<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17254

Description Mediator complex subunit 23
SequenceMETQLQSIFEEVVVSAAAGHPGLRMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQVLYYHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKYQGKKCMFEALAGNKGIQVFFLSANLFGIVWLSDSFSSKFDIKVNFPHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDNILFIFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAAVPPQAMNSGSPAPQSNQVPVSLPVTQ
Length1360
PositionTail
OrganismPapio anubis (Olive baboon)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Cercopithecidae> Cercopithecinae> Papio.
Aromaticity0.10
Grand average of hydropathy0.022
Instability index43.41
Isoelectric point7.96
Molecular weight155325.05
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17254
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     263.49|      83|     620|     333|     444|       1
---------------------------------------------------------------------------
  353-  444 (125.55/95.75)	FPHMVLSLHQklAGRGLIKGRDHLMWvLLQFISGSIQ..KNALADFlpVMKLFDLLYPEKEYI.....PVPDiNKPQsthAFAMTCIWIHLNRKAQNDN
  976- 1065 (137.94/77.21)	FPHRFLELLP..VSKSLETLLDHLGG.LYKFHDRPVTylYNTLHYY..EMHLRDRAFLKRKLVhaiigSLKD.NRPQ...GWCLSDTYLKCAMNAREEN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      70.77|      20|     788|      82|     103|       3
---------------------------------------------------------------------------
   82-  103 (32.32/28.51)	CLAMAVETGllPPRLVCESLIN
  872-  891 (38.46/26.95)	CLAMRSHEG..NEAQVCYFIIQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     124.19|      38|     132|     588|     627|       4
---------------------------------------------------------------------------
  588-  627 (63.29/37.47)	FISQLLPTV..FKSHAWGIlHTL......LEMFsYRMHHIQPHYRVQL
  715-  760 (60.89/29.16)	WCKDILQTImsFTPHNWAS.HTLscfpgpLQAF.FKQNNVPQESRFNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.50|      22|     911|     276|     297|       5
---------------------------------------------------------------------------
  237-  251 (20.19/ 8.47)	.......ICNSWKLDPATLRFP
  256-  274 (26.13/13.24)	LPYDKDLFEPQTALLRYVL...
  276-  297 (41.18/25.33)	QPYSRDMVCNMLGLNKQVLYYH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.83|      23|     716|      44|      73|       7
---------------------------------------------------------------------------
   44-   73 (34.19/44.93)	FRQfWGGLSQESHeqciqwIVKFIHGQHSP
  768-  790 (44.64/30.51)	YRK.WKSMSNEND......IITHFSMQGSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     126.79|      43|      84|     447|     489|       9
---------------------------------------------------------------------------
  447-  489 (75.86/46.51)	LQIPIP..................HSLRLHHEF.LQQSLRNKSLQMNDYK..IALLCNAYSTNS
  509-  572 (50.93/28.89)	MRIPLPgtncmasgsitplpmnllDSLTVHAKMsLIHSIATRVIKLAHAKssVALAPALVETYS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.63|      14|      32|     647|     660|      12
---------------------------------------------------------------------------
  647-  660 (23.32/14.97)	LCVESTALR..LITAL
  680-  695 (17.32/ 9.15)	LSAESEELNraLILTL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17254 with Med23 domain of Kingdom Metazoa
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