<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17367

Description mediator of RNA polymerase II transcription subunit 23
SequenceMALSMETQLQSIFEDVVKTELIEEAFAGMFMDSPEDERTKLISCLGAFRQYWGTLPQESHEQCVQWIVRFIHSQHSPKRIAFLYDCLAMAVETSLLQPRMVCVALISSDSLEWEKTQLWALLFKLIRKIIGGVDYKGVRDLLKAVLDKIQTIPTTVSSAIVQQLLAAREVVEYILDRNACLLPAYFAVTEIRKLYPEGQLSHWLLGSLISDFVDSFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPTTLRFPLRGMLPFDKDLFEPQTGLLRYVLEQPYSREMVCNMLGLNKQTLNIAQQKQRCPVLEEQLVDLVVYAMERSETEEHFDADIGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKECIPVPDINKPQSTHSFAMTCIWIHLNRKAQNDNSKLQIPIPHSLKLHHEFLQQSLRTKTLGMSDYKIALLCNAYSTNSECFSLPMGVLVETIYGNGTMRTNLPGTTCTASGSVTPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSLALAPALVETYSRLLVYMEIESLGIKGFISQLLPNVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHSLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLNDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIHGTWCKDILQTIMNFTPHNWASHTLSCFPAPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMANENDIITHFSMQGSPPLFLCLLWKMLLESDHINQIGFRVLEGIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVNDFVKENAPEHWLQSDWHSKHMNYHKKYPEKLYFEGLAEQVSPPMQLQQQYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYERHLRDRTNLKRKLVHAILSSLKDNRTPGWCLSETYLKCGMNPREDNVWIPDDTYYCKLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALSVPGKDVGNSLLNVVLKSQPLVPRENITAWMNATGLVITALPEPYWIVLHDRIVSVLSSPALTSETEWGDYPFALLDFTACHQSYSEMNCSYVLALAHAVWHHSSIGQLSLIPKFLSETLKPIVQTEFQLLYVYHLVGPFLQRFQQERTRCMLEIGVAFYEMLQAVDQHCAHLSYMDPVCDFLYHIKYMYTGDSVKEQVEKIIMTLRPAMKLRLRFITHSSMIETSTSAGTSASSAASSSSSSGTPQPPPSSLPSSNAAASPSSSSSSQHTHTPL
Length1402
PositionTail
OrganismAustrofundulus limnaeus
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Cyprinodontiformes> Rivulidae> Austrofundulus.
Aromaticity0.09
Grand average of hydropathy-0.034
Instability index46.09
Isoelectric point6.82
Molecular weight159325.57
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17367
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.63|      17|      18|    1048|    1065|       1
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 1048- 1065 (30.92/20.70)	DNRTPG.WCLSETYLkCGM
 1066- 1083 (30.70/16.06)	NPREDNvWIPDDTYY.CKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.73|      17|      19|     248|     266|       2
---------------------------------------------------------------------------
  248-  266 (26.81/23.06)	DPTT..LRFPLRgmLPFDKDL
  268-  286 (26.92/15.25)	EPQTglLRYVLE..QPYSREM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.49|      16|      18|    1007|    1022|       3
---------------------------------------------------------------------------
 1007- 1022 (32.01/21.75)	YKFHDRPVTYLYNTL.H
 1024- 1040 (23.48/13.79)	YERHLRDRTNLKRKLvH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.95|      15|      18|     420|     434|       4
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  420-  434 (29.01/21.76)	CIPVPDINKPQSTHS
  439-  453 (28.94/21.69)	CIWIHLNRKAQNDNS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     150.79|      48|     718|      34|      92|       6
---------------------------------------------------------------------------
   34-   92 (72.31/71.76)	PEDERTKLISCLG.AFRQyWGTLPQESHeqcvqwIVRFIHSQHSPKriafLYDCL..AMAVE
  761-  811 (78.47/47.78)	PQESRFNLKKNVEeEYRK.WKSMANEND......IITHFSMQGSPP....LFLCLlwKMLLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      31|     351|     360|       7
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  351-  360 (18.69/10.35)	IFFVLFQFAS
  384-  393 (19.45/11.09)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.09|      10|      20|     931|     940|       8
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  931-  940 (19.58/11.07)	SKHMNYHKKY
  954-  963 (19.51/11.01)	SPPMQLQQQY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.15|      11|     301|     596|     606|       9
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  596-  606 (21.86/13.41)	FISQLL...PNVFK
  896-  909 (17.29/ 8.98)	FIIQLLllkPNDFR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.94|      10|      31|    1088|    1097|      10
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 1088- 1097 (19.10/11.28)	VDTMAGKSPG
 1122- 1131 (17.84/10.06)	VELMALSVPG
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     135.45|      44|      79|     455|     501|      11
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  455-  501 (72.82/52.76)	LQIPIPHSLKLHHEF.LQQSLRTKTLGMSDYKIAL.LCNAYstnSECFS
  535-  580 (62.63/37.82)	LPMNLLDSLTVHAKMsLIHSIATRVIKLAHAKSSLaLAPAL...VETYS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17367 with Med23 domain of Kingdom Metazoa
Unable to open file!