<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17142

Description Mediator complex subunit 23
SequenceIVQMETQLQSIFEEVVVSVAAGHPGLRMFMDTPEDEKTKLISCLGAFRQFWGGLSQESHEQCIQWIVKFIHGQHSPKRISFLYDCLAMAVETGLLPPRLVCESLINSDTLEWERTQLWALTFKLVRKIIGGVDYKGVRDLLKVILEKILTIPNTVSSAVVQQLLAAREVIAYILERNACLLPAYFAVTEIRKLYPEGKLPHWLLGNLVSDFVDTFRPTARINSICGRCSLLPVVNNSGAICNSWKLDPATLRFPLKGLLPYDKDLFEPQTALLRYVLEQPYSRDMVCNMLGLNKQVLYYHKQRCPVLEDQLVDLVVYAMERSETEEKFDDGGTSQLLWQHLSSQLIFFVLFQFASFPHMVLSLHQKLAGRGLIKGRDHLMWVLLQFISGSIQKNALADFLPVMKLFDLLYPEKEYIPVPDINKPQSTHAFAMTCIWIHLNRKAQNDNSKLQIPIPHSLRLHHEFLQQSLRNKSLQMNDYKIALLCNAYSTNSECFTLPMGALVETIYGNGIMRIPLPGTNCMASGSITPLPMNLLDSLTVHAKMSLIHSIATRVIKLAHAKSSVALAPALVETYSRLLVYMEIESLGIKGFISQLLPTVFKSHAWGILHTLLEMFSYRMHHIQPHYRVQLLSHLHTLAAVAQTNQNQLHLCVESTALRLITALGSSEVQPQFTRFLSDPKTVLSAESEELNRALILTLARATHVTDFFTGSDSIQGTWCKDILQTIMSFTPHNWASHTLSCFPGPLQAFFKQNNVPQESRFNLKKNVEEEYRKWKSMSNENDIITHFSMQGSPPLFLCLLWKMLLETDHINQIGYRVLERIGARALVAHVRTFADFLVYEFSTSAGGQQLNKCIEILNDMVWKYNIVTLDRLILCLAMRSHEGNEAQVCYFIIQLLLLKPNDFRNRVSDFVKENSPEHWLQNDWHTKHMNYHKKYPEKLYFEGLAEQVDPPVQIQSPYLPIYFGNVCLRFLPVFDIVIHRFLELLPVSKSLETLLDHLGGLYKFHDRPVTYLYNTLHYYEMHLRDRAFLKRKLVHAIIGSLKDNRPQGWCLSDTYLKCAMNAREENPWVPDDTYYCRLIGRLVDNILFIFPNPAAHALHVTCVELMALAVSGKEVGNALLNVVLKSQPLVPRENITAWMNAIGLIITALPEPYWIVLHDRIVSVISSPSLTSETEWVGYPFRLFDFTACHQSYSEMSCSYTLALAHAVWHHSSIGQLSLIPKFLTEVLLPIVKTEFQLLYVYHLVGPFLQRFQQERTRCMIEIGVAFYDMLLNVDQCSTHLNYMDPICDFLYHMKYMFTGDSVKEQVEKIICNLKPALKLRLRFITHISKMEPAAVPPQALNSGSPAPQSNQVPVSLPVTQ
Length1361
PositionTail
OrganismGorilla gorilla gorilla (Western lowland gorilla)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Mammalia> Eutheria> Euarchontoglires> Primates> Haplorrhini> Catarrhini> Hominidae> Gorilla.
Aromaticity0.10
Grand average of hydropathy0.029
Instability index44.79
Isoelectric point7.48
Molecular weight155641.48
Publications
PubMed=22398555

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17142
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.11|      13|      17|    1045|    1060|       1
---------------------------------------------------------------------------
 1045- 1058 (24.76/23.04)	RPQG.WCLSDTYLkC
 1063- 1076 (24.35/ 9.68)	REENpWVPDDTYY.C
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.37|      18|      21|     246|     265|       2
---------------------------------------------------------------------------
  246-  265 (29.66/21.28)	LDP..ATLRFPLKGllPYDKDL
  266-  285 (29.71/15.35)	FEPqtALLRYVLEQ..PYSRDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.34|      17|      21|     901|     918|       3
---------------------------------------------------------------------------
  901-  918 (26.47/22.01)	NDFRNRVSDFVKENsPEH
  922-  938 (34.87/24.17)	NDWHTKHMNYHKKY.PEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.22|      15|      15|    1002|    1016|       5
---------------------------------------------------------------------------
 1002- 1016 (28.53/19.10)	YKFHDRPVTYLYNTL
 1019- 1033 (24.69/15.47)	YEMHLRDRAFLKRKL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.60|      31|     788|     177|     207|       6
---------------------------------------------------------------------------
  177-  207 (57.44/33.46)	NACL..LPAY.FAVTEIRKLYPEGKLPHWLLGNL
  965-  998 (44.16/24.01)	NVCLrfLPVFdIVIHRFLELLPVSKSLETLLDHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     132.09|      42|     621|     565|     704|       7
---------------------------------------------------------------------------
  586-  630 (65.00/176.92)	LGiKGFISQLLPTV..FKSHAWGIlHTL......LEMFsYRMHHIQPHYRVQL
  714-  763 (67.10/ 7.02)	IQ.GTWCKDILQTImsFTPHNWAS.HTLscfpgpLQAF.FKQNNVPQESRFNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.14|      10|      31|     346|     355|       8
---------------------------------------------------------------------------
  346-  355 (18.69/12.01)	IFFVLFQFAS
  379-  388 (19.45/12.85)	LMWVLLQFIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     114.09|      35|     738|      47|      92|       9
---------------------------------------------------------------------------
   47-   92 (51.28/61.73)	FRQfWGGLSQESHeqciqwIVKFIHGQHSPKrisfLYDCL..AMAVET
  771-  807 (62.82/39.93)	YRK.WKSMSNEND......IITHFSMQGSPP....LFLCLlwKMLLET
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      85.35|      29|     622|     664|     704|      12
---------------------------------------------------------------------------
  664-  704 (36.23/47.83)	GSSeVQPQFTRFLSDpktvlsaeseeLNRALILTLARATHV
 1300- 1328 (49.12/31.85)	GDS.VKEQVEKIICN...........LKPALKLRLRFITHI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.57|      12|     827|     399|     410|      13
---------------------------------------------------------------------------
  399-  410 (23.55/15.78)	FLPVMKL.FDLLY
 1228- 1240 (18.02/10.07)	LLPIVKTeFQLLY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17142 with Med23 domain of Kingdom Metazoa
Unable to open file!