<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17429

Description mediator of RNA polymerase II transcription subunit 36a-like isoform X1
SequenceMRPPRGRGGGGGGGGGFRGRGDGGFRGRGDGGRGRGRGGGGRGGDRGGAMRGRGGRGAGGRGRGGGRGGMKGGSKVVVEPHRHGGVFIAKGKEDAIVTKNLVPGEAVYNEKRISVQNEDGTKVEYRVWNPFRSKLAAAIIGGVDEIWIKPGARVLYLGAASGTTVSHVSDIVGPTGVVYAVEFSHRSGRDLVNMAKKRTNIIPIIEDARHPSKYRMLVGMVDVIFSDVAQPDQARILALNASYFLKAGGHFVISIKANCIDSTQPAEAVFQSEVNKLKQDQFKPFEQVTLEPYERDHACVVGGYRVPKKSKIAA
Length314
PositionUnknown
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.07
Grand average of hydropathy-0.433
Instability index27.36
Isoelectric point10.29
Molecular weight33189.37
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
box C/D RNP complex	GO:0031428	IBA:GO_Central
Cajal body	GO:0015030	IBA:GO_Central
small-subunit processome	GO:0032040	IBA:GO_Central

GO - Biological Function
histone-glutamine methyltransferase activity	GO:1990259	IBA:GO_Central
RNA binding	GO:0003723	IBA:GO_Central
rRNA methyltransferase activity	GO:0008649	IBA:GO_Central

GO - Biological Process
box C/D RNA 3'-end processing	GO:0000494	IBA:GO_Central
histone glutamine methylation	GO:1990258	IBA:GO_Central
rRNA methylation	GO:0031167	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17429
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.39|      24|      27|      10|      36|       1
---------------------------------------------------------------------------
    5-   32 (45.64/14.85)	RGRGgGGGGGGGFRG...RGDGgfrGRGDGG
   33-   60 (44.75/10.38)	RGRGrGGGGRGGDRGgamRGRG...GRGAGG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.44|      14|      17|     204|     217|       2
---------------------------------------------------------------------------
  204-  217 (25.44/17.98)	IIEDARHPSKYRML
  224-  237 (24.00/16.59)	IFSDVAQPDQARIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.20|      16|      17|      63|      78|       3
---------------------------------------------------------------------------
   63-   78 (29.05/15.21)	RGGGRGGMKGGSKVVV
   82-   97 (28.14/14.45)	RHGGVFIAKGKEDAIV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.58|      15|      24|     140|     156|       4
---------------------------------------------------------------------------
  140-  156 (18.11/18.15)	IGG........VDEIwIKPGArVLY
  157-  179 (19.47/ 8.09)	LGAasgttvshVSDI.VGPTG.VVY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17429 with Med36 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MRPPRGRGGGGGGGGGFRGRGDGGFRGRGDGGRGRGRGGGGRGGDRGGAMRGRGGRGAGGRGRGGGRGGMKGGSKVV
1
77










Molecular Recognition Features






MoRF SequenceStartStop




1) GGGGGFRGRGDGGFRGRGDGGRGRGRGGGGRGGDRGGAMRGRGGRGAGGR
2) MRPPRGRGG
12
1
61
9