<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP17064

Description Cwf15/Cwc15 cell cycle control protein-domain-containing protein
SequenceMTTAHRPTFDPAQGKEALRGPAYHQRLLPAYTHLKTRQQGQGNESESQTRDLRAELLQAEATHFAKKNGVPVDAPAIDNGTPKRQLEDAPPGGDAAGIEEDPEAKRRRILEESRDIDADSDGSEEESSDEESDDDEDESAELMRELEKIKKERLEQKEKEERERAVEEEEKREVDIARGNPLLNAQEFNMKRRWDDDVVFKNQARGTEDKRGKEFVNDLLRSDFHKRFMSKYVHRINTSISQLLQRYENIMATATAENTSHTSTAIETFQLDVESTALVRAAEDILALTRTMKETWLFGKLDTLGEDEADVKRREELERNAVAIQKAIADSGVLKPEGGESGKQ
Length344
PositionHead
OrganismAspergillus candidus
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus.
Aromaticity0.04
Grand average of hydropathy-1.069
Instability index60.94
Isoelectric point4.89
Molecular weight39002.44
Publications









Function






Annotated function

Involved in pre-mRNA splicing.



ECO:0000256	ARBA:ARBA00003777

GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
spliceosomal complex	GO:0005681	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
mRNA splicing, via spliceosome	GO:0000398	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP17064
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     108.95|      27|      27|       8|      34|       1
---------------------------------------------------------------------------
    8-   34 (48.96/26.52)	TFDPAQGKEA.LRGP.........AYHQRLLPA.YTHL
   36-   64 (34.72/17.05)	TRQQGQGNESeSQTR.........DLRAELLQAeATHF
  202-  234 (25.27/10.77)	..NQARGTED.KRGKefvndllrsDFHKRFMSK.YVH.
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.50|      21|      25|      76|     100|       2
---------------------------------------------------------------------------
   76-  100 (31.87/25.40)	AidngTPKRQLEDA.PPGGDAAGIEE
  104-  125 (30.63/15.09)	A....KRRRILEESrDIDADSDGSEE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      49.99|      17|      25|     253|     269|       3
---------------------------------------------------------------------------
  253-  269 (29.40/20.84)	TA...TAEN.TSHTSTAIETF
  276-  296 (20.59/12.51)	TAlvrAAEDiLALTRTMKETW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP17064 with Med22 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MTTAHRPTFDPAQGKEALRGPAYHQRLLPAYTHLKTRQQGQGNESESQTRDLRAELLQAEATHFAKKNGVPVDAPAIDNGTPKRQLEDAPPGGDAAGIEEDPEAKRRRILEESRDIDADSDGSEEESSDEESDDDEDESAELMRELEKIKKERLEQKEKEERERAVEEEEKREVDIARGNPL
1
182










Molecular Recognition Features






MoRF SequenceStartStop




1) AGIEEDPEAKRRRILEESR
2) GKEALRGPAYHQRLLPAYTHLKTRQQG
96
14
114
40