<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17409

Description pre-mRNA-processing protein 40A-like isoform X1
SequenceMANNPRFSGVQPLQPPIVGSVEPPRSFVAPMSSQFRQVVPAQQSQQFNPVPSQHFYPVGLGAPRMNVGLPHHHALQPQFSQSMQQFPPRPGQPGQPGHATLPSQAIPLPIAQPNLHITSEKPIPQINSQTPNSYSPVLGGPERPLTSSYTFASSSYGQPHTNFSASTQYQFTPQMHAPDISSGRQLGLSSESQGTATVAQYAKQPLVPTTVTSATIIQPNTTRESPTDWIEHTSADGRRYYHNKKTRQSSWEKPLELMTPIEMLTGTWSATLLRGRTCCGYLLLSLATILLEYCRSMSLTSPKLFGLGGREKADASTNWKEYTSPDGRKYYYNKVTKESKWSIPEELKLAREQVEKASFMGTQPDTFEIPLVSTTVPPSVVKAPSGGETSSSPAQGVASSPASEGHDVAAGDLKPPLLSETPASTVVASTTDENANGTQTLLNVAALSDAVPENSEAAVTIASTIHAPMENADNLSAEDVPNSADGAPAKVVEGVDAIEALEEVKKDEIGEKLNDIGLEAKSVDPEPMIYANKLEAKNAFKALLESANVGSDWTWDRAMRVIINDRRYGALKTLGERKQVFNEFLSQRKKQEAEERRIKLKKAREEFKQMLEESSELTSSTRWSKAVSMFENDERFKAVERDRERRDLFDNYLGELKEKERARAEEERKRNVMEYRQFLESCDFIKADSQWRKLQDRLEADERCSRLEKMDRLDIFMEYTHDLEKEEEERRKIQKEELRKVERKNRDEFRKLMEEHVTAGTLTAKTHWRDYCMKVKDLLAYTEVASNTSGSTPKELFQDVLEELEKQYHEDKTRIKDAVKLGKILLSSTWVLEDFKFAISKDFSPPISDVNLKLIFDELLERVREKEEKEAKKRKRLADDFFHLLSSIKEITASSKWEDCKQLFADSREFSSIGEESLCREIFEQYISQLKEQAKEHERKRKEEKAKKEKEREEKEKRKVKQRREKEEGREREKDEEDNIKKQRKRHQSSEDIVDENEKDRSRKSHGSSDHKKSRRHASAPESDDESRHKRHKRDHRNGSRRYGDHEELEDGEFGEDRQSW
Length1061
PositionUnknown
OrganismJuglans regia (English walnut)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> fabids> Fagales> Juglandaceae> Juglans.
Aromaticity0.07
Grand average of hydropathy-0.949
Instability index54.47
Isoelectric point6.26
Molecular weight121035.92
Publications
PubMed=27145194

Function

Annotated function 
GO - Cellular Component
U1 snRNP	GO:0005685	IBA:GO_Central
U2-type prespliceosome	GO:0071004	IBA:GO_Central

GO - Biological Function
RNA binding	GO:0003723	IBA:GO_Central

GO - Biological Process
mRNA cis splicing, via spliceosome	GO:0045292	IEA:InterPro
mRNA splicing, via spliceosome	GO:0000398	IBA:GO_Central









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17409
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.54|      14|      17|     938|     954|       1
---------------------------------------------------------------------------
  950-  968 (15.37/ 7.66)	KEREEkekrkVKQRREKEE
  970-  983 (20.17/ 6.47)	REREK.....DEEDNIKKQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     240.36|      36|      36|      42|      77|       2
---------------------------------------------------------------------------
    4-   37 (26.84/12.54)	......NP...RFSgvQPLQPpiVGsVEPPRSFVA.PMSSQF....RQ
   42-   77 (66.04/43.11)	QQSQQFNP...VPS..QHFYP..VG.LGAPRMNVGLPHHHAL....QP
   81-  113 (58.72/37.40)	QSMQQFPP...RPG..QPGQP..GH.ATLPSQAIPLP...IA....QP
  121-  159 (46.55/27.91)	KPIPQINS...QTP..NSYSP..V..LGGPERPLTSSYTFASssygQP
  166-  205 (42.20/24.52)	STQYQFTPqmhAPD.iSSGRQ..LG.LSSESQGTATVAQYAK....QP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.53|      24|      28|    1002|    1029|       3
---------------------------------------------------------------------------
 1002- 1029 (33.60/26.70)	SrksHgSSDHKK.SRRHASAPESDD....ESRH
 1031- 1059 (33.93/15.70)	R...H.KRDHRNgSRRYGDHEELEDgefgEDRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|      99.22|      16|      17|     889|     904|       5
---------------------------------------------------------------------------
  615-  630 (21.12/11.17)	SELTSSTRWSK..AVSMF
  637-  649 (17.47/ 7.67)	KAVERDRER.....RDLF
  889-  904 (27.54/17.32)	KEITASSKWED..CKQLF
  908-  923 (16.36/ 6.61)	REF..SSIGEEslCREIF
  935-  948 (16.73/ 6.97)	KEHERKRKEEK..AKK..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     135.30|      33|      35|     404|     436|       6
---------------------------------------------------------------------------
  370-  391 (20.99/ 7.58)	.............PLVSTTvPPSVVKAPSGGETSS
  404-  436 (55.39/31.43)	EGHDVAA.GDLKPPLLSET.PASTVVASTTDENAN
  443-  470 (32.85/15.80)	...NVAAlSD.AVPENSE...AAVTIASTIHAPME
  471-  492 (26.06/11.09)	NADNLSA.EDV.PNSADGA.PAKVV..........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     157.15|      40|     163|     672|     713|       7
---------------------------------------------------------------------------
  540-  574 (42.82/24.66)	.FKALLESAN.VGSDWTWDRAMRVIINDRRYGALKTL....
  576-  607 (42.92/21.66)	ERKQVFN..EFL...SQ.RKKQ...EAEERRIKLKKArEEF
  674-  713 (71.41/50.25)	EYRQFLESCDFIKADSQWRKLQDRLEADERCSRLEKM.DRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     152.96|      35|      87|     223|     257|       8
---------------------------------------------------------------------------
  223-  240 (24.83/11.63)	........................RE...SPTDWIEHT.SAD...GRR...Y
  241-  281 (40.96/24.80)	YHNKKTRQSSWEKPLEL...........mTPIEMLTGTwSATllrGRTccgY
  293-  330 (41.01/24.84)	Y....CRSMSLTSP...klfglggREkadASTNWKEYT.SPD...GRK...Y
  331-  361 (46.16/29.04)	YYNKVTKESKWSIPEEL.......KL...A.REQVEKA.SFM...G......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.74|      12|      27|     758|     770|       9
---------------------------------------------------------------------------
  758-  770 (18.83/16.45)	TAGTlTAKTHWRD
  788-  799 (21.92/13.68)	TSGS.TPKELFQD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.00|      18|      29|     800|     826|      10
---------------------------------------------------------------------------
  800-  817 (30.37/ 9.91)	VLEELEKQYHED.KTRIKD
  831-  849 (23.63/16.86)	VLEDFKFAISKDfSPPISD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.73|      20|     205|     650|     670|      11
---------------------------------------------------------------------------
  650-  670 (29.35/25.50)	DNYLGELKEKERARAEEeRKR
  857-  876 (32.37/22.53)	DELLERVREKEEKEAKK.RKR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17409 with Med35 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KEQAKEHERKRKEEKAKKEKEREEKEKRKVKQRREKEEGREREKDEEDNIKKQRKRHQSSEDIVDENEKDRSRKSHGSSDHKKSRRHASAPESDDESRHKRHKRDHRNGSRRYGDHEELEDGEFGEDRQSW
2) NFSASTQYQFTPQMHAPDISSGRQLGLSSESQGT
3) NVGLPHHHALQPQFSQSMQQFPPRPGQPGQPGHATLPSQAIPLPIAQPNLHITSEKPIPQINSQTPNSYSPVLGGPERPLTSSYTFASS
4) PSVVKAPSGGETSSSPAQGVASSPASEGHDVAAGDLKPPLLSETPASTVVASTTDENANGTQTLLNVAALSD
5) SEAAVTIASTIHAPMENADNLSAEDVPNSADGAPA
931
162
66
378
455
1061
195
154
449
489










Molecular Recognition Features






MoRF SequenceStartStop




1) ESRHKRHKRDH
2) HEELEDG
1026
1046
1036
1052