<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17414

Description probable mediator of RNA polymerase II transcription subunit 26b isoform X1
SequenceMAKKPGPLEYWRNYFRTANSDIFDIIDHAIMVAASDCPKEFRLRRDRIAERLFSCRLTRCSGCDRVELAVPGGEEEEEDDDVGGCKSSGFDRGRCEFEAGGSKESKVNSSRDDQGEMNMKPVSTYSYGDAEALTDEIEEESQIVGEVLRIKEILYNSEEEPDSVLSESLRKLQLMALTVDILKATEIGKAVNRLRKHASKQIRHIARTLIDGWKDMVDEWVSATTTIAGAEGTSDSVNPSVVDEEEGLPSPPLDEGVFFATQPTSMELSQFFDGMDDDGNPRDSGEFSKNRDNGRKPAQECQNSTKQKLQMPNVVNVLAKDNKSHQVKKQEVFLKPSKPSNTDYGPGRPLKPSTEQMVNNETKYKQKSDKVAIQKRPAGDQQDKFKCSDEVAVQVKLEATKRKLQERYQQAENAKRQRTIQVMELHDLPKQGLGHRNPHVKPGNHNRHWAHGRR
Length454
PositionUnknown
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.06
Grand average of hydropathy-0.930
Instability index46.77
Isoelectric point5.93
Molecular weight51195.65
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17414
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.84|      17|      26|      59|      75|       1
---------------------------------------------------------------------------
   59-   75 (32.84/25.09)	RCSGCD..RVELAVPGGEE
   86-  104 (27.00/19.23)	KSSGFDrgRCEFEAGGSKE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.75|      11|      19|     334|     344|       2
---------------------------------------------------------------------------
  334-  344 (21.52/13.62)	LKPSK....PSNTDY
  350-  364 (15.23/ 7.60)	LKPSTeqmvNNETKY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.74|      13|      28|     246|     258|       3
---------------------------------------------------------------------------
  246-  258 (24.19/12.67)	EGLPSP..PLDEGVF
  273-  287 (19.55/ 8.97)	DGMDDDgnPRDSGEF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.26|      26|      28|     393|     418|       4
---------------------------------------------------------------------------
  393-  418 (41.35/24.05)	VQV.KL.EATKRKLQERYQQAENAKRQR
  420-  447 (37.91/21.52)	IQVmELhDLPKQGLGHRNPHVKPGNHNR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.21|      19|      19|     131|     149|       5
---------------------------------------------------------------------------
  131-  149 (30.02/17.47)	EALTDEIEEESQIVGEVLR
  152-  170 (31.19/18.39)	EILYNSEEEPDSVLSESLR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17414 with Med26 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) EATKRKLQERYQQAENAKRQRTIQVMELHDLPKQGLGHRNPHVKPGNHNRHWAHGRR
2) HQVKKQEVFLKPSKPSNTDYGPGRPLKPSTEQMVNNETKYKQKSDKVAIQKRPAGDQQDKFKCSDEVA
3) IAGAEGTSDSVNPSVVDEEEGLPSPPLDEGVFFA
4) SQFFDGMDDDGNPRDSGEFSKNRDNGRKPAQECQNSTKQKLQMPNVVNVLAKDN
398
325
227
269
454
392
260
322










Molecular Recognition Features






MoRF SequenceStartStop




1) LEYWRNYFR
2) NHNRHWAHGRR
3) VKKQEVFLK
8
444
327
16
454
335