<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17435

Description U-box domain-containing protein 33-like isoform X2
SequenceMFVGMDVVKPTSPITGVVEDMLYVALGEKVKKNKLLLLWALQNSGGRKIYIILVHRPAKVIPIMGVKFPASKLEKKEVDAYQEIERKEMQNILDEYCQICREMGVEAETLYTEMDRVEKGILQLITKHGISKLVMGAAADKHYSKRMMGLKSKKAIYVRQRAPLSCRIQFICEGRLIYTRQNTTTGSSTSMGSPSEETNISVAPSSSAQVSFCCEGESRTVISSFDGTEELPIPRRRFDEEGSSDECTESSRRYPPDSGYSTCSSSGALDMTRVSSARYEGSVNEREHGNRNDTLFQQAMAEAENGRREALQEAERNGKAEKDAVETMRRARLSERSSAEELKQRKEIEEALAKEREEHGKVKNQLNQVIQDLQVALDRQSSLGNQISEYDKMVKWLELKIASSVELLQTSIKERDEMQVERDQALKEAEALRNKQEEVSSTDMVQCLSDLSFSEIEEATRNFDPSLKVGEGRHGRVYKGILCQTEVAIKKLHYHNSGFQLQVDALSKLKHPNLVMLIGSCPEAQALIFEYLPNGTLEDRLSCKDNTPPLSWQTRVCIATGLCSALIFLHSSKPVSILHGDLTPAKVLLGANFVSKLCDWCPLSQDQSLNKNITRFWSTERKGITFPYLDPEFLFTGELTLKSDVYSFGIILLQLLTGRPPLGIQKEVQYALDAGTLQTVLDPLAGDWPFEQAEQWAHLALRCCEMYRKNRPHLRSDVWTELKQMKVLGGCTHSSQLGYEGYSEPPPYILCPISQEVMQDPHVAADGFTYEAKSLREWFDRGHDTSPMTNLKLEHYHLVPNHALRSAIQEWRQRH
Length815
PositionTail
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.07
Grand average of hydropathy-0.484
Instability index46.72
Isoelectric point6.13
Molecular weight92135.93
Publications
PubMed=27145194

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17435
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.00|      34|      36|     494|     529|       1
---------------------------------------------------------------------------
  494-  529 (53.47/45.02)	YHNSGfQLQvDALS.KLKHPNLVMLIGSCPEA...QALIF
  531-  568 (53.53/35.06)	YLPNG.TLE.DRLScKDNTPPLSWQTRVCIATglcSALIF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.48|      28|      41|     144|     174|       3
---------------------------------------------------------------------------
  144-  174 (47.87/42.68)	SKRMMGLKSKKA.IYVrqrAP.LSCRIQFICEG
  187-  216 (43.61/29.77)	SSTSMGSPSEETnISV...APsSSAQVSFCCEG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.96|      29|      49|     376|     406|       4
---------------------------------------------------------------------------
  376-  406 (41.68/39.69)	ALDRQSSLGNQ...ISEYDkMVKWL.ELKIaSSVE
  425-  457 (39.28/27.06)	ALKEAEALRNKqeeVSSTD.MVQCLsDLSF.SEIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      88.03|      29|      40|     291|     319|       5
---------------------------------------------------------------------------
  291-  319 (49.78/39.31)	RNDTLFQQAMAEAENGRR...EAL.QEAERNGK
  329-  361 (38.25/28.19)	RRARLSERSSAEELKQRKeieEALaKEREEHGK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.47|      33|     487|     247|     285|       6
---------------------------------------------------------------------------
  247-  281 (58.68/32.60)	CTESSR....RY..PPdsGYSTCS.SSGALDMTRVSSA..RYEG
  731-  772 (46.79/15.90)	CTHSSQlgyeGYsePP..PYILCPiSQEVMQDPHVAADgfTYEA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.41|      17|     357|     116|     133|       7
---------------------------------------------------------------------------
  116-  133 (25.49/24.62)	RVEKGILqLITKHGISKL
  476-  492 (30.92/23.80)	RVYKGIL.CQTEVAIKKL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17435 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LDMTRVSSARYEGSVNEREHGNRNDTLFQQAMAEAENGRREALQEAERNGKAEKDAVETMRRARLSERSSAEELKQRKEIEEALAKEREEHGKVKNQ
2) SFDGTEELPIPRRRFDEEGSSDECTESSRRYPPDSGYSTCSSSG
269
224
365
267










Molecular Recognition Features






MoRF SequenceStartStop




1) LPIPRRRF
231
238