKEDKKREKDRDRKHRKRHQTATDDVSSDKDEKEESKKSRRHGSDRKKSRKHAYSPESDSENRHKRHKREHRDGSRRNSGYEELEDGELGEDGEIQ
6) VNQSVAPVTAVQQAGQHPSVSSSTDSAVNTPSSSQQLSSDWQEHTSGDGRRYYYNKR
385
151
28
289
877
186
448
184
139
324
1035
242










Molecular Recognition Features






MoRF SequenceStartStop




1) EKEESKKSRRH
2) NRHKRHKREHR
3) RKKSRKHAYS
4) SGYEELEDGELGEDGEIQ
971
1001
985
1018
981
1011
994
1035