Description | Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MAGPQDASLEEILWRSPPHVQMMGGYLHSNNILFYFAESPFFDATSNNASLAIQANYNEAFRHFVETREAFEGRLRTMQGLEFVVAYDPLQAAAQTDSQFAHEPSNVWVIRKQMRRKRAGQEDEVVVLATFFVVGDCIYMAPSVASVVGNRILSAVTSLTSLLKTASTLPIFTPAHGHTYLPPAPKPADAGQPGVPSQQSKENTPMPDAENPARVPLVGSQTGNTTSTFQDTRTLAESLNLFLRYEDEYMDENPLVGEPGSFIMSKANDVDRTATAKQAPNTIPTKMGTPLMRVDTPGKGPEKVGTPSSADESRLKKKKGRVGG |
Length | 324 |
Position | Head |
Organism | Aspergillus novofumigatus IBT 16806 |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes> Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus. |
Aromaticity | 0.08 |
Grand average of hydropathy | -0.405 |
Instability index | 48.53 |
Isoelectric point | 5.92 |
Molecular weight | 35334.44 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery.
ECO:0000256 PIRNR:PIRNR013286 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP17025 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 151.57| 47| 67| 166| 216| 1 --------------------------------------------------------------------------- 166- 216 (75.89/50.03) ASTLPIFTpAHGHTYLPPAPKpadAGQPG..VPSQQSKENTPMPDAENPARVP 236- 284 (75.68/38.89) AESLNLFL.RYEDEYMDENPL...VGEPGsfIMSKANDVDRTATAKQAPNTIP --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) EKVGTPSSADESRLKKKKGRVGG 2) LNLFLRYEDE | 302 239 | 324 248 |
© 2021 Shailesh Lab
Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab