<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16968

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMNIQFHVWKITHWSSKTLFCITIQVIPSIAMVETYVRLLLIDPHSLFRPHFTTLTQRSPSILSKPGVSVLLLEILNYRLLPLYRYHGKNKALMYDVTKIISMIKGKRGEHRLFRLAENLCMNLILSIRDFFLVKKELKGPTEFTETLNRMTIISLAITIKTRGIAEVEQMVYLQPLLEQIMATSQHTWSEKTLRYFPPLIRDSLIGRMDKRGQAIQAWQQAETTVIHQCTQLLSPSADPTYSMTYLSHSFPQHRQYLCAGAWVLMNGLPESISSANLARVLREFSPEEVTSNIYTMVDVLLHHIQLELQRGHAAQDLLSKAISGIVFFIWTHELLPLDILLLALIDRDDDPYALRIVISLLDRTELQQRIKMFCASRTSPEHWLNNQPPKRVEIQKALGNHLVWKDRYPPFFDDIAARLVPVIPLIIYRLIENDATDIAERVLALYSSLLIFHPLRFTFVRDILAYFYGHLPSKLIVRILKVLDISKIPLSESFPQYVSSNPPICPPVDYFATLLVGLVNGVISPLNSKSKSETASEPSGISGRPTISKSQASPQSASANNADGQKAFYQNQDPGTYTQLVLETATIEILSLPATASHIVSSLVQIVVNVQPSLIQSTNGLQGLSGGSGQTSGLPTSPSAGGSESSGPNRSAPAPGINATNFVSKSGYSCQQLSCLMIQACGLLLAQLPPEFHLQLYSEASRIIKECWWLTDGMRSIKELDSAVSYALVDPSWASQDNTSTAIGNIVALLHSFFSNLPHEWLESTHTIIKHLRPVTSIGMMRIAFRIMSPLLPRLAFARPLFMKTLALLFNVMADVFGKNSQPATPVDASEIRDLIDFMHHAVMYEGQGGPVQTSSKPKPEILTLCGKVMELLRPDVQHLFTHLQTDPNSSIYAATHPKLAHNPT
Length905
PositionTail
OrganismDendrobium catenatum
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Asparagales> Orchidaceae> Epidendroideae> Malaxideae> Dendrobiinae> Dendrobium.
Aromaticity0.08
Grand average of hydropathy0.035
Instability index45.28
Isoelectric point8.56
Molecular weight101198.20
Publications
PubMed=26754549
PubMed=28902843

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16968
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.46|      30|     321|     375|     404|       1
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  375-  404 (56.69/40.03)	ASRTSPE.HWLNNQPPKRVEIQKALGNHLV...W
  700-  733 (44.78/29.99)	ASRIIKEcWWLTDGMRSIKELDSAVSYALVdpsW
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     142.96|      37|     706|      44|      82|       2
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   44-   82 (58.92/41.45)	HSLFR..PHftTLTQRSPS...ILS..KPGVSVLLLEILNYRLL.PL
  308-  337 (32.59/15.47)	.............LQRGHAaqdLLS..KAISGIVFF.IWTHELL.PL
  751-  791 (51.45/29.66)	HSFFSnlPH..EWLESTHT...IIKhlRPVTSIGMMRI.AFRIMsPL
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     301.24|     101|     435|     138|     247|       3
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  138-  247 (162.28/107.94)	KGPTEFTE.TLNRMTI..ISLAITikTRGIAE..VEQMVYLQPLLEQIMATSQHTWSE....KTLRYFPPlirdslIGRMDKRG.......QAIQAW..........QQAETTVIHQCTQLLSpSADPTYSMTYLS
  572-  698 (138.96/75.40)	QDPGTYTQlVLETATIeiLSLPAT..ASHIVSslVQIVVNVQPSLIQSTNGLQGLSGGsgqtSGLPTSPS......AGGSESSGpnrsapaPGINATnfvsksgyscQQLSCLMIQACGLLLA.QLPPEFHLQLYS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16968 with Med23 domain of Kingdom Viridiplantae
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