<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17349
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MSVGQRFAADHTTSCFLFAPQLYMLRVSPSMGQVLDMNTTLRHLLFLLEYCMVTGHDWWDVLLHVQPSMVHNLVEKLHEEYMRQNQALQQVLATRIVAVKASLCKLSTATAARACDFHAKLLLIAISSTLKSLLRPHVLNTPDKSPGDRLTEICAKNTDTGEPADQVSLLSRWQSPAHLCVCVCVCVCVC |
Length | 190 |
Position | Tail |
Organism | Austrofundulus limnaeus |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi>
Actinopterygii> Neopterygii> Teleostei> Neoteleostei> Acanthomorphata>
Ovalentaria> Atherinomorphae> Cyprinodontiformes> Rivulidae>
Austrofundulus.
|
Aromaticity | 0.06 |
Grand average of hydropathy | 0.212 |
Instability index | 45.80 |
Isoelectric point | 7.58 |
Molecular weight | 21192.64 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP17349
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 84.17| 23| 26| 2| 24| 1
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2- 24 (42.51/22.72) SVGQRFAADHTTSCFLFAPQLYM
30- 52 (41.66/22.17) SMGQVLDMNTTLRHLLFLLEYCM
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