<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16859
Description |
Mediator of RNA polymerase II transcription subunit 14 |
Sequence | MAAELGQQTVDFSTLVGRAAEESFLSLKELVEKSKSTDQSDTEKKINLLKYLSRTQQRMLKLNVLAKWCQQVPLIQYCQQLTSTLSSHATCFTQAADSLFFMHEGLQQARAPAYDVPSAIQVLLTGNYRRLPKCIEDVGAQGVLNHNEQKPVLKKLDTLVRSKLLEISIPKEFSGVKVSDGAVLLRVDGEFKVLVTLGYRGHLSLWRILHLELLVGEKSGPIKLEESRRHVLGDDLERRMAAAENPFATLYSVLNELCVALTMDTVTRQVQGLRRGRWKDAIRFEFVMDGNSSLAGSSSSQLNQDGEVDSASLRTPGLKIMYWLDFGKGSGASDPASCPSIKIEPGPDLQIKCLHSTFVLDPLTGKEAEFSLDQSCIDVEKLLLRAIFCNRYTRLLEIQKELSKNSQICRSVGDVKLQPLVGELDVNYKKKDGKVSAMEYEGQEVLCVRAYGSSFFALGINIRNGRFLLQSSQNILPPSSLSECEEALNQGSMTAAEVFIRLRTNSILNLFSSTGRFLGLKVYEDNSAAVKIPKNVATDSTMLLLGFPDCGTSYFLLMQLDKEFKPQFKLLETRSNLSGKAPSGDNHVTCIKKIDMDEMQLPEDELNFGLLDSGKLQSFLPNAGGLNQSTEHGLLSDVSLEGSGLATVGTTSSFSSVVDEVFDLEKGTSLPPFSVQNFSSSYNASASQYGSNPPNFQSMKTGSPSPKWEGGMQVSQVNKVSGGGRLYPPSNMSGSVRSVTSLSAGSGRPASAKRISTSKSEQDLASLRSPHSAEVGPYPSMDEDQLRFLTDSSKDTLSGNRSYRMLSPPRTTGTRSPAPSGKLSGPRTAPNGSAPGSVKALSSSPWVTTPVCKILYNNI |
Length | 859 |
Position | Tail |
Organism | Punica granatum (Pomegranate) |
Kingdom | Viridiplantae |
Lineage | Eukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta>
Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae>
rosids> malvids> Myrtales> Lythraceae> Punica.
|
Aromaticity | 0.07 |
Grand average of hydropathy | -0.282 |
Instability index | 43.06 |
Isoelectric point | 8.03 |
Molecular weight | 93716.51 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU365082
|
GO - Cellular Component | mediator complex GO:0016592 IEA:UniProtKB-UniRule
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:UniProtKB-UniRule
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP16859
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
4| 208.04| 49| 54| 658| 707| 4
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658- 687 (35.50/13.48) ................................VDEVFDLEKGTS..L.PPFSVQNFSSSYNASAS
688- 741 (61.70/32.85) QYGSNPPNfQSMKTGSPSPK......weggmqVSQVNKVSGGGR..LyPP...SNMSGSVRSVTS
743- 792 (64.39/30.49) SAGSGRPA..SAKRISTSKS............EQDLASLRSPHSaeV.GPYPSMDEDQLRFLTDS
793- 844 (46.44/20.06) SKDTLSGN.RSYRMLSP.PRttgtrspapsgkLSGPRTAPNGSA.....PGSVKALSSS......
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