<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16904

Description Mediator complex subunit 26
SequenceMVAVLEVISSLEKYPITKEALEETRLGRLINEVRKKTSNEELAKRAKKLLRNWQKLIEPVTQSEPVPRGLPNPPGSANGGAHNCKPEAQLSAVAAPXXXXXXXXXXXLNSPKTEKLGNRKRKGEHRDGHQGPPPPKVSKASHEVLQNSSPPPTNGIGGSPENFPSPVDVNVHAGPESSRTELSENDKHNKIPVNAVKPHTSSPGLVKPSSTSSLLKTAVLQQHDKSEETTGPHQPKSPRCSSFSPRSVRHDTFARQHTTYSPKDSMPSPSQRSQFLDTAQVPSPPPSLMQPSTPPMPAKRLEFPQQSAPEVPQPWQEQQVPPDSQHRHPAGTLQPHTAPGCKTSSHPSESLTPHTGLSQDASKMDSDDAASGSDSKKKKRYRPRDYTVNLDGHVIEGGVKPVRLKERKLTFDPMTGQIKPLTQKDPLQVEIPALAEQHRTETEKQEQKPNLQSPFEQTNWKELSRNEIIQSYLNRQSSLLSSSGVQTPGAHYFMSEYLKQEESTRKEARKTHVLAPNSKPTDLPGVTREVTSDDLDRIREHNWPGVNGCYDTQGNWYDWTQCISLDPHGDDGRLNILPYVCLD
Length583
PositionUnknown
OrganismColumba livia (Rock dove)
KingdomMetazoa
LineageEukaryota> Metazoa> Chordata> Craniata> Vertebrata> Euteleostomi> Archelosauria> Archosauria> Dinosauria> Saurischia> Theropoda> Coelurosauria> Aves> Neognathae> Columbiformes> Columbidae> Columba.
Aromaticity0.04
Grand average of hydropathy-0.999
Instability index64.68
Isoelectric point8.76
Molecular weight63317.96
Publications
PubMed=23371554

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16904
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     541.38|     141|     148|     127|     272|       1
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  117-  266 (228.16/98.76)	GNRKRKgehrDGHQGP.PPPkVSKASHEVLQNSSPP...........PTNG.IG....GSPENFPSP.VDVNVHAGPESSRTElsENDKHNKiPVNAVKPHTSSPGlVKPSSTSSLLKTAVLQQH.DKSEETTGPHQPKSPRCSSFSPRSVRHD....TFARQHTTYSPKDSM
  267-  385 (162.17/60.60)	PSPSQRsqflDTAQVPsPPP.......SLMQPSTPP..........mPAKR.LEfpqqSAPE.VPQPwQEQQV..PPDSQHRH..........PAGTLQPHT.APG.CKTSS............H..PSESLT.PHTGLSQDASKMDSDDAASG....SDSKKKKRYRPRD..
  388-  519 (151.05/55.82)	.....................VNLDGH.VIEGGVKPvrlkerkltfdPMTGqI......KPLTQKDP.LQVEIPALAEQHRT...ETEKQEQ......KPNLQSP..FEQTNWKELSRNEIIQSYlNRQSSLLSSSGVQTPGAHYFMSEYLKQEestrKEARKTHVLAP.NSK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16904 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) RNWQKLIEPVTQSEPVPRGLPNPPGSANGGAHNCKPEAQLSAVAAPXXXXXXXXXXXLNSPKTEKLGNRKRKGEHRDGHQGPPPPKVSKASHEVLQNSSPPPTNGIGGSPENFPSPVDVNVHAGPESSRTELSENDKHNKIPVNAVKPHTSSPGLVKPSSTSSLLKTAVLQQHDKSEETTGPHQPKSPRCSSFSPRSVRHDTFARQHTTYSPKDSMPSPSQRSQFLDTAQVPSPPPSLMQPSTPPMPAKRLEFPQQSAPEVPQPWQEQQVPPDSQHRHPAGTLQPHTAPGCKTSSHPSESLTPHTGLSQDASKMDSDDAASGSDSKKKKRYRPRDYTVNLDGHVIEGGVKPVRLKERKLTFDPMTGQIKPLTQKDPLQVEIPALAEQHRTETEKQEQKPNLQSPFEQTNW
2) TRKEARKTHVLAPNSKPTDLPGVTREVTSDDLDRI
51
504
460
538










Molecular Recognition Features






MoRF SequenceStartStop




1) KHREKHKERK
129
138