<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17424

Description mediator of RNA polymerase II transcription subunit 33A-like isoform X1
SequenceMGSECDLGGFEQVVLETLKRCQQQNESTLVWVMEVAKCIRSLGVALPCLELGQVLVSQLCFDDNNSSLWKFVELALSSGLLYPLHVLSLLTSRILPHRRSQPKAYRLYLELLSRYAFSFNPGKADACKEKITKSVDVALQLSQLYRIRVLELGQAFVLFFFSMIIGLIDSTLDDWGLHMTPTDGPSLVLGSTDHHDMDIDFKGSHNVKGNEHHEKMRTTNSFTAIEVLGKLTESRKAMVILRLVHLNMPVNFSGLLQRLQFLEASELVSPHLNSANQLLAKLSANIQRVMGFEYQLNRSQLSGSLLDIASCKPVSCFHSQFGQSACWAPFDIYMENAMDGKQLPIKSAVDVLTEAIKTLQAFNQASWQETFLALWLSALRLVQRERDPPEGPIPRLEARLCVLLSIVPLAITNVLEDEAKLCHSSTAGATFTGSVESGYGHKMNGKGCASRKDGLISSLQILGHFSGLLCPPLSVTDAANTAARKAASFITNAKNQRDIIRGGSLVDASIKAGGNMRHLIVEACIARNLIDTSAYIWPGYVSAPIISLSDSSSHDKSPWLMFMEGAPLNGSLIDYLIMNPASSLAEIEKLFSIALNGSEEEKSAAAKILCGASLSRGWNIQEHVVRFVVKLLSPPIPPSHTGPGSHLVDDMSMLCALLFGASSIDTVHILSLHGAVPEVAASLMPLCEVFGSLKPASRNKSSKDDEPSIYMVFSFAFLYLLRLWKFYRPPLEQCISERGVAVRGELTLEYLLLLRNRSIASCQVETYSNPNQSEPASGKPIYIDSYPKLRAWYCQNKSCIASTLAGLSSGNPVHQVANKILSMIYWKMTKSAASSGNSSTPTSGSACESPRSTGEDAYQRPVLPAWEVLEAIPFVLEAILTACANGRLSSRDLTTGLRDLVDFLPASLAAIVSYFSAEVTRGIWKPVAMNGKDWPSPAAILPSMESEIKAVLAAVGVDAPSCSTGNSPIMLPLPMAALVSLTITFKLDKSLEYIHSVAGLALEHCASGCPWPSMHIIGSLWAQKIRRWHNFIVVSSSRSIFRQNKEAIAQLLRSCFTSFLGSLNISTSSLSNQSSVNGLLGSTISVGGGGSSVAPGFLFLRSCRTIHNVHYVSDIIVGLVAEYARNLASRWASTDSPRLKSSQASLSIASVRAREVATLGASLLCVTGGVQLVQELFRNTIPTWLISSRKQKLHKVSVVSRIVEGYAMAYLLILSGAIVWGVEAKLTTCAFSRRARAVGVHMDFLAGVLEGNISLGCDPATWKAYLSCLVGLMVRFAPAWIQEVKLETLRKLACGLRGWHECELAISLLERGGTAAIGSVAELLNVIS
Length1328
PositionTail
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.07
Grand average of hydropathy0.166
Instability index46.73
Isoelectric point8.36
Molecular weight144362.41
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of phenylpropanoid metabolic process	GO:2000762	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17424
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.34|      29|      98|      49|      89|       1
---------------------------------------------------------------------------
   50-   89 (43.24/44.17)	ELGQVLVsqLCF.....DDNNSSL..WkfvelalssGL.LYPLHVLSL
  151-  187 (38.10/16.04)	ELGQAFV..LFFfsmiiGLIDSTLddW.........GLhMTPTDGPSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     293.61|      91|      98|     538|     635|       2
---------------------------------------------------------------------------
  465-  532 (83.73/46.42)	.................................FSGLLCPPL...SVTDAANTA.ARKAASFITNAKNQRDIIRGGSLVDASIKAGGNMRHLIVEACIarNLIDT
  538-  634 (142.67/110.88)	PGYVSAPIISLSDssshDKSPW..LMFmeGAP.LNGSLIDYL...IMNPASSLAEIEKLFSIALNGSEEEKSAAAKILCGASLSRGWNIQEHVVRFVV..KLLSP
  637-  701 (67.21/39.19)	PPSHTGPGSHLVD....DMSMLcaLLF..GASsIDTVHILSLhgaVPEVAASLMPLCEVFG.SLKPASRNKS.................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      94.38|      28|      29|     876|     903|       3
---------------------------------------------------------------------------
  876-  901 (37.39/18.11)	...............LEAILTA.......CANGRLSSRDLTTGLRDLV
  902-  927 (28.60/12.22)	DF.........lpasLAAIVS.............YFSAEVTRGIWKPV
  933-  979 (28.39/12.08)	DWpspaailpsmeseIKAVLAAvgvdapsCSTGN.SPIMLPLPMAALV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     276.93|      69|      99|    1157|    1226|       4
---------------------------------------------------------------------------
 1080- 1132 (67.69/44.31)	..LG.STISVGGGGSSVA.......PGFLFlrSCRT..IHNVHYVSDIIVGLVAEY.ARNL..ASRWA.....
 1157- 1226 (112.38/83.99)	ATLGASLLCVTGGVQLVQeLFRNTIPTWLI..SSRKQKLHKVSVVSRIVEGYAMAY.LLILSGAIVWGVEAKL
 1260- 1323 (96.86/67.13)	ATWKAYLSCLVG.......LMVRFAPAWIQ..EVKLETLRKLACGLRGWHECELAIsLLERGGTAAIGSVAEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.20|      21|      31|     762|     782|       6
---------------------------------------------------------------------------
  762-  782 (38.89/23.25)	CQVETYSNPNQSEPASGKPIY
  794-  814 (37.30/21.99)	CQNKSCIASTLAGLSSGNPVH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17424 with Med33 domain of Kingdom Viridiplantae
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