<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17446

Description mediator of RNA polymerase II transcription subunit 33A-like
SequenceMSSEMEVSVPTEIWDSVRELTMLAQRKGSDPLLWALQISSNLNSAGVALPSVELADVLVSYICWENNLPCLWKFLEKALMLKIVPPMFVLALLSTRVIPCRHSRPAAYRLYLELLKRHAFTLKYQINGLNYQKVMKSIDDVLHLSQRFGMTVSEPGILVVEFIFSIVWQLLDATLDDEGLLELTLEKRSAWAAKSQEMEIDYHDSYDEKRAEFKERLQNVNTVMAIELIGQFLQNKVTSRIIYLARRNMHTHWVDFIQRLRLLEANSTALRNSKALTPEALNQLTSDTRIVLSRECKTASLQKFHGVMAFGSLSTSAGLCQGASRSALWLPLDLLLEDAMDGYLVNATSAIEIITGLIKTLQAINGTTWHDTFLGLWIAALRLVQRERDPIEGPVPRLDTRLCILLSITTLVIADLIEEEESVSVDETECGATNHWKEKNVTGKHRNDLISSLQMLGDYQGLLTPPQSVVSAANQAAEKAMFFVSGISVGSAYFECIGVKDVPINCSGNMRHLIVEACIARNLLDTSAYLWPGYANGCINQIPHHVPTQAPSWSSFMKGAPLTPLLINALVSTPASSLAELEKIFEIAVKGSDDEKISAATILCGASLIRGWNIQEHTVHFIARLLSPPIPLEHSGSDSHLIGYAPMLNVLIVGIASVDCVHIFSLHGLVPQLACSLMPICEVFGSCVPNGSWTLTNGEEISAHAVFSNAFILLLKLWRFNHPPLEHGVGDTPTVGSQLTPEYLLLLRNSHLVYPGNANKNRNRRRLSAAASSSSPQPVFVDSFPKLKAWYRQHQACIASTLSGLVHGTPVHQIVDGLLNMMFKKINRGSQSLTSISVSSSSSGSGNEDTSLRPKLPAWDILEAVPFVVDAALTACAHGKLSPRELATGLKDLADFLPASLATIVSYFSAEVTRGVWKPVFMNGTDWPSPAANLSNVEEQIKKILATTGVDIPSLAAGGSSPSTLPLPLAAFVSLTITYKIDRASERFLNLAGPALESLAAGCPWPCMPIVASLWTQKAKRWSDFLVFSASRTVFLHNSDAVVQLLKSCFTATLGLNAMPISSSGGVGALLGHGFGSHFCGGISPVAPGILYLRVYRSIRDIVFITEEVVSLLMHSVREIVSSGIPRERLEKLRTSKIGMRYRQVSLAAAMTRVKLAAALGASLVWLSGGLSLVQSLIKETLPSLFISVHRSEQEEGSEGMVAMLGGYALAYFVVLCGAFAWGVDSTSSASKRRPKILGTHLEFLASAVDGKISLGCDWATWRAYVSGFVTLMVGCTPNWVLEVDVDVLKRLSNGLRQWDEEELALALLGIGGVGTMGAAAELIIENDM
Length1329
PositionTail
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.07
Grand average of hydropathy0.191
Instability index39.57
Isoelectric point6.34
Molecular weight144982.05
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17446
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      84.46|      17|     364|     244|     260|       1
---------------------------------------------------------------------------
  244-  260 (31.81/20.14)	LAR.RNMHTHWVDFIQRL
  608-  625 (26.03/15.11)	LIRgWNIQEHTVHFIARL
  632-  648 (26.63/15.64)	LEH.SGSDSHLIGYAPML
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     215.10|      44|     186|     767|     810|       2
---------------------------------------------------------------------------
  702-  741 (38.63/18.01)	.........SAHAVFSNA..FIlLLKLW..RFNHpplEHG.....VGD.TPTVGSQL..TP
  767-  810 (76.38/42.92)	L.SAAASSSSPQPVFVDS..FP.KLKAW..YRQH...QAC.....IAS.TLSGLVHG..TP
  833-  883 (48.10/24.26)	LtSISVSSSSSGSGNEDTslRP.KLPAWdiLEAV...PFV.....VDA.ALTACAHGklSP
  955- 1004 (52.00/26.83)	L.AAGGSSPSTLPLPLAA..FV.SLTIT..YKID...RASerflnLAGpALESLAAG..CP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     127.00|      42|     281|     276|     324|       3
---------------------------------------------------------------------------
  276-  324 (62.67/67.63)	LTPEALNQLTSDTRIVLsrecktASLQKFHGVMAFGS....LSTSAGLCqGAS
  562-  607 (64.33/47.77)	LTPLLINALVSTPASSL......AELEKIFEIAVKGSddekISAATILC.GAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.22|      17|     160|     165|     181|       4
---------------------------------------------------------------------------
  165-  181 (30.49/19.76)	SIVWQLLDATLDD..EGLL
  326-  344 (26.73/16.29)	SALWLPLDLLLEDamDGYL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.60|      17|     166|     489|     507|       5
---------------------------------------------------------------------------
  489-  507 (29.79/24.58)	VGSAYFECI......GVkdVP.INCS
  653-  676 (21.81/10.94)	VGIASVDCVhifslhGL..VPqLACS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.64|      15|     930|      37|      51|      13
---------------------------------------------------------------------------
   37-   51 (25.72/15.80)	QISSNLNSAGVALPS
  940-  954 (25.91/15.97)	QIKKILATTGVDIPS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17446 with Med33 domain of Kingdom Viridiplantae
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