<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17337

Description Transducin beta like 1 Y-linked
SequenceMQFIDAGGNLGLSGKRALCCYCSSVRQCFKTVFFFQTEGGSNFINTSSITSDEVNFLVYRYLQESGFSHSAFTFGIESHISQSNINGTLVPPAALISILQKGLQYVEAEISINEDGTVFDSCPIESLSLIDAVIPDVVQMRQQAFGEKLTQQQASAAATEASAMAKAATMTPAATVNGEENGAHEISECPMEIDGDVEIPPNKATVLRGHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKDVTSLDWNSDGTLLATGSYDGFTRIWTKNGNLASTLCQHKGPIFALKWNKKGNYILSAGVDKTTIIWDAHTGEAKQQFTFHSAPALDVDWQNNMTFASCSTDMCIHVCRLSCDHPVKTFQGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQDACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVVAFSPDGKYLASGSFDKCVHIWNTQSGSLVHSYQGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK
Length533
PositionTail
OrganismPan troglodytes (Chimpanzee)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Hominidae> Pan.
Aromaticity0.08
Grand average of hydropathy-0.170
Instability index37.97
Isoelectric point5.17
Molecular weight57574.83
Publications
PubMed=16136131

Function

Annotated function
GO - Cellular Component
histone deacetylase complex	GO:0000118	IBA:GO_Central
GO - Biological Function
transcription corepressor activity	GO:0003714	IBA:GO_Central
GO - Biological Process
histone deacetylation	GO:0016575	IBA:GO_Central
regulation of transcription by RNA polymerase II	GO:0006357	IBA:GO_Central

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP17337
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     372.17|      39|      39|     365|     403|       1
---------------------------------------------------------------------------
  201-  240 (40.27/18.77)	....PNKatVLRGHESEVFICAWNPVS..dllA.SGSGDSTARIWNL
  259-  295 (47.51/23.37)	EGGHDVP..S....NKDVTSLDWNSDG..tllA.TGSYDGFTRI.WT
  296-  337 (47.05/23.08)	KNGNLAS..TLCQHKGPIFALKWNKKG...nyIlSAGVDKTTIIWDA
  338-  378 (46.79/22.91)	HTGEAKQ..QFTFHSAPALDVDWQ...nnmtfA.SCSTDMCIHVCRL
  379-  420 (63.69/33.67)	SCDHPVK..TFQGHTNEVNAIKWDPSG..mllA.SCSDDMTLKIWSM
  421-  460 (49.16/24.43)	KQDACVH..DLQAHSKEIYTIKWSPTG....pA.TSNPNSSIMLASA
  461-  490 (39.57/18.33)	SFDSTVV..AF............SPDG..kylA.SGSFDKCVHIWNT
  491-  525 (38.12/17.40)	QSGSLVH..SYQG.TGGIFEVCWNARG.dkvgA.SAS.DGS......
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP17337 with Med16 domain of Kingdom Metazoa

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