<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17434

Description U-box domain-containing protein 33-like isoform X1
SequenceMFVGMDVVKPTSPITGVVEDMLYVALGEKVKKNKLLLLWALQNSGGRKIYIILVHRPAKVIPIMGVKFPASKLEKKEVDAYQEIERKEMQNILDEYCQICREMGVEAETLYTEMDRVEKGILQLITKHGISKLVMGAAADKHYSKRMMGLKSKKAIYVRQRAPLSCRIQFICEGRLIYTRQNTTTGSSTSMGSPSEETNISVAPSSSAQVSFCCEGESRTVISSFDGTEELPIPRRRFDEEGSSDECTESSRRYPPDSGYSTCSSSGALDMTRVSSARYEGSVNEREQHGNRNDTLFQQAMAEAENGRREALQEAERNGKAEKDAVETMRRARLSERSSAEELKQRKEIEEALAKEREEHGKVKNQLNQVIQDLQVALDRQSSLGNQISEYDKMVKWLELKIASSVELLQTSIKERDEMQVERDQALKEAEALRNKQEEVSSTDMVQCLSDLSFSEIEEATRNFDPSLKVGEGRHGRVYKGILCQTEVAIKKLHYHNSGFQLQVDALSKLKHPNLVMLIGSCPEAQALIFEYLPNGTLEDRLSCKDNTPPLSWQTRVCIATGLCSALIFLHSSKPVSILHGDLTPAKVLLGANFVSKLCDWCPLSQDQSLNKNITRFWSTERKGITFPYLDPEFLFTGELTLKSDVYSFGIILLQLLTGRPPLGIQKEVQYALDAGTLQTVLDPLAGDWPFEQAEQWAHLALRCCEMYRKNRPHLRSDVWTELKQMKVLGGCTHSSQLGYEGYSEPPPYILCPISQEVMQDPHVAADGFTYEAKSLREWFDRGHDTSPMTNLKLEHYHLVPNHALRSAIQEWRQRH
Length816
PositionTail
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.07
Grand average of hydropathy-0.488
Instability index47.00
Isoelectric point6.13
Molecular weight92264.06
Publications
PubMed=27145194

Function

Annotated function Functions as an E3 ubiquitin ligase. 
ECO:0000256	ARBA:ARBA00003861
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein kinase activity	GO:0004672	IEA:InterPro
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17434
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.00|      34|      36|     495|     530|       1
---------------------------------------------------------------------------
  495-  530 (53.47/48.61)	YHNSGfQLQvDALS.KLKHPNLVMLIGSCPEA...QALIF
  532-  569 (53.53/37.84)	YLPNG.TLE.DRLScKDNTPPLSWQTRVCIATglcSALIF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.60|      22|      23|     232|     254|       2
---------------------------------------------------------------------------
  212-  232 (19.14/ 6.26)	....FCCEGES...RTVISSfdgTEELP
  234-  255 (41.17/22.16)	PRRRFDEEGSS...DECTES...SRRYP
  256-  279 (26.29/ 8.33)	PDSGYSTCSSSgalDMTRVS...SARY.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      91.91|      26|      40|     292|     320|       3
---------------------------------------------------------------------------
  292-  317 (42.79/22.29)	RNDTLFQQAMAEAEN...GRR...EAL.QEAE..R
  330-  359 (29.45/14.97)	RRARLSERSSAEELK...QRKeieEALaKERE..E
  408-  434 (19.68/ 7.24)	....LLQTSIKERDEmqvERD...QAL.KEAEalR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.41|      20|      23|     138|     160|       4
---------------------------------------------------------------------------
  138-  160 (29.08/30.70)	AAdkhYSKRMMGLKSKKAIYVRQ
  162-  181 (37.33/27.80)	AP...LSCRIQFICEGRLIYTRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.41|      17|     358|     116|     133|       6
---------------------------------------------------------------------------
  116-  133 (25.49/24.53)	RVEKGILqLITKHGISKL
  477-  493 (30.92/23.72)	RVYKGIL.CQTEVAIKKL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17434 with Med32 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) SFDGTEELPIPRRRFDEEGSSDECTESSRRYPPDSGYSTCSSSGALDMTRVSSARYEGSVNEREQHGNRNDTLFQQAMAEAENGRREALQEAERNGKAEKDAVETMRRARLSERSSAEELKQRKEIEEALAKEREEHGKVKNQ
224
366










Molecular Recognition Features






MoRF SequenceStartStop




1) LPIPRRRF
231
238