<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16932

Description "Transcription elongation factor A (SII), 1"
SequenceMLVLDQSVFKPVSFSGFTIPPQIQAGALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEVTSLAKSLIKSWKKLLDGPSTDKDSEEKKKEPASSSQNSPEAREESSSSSNSSSRKEEGSAPSNSFIPSFPRAPSTSDSVRVKCREMLSAALRTGDDYIAIGADEEELGSQIEEAIFQELKNTDMKYKNRVRSRIANLKDAKNPNLRKNVLCGNIPPDKFAKMTAEEMASDELKEMRKNLTKEAIREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC
Length305
PositionUnknown
OrganismColumba livia (Rock dove)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Columbiformes> Columbidae> Columba.
Aromaticity0.05
Grand average of hydropathy-0.708
Instability index53.22
Isoelectric point8.51
Molecular weight33926.13
Publications
PubMed=23371554

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
translation elongation factor activity	GO:0003746	IEA:UniProtKB-KW
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro
transcription, DNA-templated	GO:0006351	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16932
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.15|      22|      27|      88|     114|       1
---------------------------------------------------------------------------
   81-  103 (32.00/14.25)	DGPSTDKDSEEKKKEPASSSqNS
  108-  129 (36.15/21.32)	EESSSSSNSSSRKEEGSAPS.NS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      78.75|      18|      27|     209|     226|       2
---------------------------------------------------------------------------
  192-  206 (17.77/ 9.92)	...KNRVRSRIANLKDAK
  209-  226 (31.66/22.93)	NLRKNVLCGNIPPDKFAK
  239-  256 (29.31/20.73)	EMRKNLTKEAIREHQMAK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.45|      14|      27|     262|     275|       3
---------------------------------------------------------------------------
  262-  275 (28.18/18.91)	TDLFTCGKC..KKKNC
  290-  305 (25.27/16.25)	TTFVVCNECgnRWKFC
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16932 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LDGPSTDKDSEEKKKEPASSSQNSPEAREESSSSSNSSSRKEEGSAPSNSFIPSFPRAPSTSDSVRVKCRE
80
150










Molecular Recognition Features






MoRF SequenceStartStop




1) LIKSWKKLL
72
80