<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17440

Description mediator of RNA polymerase II transcription subunit 36a-like isoform X1
SequenceMRPPRGRGGGGGFRGRGDGGGFRGRGDGGRGRGRGGGGRGGDRGSSMGGRGGRGFGGRGRGGGRGGMKGGSKVMVEPHRHGGVFIAKGKEDAIVTKNLVPGEAVYNEKRISVQNEDGTKVEYRVWNPFRSKLAAAIIGGVDEIWIKPGARVLYLGAASGTTVSHVSDIVGPTGVVYAVEFSHRSGRDLVNMAKKRTNVIPIIEDARHPSKYRMLVGMVDVIFSDVAQPDQARILALNASYFLKAGGHFVISIKANCIDSTQPAEAVFQSEVNKLKQDQFKPFEQVTLEPYERDHACVVGGYRVPKKSKIAA
Length311
PositionUnknown
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.07
Grand average of hydropathy-0.435
Instability index26.61
Isoelectric point10.23
Molecular weight33059.24
Publications
PubMed=27145194

Function

Annotated function
ECO:0000256	
GO - Cellular Component
box C/D RNP complex	GO:0031428	IBA:GO_Central
Cajal body	GO:0015030	IBA:GO_Central
small-subunit processome	GO:0032040	IBA:GO_Central
GO - Biological Function
histone-glutamine methyltransferase activity	GO:1990259	IBA:GO_Central
RNA binding	GO:0003723	IBA:GO_Central
rRNA methyltransferase activity	GO:0008649	IBA:GO_Central
GO - Biological Process
box C/D RNA 3'-end processing	GO:0000494	IBA:GO_Central
histone glutamine methylation	GO:1990258	IBA:GO_Central
rRNA methylation	GO:0031167	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats
>MDP17440
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.50|      15|      18|      24|      41|       1
---------------------------------------------------------------------------
   20-   37 (26.99/ 6.22)	GGfrGRGDGGRGrGRGGG
   40-   56 (28.50/ 8.33)	GGdrGSSMGGRG.GRGFG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.44|      14|      17|     201|     214|       2
---------------------------------------------------------------------------
  201-  214 (25.44/16.74)	IIEDARHPSKYRML
  221-  234 (24.00/15.44)	IFSDVAQPDQARIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.53|      15|      17|      60|      75|       3
---------------------------------------------------------------------------
   60-   74 (29.64/ 9.19)	RGGGRGGMKGGSKVM
   79-   93 (25.89/ 7.31)	RHGGVFIAKGKEDAI
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP17440 with Med36 domain of Kingdom Viridiplantae

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MRPPRGRGGGGGFRGRGDGGGFRGRGDGGRGRGRGGGGRGGDRGSSMGGRGGRGFGGRGRGGGRGGMKGGSKVMVEPHRHG
1
81

Molecular Recognition Features

MoRF SequenceStartStop
1) GGGFRGRGDGGGFRGRGDGGRGRGRGGGGRGGDRGSSMGGRGGRGFGGRG
2) MRPPRGR
10
1
59
7