<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17148

Description Mediator complex subunit 23
SequenceMETQLQSIFEEVVKTEVIEEAFPGMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQTLNIAQHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDTMAGKSPGPFPNCDWRFNEFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAAVPPQALNSGSPAPQSNQ
Length1365
PositionTail
OrganismGorilla gorilla gorilla (Western lowland gorilla)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Hominidae> Gorilla.
Aromaticity0.10
Grand average of hydropathy-0.012
Instability index45.44
Isoelectric point7.09
Molecular weight156173.81
Publications
PubMed=22398555

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17148
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.22|      24|      89|    1071|    1098|       1
---------------------------------------------------------------------------
  503-  530 (40.13/22.78)	ETIYGNGIMRIplpgTNCMASGSITPLP
 1071- 1094 (47.09/44.25)	DTYYCRLIGRL....VDTMAGKSPGPFP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.84|      14|      43|     331|     358|       2
---------------------------------------------------------------------------
  331-  354 (19.27/40.07)	GTSQLLWqhlssqliffVLFQFAS
  374-  387 (28.56/11.65)	GRDHLMW..........VLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.73|      28|      43|     607|     635|       3
---------------------------------------------------------------------------
  607-  635 (48.25/32.31)	LHTLLEMFSYRM......HHIQPHYrVQLLSHLHT
  647-  680 (42.48/23.61)	LHLCVESTALRLitalgsSEVQPQF.TRFLSDPKT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     194.41|      47|      49|     200|     248|       5
---------------------------------------------------------------------------
  148-  194 (51.23/29.57)	.IPNTVSSAVVQQLL.AARevIAYILERnaC.LLPAY...FAVTEIRKLYPEG.
  200-  248 (77.08/57.10)	LLGNLVSDFVDTFRP.TAR..INSICGR..CsLLPVVnNSGAICNSWKLDPATL
  252-  294 (66.10/40.28)	LKGLLPYD.KDLFEPqTAL..LRYVLEQ......PY..SRDMVCNMLGLNKQTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     169.19|      41|     372|     930|     970|       7
---------------------------------------------------------------------------
  409-  434 (37.65/22.68)	....YPEKEYI..........PVPDINKPQSTHAFAMTCI...
  930-  970 (79.40/57.11)	YHKKYPEKLYFEG..LAEQVDPPVQIQSPYLPIYFGNVCLRFL
 1305- 1338 (52.14/34.63)	YHMKY....MFTGdsVKEQVEKIICNLKPALKLR.....LRFI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     161.39|      51|     717|      22|      89|       8
---------------------------------------------------------------------------
   29-   89 (84.04/84.82)	TPEDEKTKLISCL.GAFRQF........................WGGLSQESHeqciqwIVKFIHGQHSPKrisfLYDCL..AMAVET
  729-  806 (77.35/41.20)	TPHNWASHTLSCFpGPLQAFfkqnnvpqesrfnlkknveeeyrkWKSMSNEND......IITHFSMQGSPP....LFLCLlwKMLLET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     149.45|      46|     261|     977|    1022|       9
---------------------------------------------------------------------------
  977- 1022 (84.36/50.17)	IHRFLE..LLPVSKSLETLL..DHLGGLY..KFHDRPVTYLYN.TLHYYEMHL
 1233- 1285 (65.09/37.06)	IPKFLTevLLPIVKTEFQLLyvYHLVGPFlqRFQQERTRCMIEiGVAFYDMLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     162.66|      51|     261|     546|     600|      10
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  546-  600 (78.75/62.82)	IHSIATRVIKLAHAKSSValapALVETYSRLLVYMEIESLG...IKGFISQLLPTVFK
  809-  862 (83.91/56.97)	INQIGYRVLERIGARALV....AHVRTFADFLVYEFSTSAGgqqLNKCIEILNDMVWK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17148 with Med23 domain of Kingdom Metazoa
Unable to open file!