<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16957

Description Mediator of RNA polymerase II transcription subunit 17
SequenceMIRRIDFSQVMERDAKKQKSSKEAVGTQAWPWQSLVENLQLAQQELSIILDLISTVEANDAVTVAGMQRPKQLPHESLSDIAVSAATKLQRLRHLGRYFKQSSKSLEQQVTREARFYGSLIRLQQNWKVKRQRIGLSGPGSESFTIDLLDNSTTDLILSSRSLTLSTVRIDRDPAGILTVQLPSKLCRSLSVEFPGSHSRRKQKGFVKGKMLESGLYPQEGKKEVLTDENVNERVKDSHLILREIHQSIFQEQVFDLVNHESYNPSPGVNVIAMREDRLHLSIGQETSVSLCLLPSIEEESTGRVESNNQAQIRENRISSTDSLGLSAVDENFDSYTRNYLNFPDPVSLEIFLQYLFHDDVFLKSKDRRNDGCNFLGHFCMTIAHRIFSRKVLSLLEGLVEGIPYLHLLSHPTWHSRISSWSLSLKVPQSILRSSRRIKPSGSNDLKSGIRSQFNTKVVVNDDQINVSGEGTPGLVGSLRGDYSDSCSINSYGCDLVDLPVAILHQVANQVIDWLHEEALIVGMKVSRDFLCLYFDLEQGETLGLVANVDAEDTHGCISWWLVFDDGSMEEGKLAAEDVEFRNRRFLGHLSLEALYSTLMDLVGFCGSGGSH
Length612
PositionHead
OrganismDendrobium catenatum
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Asparagales> Orchidaceae> Epidendroideae> Malaxideae> Dendrobiinae> Dendrobium.
Aromaticity0.07
Grand average of hydropathy-0.308
Instability index44.98
Isoelectric point5.94
Molecular weight68751.00
Publications
PubMed=26754549
PubMed=28902843

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16957
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.26|      16|      31|     242|     257|       1
---------------------------------------------------------------------------
  242-  257 (29.03/17.72)	LRE..IHQSIFQEQVFDL
  274-  291 (23.23/12.89)	MREdrLHLSIGQETSVSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     130.52|      41|     233|     189|     232|       2
---------------------------------------------------------------------------
  189-  232 (68.51/46.72)	SLSVEFPGS...HSRR.KQKGfvkGKMLESGLYPQEGKKEVLTDENVN
  422-  466 (62.02/35.15)	SLSLKVPQSilrSSRRiKPSG...SNDLKSGIRSQFNTKVVVNDDQIN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     162.52|      53|     238|     292|     350|       3
---------------------------------------------------------------------------
  292-  350 (79.37/77.43)	CLLPSIEEEST.GRVeSNNQAQIRENRIS........STDSLGLSAVDENFdsytRNYlNFPDPVSLE
  532-  593 (83.16/59.78)	CLYFDLEQGETlGLV.ANVDAEDTHGCISwwlvfddgSMEEGKLAAEDVEF....RNR.RFLGHLSLE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16957 with Med17 domain of Kingdom Viridiplantae
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