<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17363

Description mediator of RNA polymerase II transcription subunit 24 isoform X1
SequenceMKVVNLKQAILQAWKERWSDYQWAINIKKNFPKGATWDYLNFAEALMEQAMIGPSPNPLILSYLKYAICSQMVSYSSVLTAISKFDGFSRELCVTSLLEIMDMFCHRLNCHGKAEECIGLCRALLGVVVWLLHGCAFYCDKLRELGPSASTESILQACQERLHNLMSSTKIRALVHIARLEDQGSWNNIEQAVLKVTESLCNVSNQTLRTKLEESVSLVKSIPLMLSVQCDLPVRASFPSVHAFIMLEGTMNLTGEVQPMVEQLMMIKRMQHIPCPLFVLEIWKACFTGLIESPEGTEELKWTAFTFLKIPQVLLGLKTYPQGDKGQDFMEDVNIAFQYLLKLTPLLDKADQRCNCDCLGMLLQECNKLGLLSDLNTENLTSKRTVDREFAPRLKTAENANIQPNPGLILRAEPTVTNILKTVDADHSKSPEGLLGVLGHMLSGKSLDLLLAAAAATGKLKSFARKFIKLNEFPKHISGEGCELSDEFRWGEFFDVLLLLNADMCLRMFPSFSSLAKSASVRALLFDISFLMLCHVVQTYGSEVVLSDLSPSGETPFFETWLQTCMPEEGKTLNPDHPCFRPEPGKVESLVTLLNNSSEMKLVQVKWHEICLSTPAAILEVLNAWENGVLSVEAVQKITDNIKGKVCSMAICAVAWLVAHVRMLGRDEREKPQTMIRQLVTPHYAENTLQFYTERVVIMSSIMEHMCADVFQQTGAVLRPPVEGQEPIPYRNLLPAKEPIHKALSQQFQTVLRKAWVDSRAFHVFESLLNMGGVFWFTNNLIRELLKETRQEWAIRVVELLYSIFCLDTQQITLTLLGTILPNLLTDSAHWHSLSDPPGKALAKLSVWCALSSYSSHHKGPSSARQRKRQREDIEDYNSLFPLDDTQPSKLMRLLSSNEDEPAALSSPGDRSMNSSLSASQIHTVNMRDPLNRVLANLFLLFSSILSSRMAGPHTQFVQSFIEECVECLEQGSHGSILQFMPFTMVSELVKLPALAKPKAVLAMTDLNLPLGRRVAAKAIASL
Length1023
PositionTail
OrganismAustrofundulus limnaeus
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata> Ovalentaria> Atherinomorphae> Cyprinodontiformes> Rivulidae> Austrofundulus.
Aromaticity0.07
Grand average of hydropathy0.009
Instability index47.43
Isoelectric point6.30
Molecular weight114661.15
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17363
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     168.84|      38|     119|     289|     330|       1
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  289-  326 (64.80/39.67)	GLIE.......................................SPEGTEELKWTA.FTFLKIPQVLLGLKTYPQGDKG
  370-  446 (36.09/11.94)	GLLSdlntenltskrtvdrefaprlktaenaniqpnpglilraEPTVTNILKTVD.ADHSKSPEGLLGVLGHMLSGKS
  450-  476 (28.80/13.76)	.LLA.......................................AAAATGKLKSFA.RKFIK.......LNEFPKH...
  479-  510 (39.15/18.90)	G..E.......................................GCELSDEFRWGEfFDVLLLLNADMCLRMFP.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     224.34|      73|     198|     600|     673|       2
---------------------------------------------------------------------------
  600-  673 (119.00/90.07)	MKLVQVKWHEICLSTPAAILEVLNAWENGVLSVEAV.QKITDNiKGK.VCSMAI.CAVAWLVAHVRMLGRDEREKPQ
  795-  870 (105.34/74.60)	IRVVELLYSIFCLDTQQITLTLLGTILPNLLTDSAHwHSLSDP.PGKaLAKLSVwCALSSYSSHHKGPSSARQRKRQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.59|      20|     198|     136|     159|       3
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  103-  122 (40.29/21.15)	MFCHRLNCHGKA...EECIGLCR
  137-  159 (31.30/25.03)	FYCDKLRELGPSastESILQACQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.19|      20|     716|      37|      65|       4
---------------------------------------------------------------------------
   41-   61 (33.22/36.01)	NFAEAL..MEQAMIGPSPNpLIL
  389-  410 (32.97/ 9.15)	EFAPRLktAENANIQPNPG.LIL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17363 with Med24 domain of Kingdom Metazoa
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