<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16956

Description Mediator of RNA polymerase II transcription subunit 19a
SequenceMELDQLFQNASYLREPSTIQPFDLDTLGQAFQLQETAPIDLSSADKGIPTSSGKSKESKNKSKKHKKHKEKDKEKDKEHKKHKHRHKDKSKDKDKEKKKEKSGHHDSGGDHSKKHHDKKRKLEGSEDITDAHKHKKSKVEEKFSSRLGISA
Length151
PositionHead
OrganismDendrobium catenatum
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Asparagales> Orchidaceae> Epidendroideae> Malaxideae> Dendrobiinae> Dendrobium.
Aromaticity0.03
Grand average of hydropathy-1.788
Instability index40.88
Isoelectric point9.63
Molecular weight17352.20
Publications
PubMed=26754549
PubMed=28902843

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16956
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.42|      21|      21|      68|      88|       1
---------------------------------------------------------------------------
   68-   88 (39.84/12.20)	HKEKDKEKDKEHKKHKHRHKD
   90-  110 (34.58/ 9.69)	SKDKDKEKKKEKSGHHDSGGD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.32|      13|      20|       2|      21|       2
---------------------------------------------------------------------------
    2-   15 (18.92/31.86)	ELDQLFQnASYLRE
   23-   35 (23.40/11.23)	DLDTLGQ.AFQLQE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16956 with Med19 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MELDQLFQNASYLREPSTIQPFDLDTLGQAFQLQETAPIDLSSADKGIPTSSGKSKESKNKSKKHKKHKEKDKEKDKEHKKHKHRHKDKSKDKDKEKKKEKSGHHDSGGDHSKKHHDKKRKLEGSEDITDAHKHKKSKVEEKFSSRLGISA
1
151










Molecular Recognition Features






MoRF SequenceStartStop




1) KSKESKNKSKKHKKHKEKDKEKDKEHKKHKHRHKDKSKDKDKEKKKEKSGHHDSGGDHSKKHHDKKRKLEGSEDITDAHKHKKSKVEEKFSSRLGI
2) MELDQLFQNASYL
54
1
149
13