Description | Mediator of RNA polymerase II transcription subunit 16 |
Sequence | SCQPKIDHLRRLHLGACPTEECKACTRCGCVTMLKSPNRTTAVKQWEQRWIKNCLCGGLWWRVPLSYP |
Length | 68 |
Position | Tail |
Organism | Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates leucogenys) |
Kingdom | Metazoa |
Lineage | Eukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Hylobatidae> Nomascus. |
Aromaticity | 0.07 |
Grand average of hydropathy | -0.431 |
Instability index | 88.04 |
Isoelectric point | 9.24 |
Molecular weight | 7859.22 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | |
GO - Biological Process |
Binary Interactions |
Repeats | >MDP17204 No repeats found No repeats found |
MoRF Sequence | Start | Stop |
1) SCQPKIDHLRRLHLGA 2) TTAVKQWEQRWIKNCLCGGLWWRVPLSYP | 1 40 | 16 68 |
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