<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16829

Description Cyclin-dependent kinase E-1
SequenceMGDGRGIAAASGGGGGANNRPAWLQQYDLVGKIGEGTYGLVFLAKTKLLKSCIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINHADMSLYLAFDYAEHDLYEIIRHHREKLNHSINQYTVKSLLWQLLNGLNYLHSNWIIHRDLKPSNILVMGEGDEQGVVKIADFGLARIYQAPLKPLSENGVVVTIWYRAPELLLGGKHYTSAVDMWAVGCIFAELLTLKPLFQGVEVKGTPNPFQVDQLDKIFKVLGHPTPEKWPTLVNLPHWHNDQQHIQGHKYDNPCLHSYVHLPPKSPAYDLLSKMLEYDPRKRITAAQALEHEYFRIDPLPGRNALVPTQPVEKIVNYPARPVDTSTDFEGTTSIQPPQSVSSGNVVAGSVAASQVVPSRGVPRPIPLVGMQRVPPASMAAFNIASQGGIGALNPGGLPLQRGAAAQAHSQQLRRKDPGMGMQNTGYPQQKRRF
Length473
PositionKinase
OrganismApostasia shenzhenica
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Asparagales> Orchidaceae> Apostasioideae> Apostasia.
Aromaticity0.08
Grand average of hydropathy-0.288
Instability index39.65
Isoelectric point9.21
Molecular weight52215.32
Publications
PubMed=28902843

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IEA:UniProtKB-EC
RNA polymerase II CTD heptapeptide repeat kinase activity	GO:0008353	IEA:UniProtKB-EC

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16829
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      93.90|      30|      42|     288|     329|       2
---------------------------------------------------------------------------
  288-  323 (42.90/52.99)	HKY..DNPcLHSYVHLPPKSPaydlLSKMLEYdPRKRI
  331-  362 (50.99/26.28)	HEYfrIDP.LPGRNALVPTQP....VEKIVNY.PARPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.94|      34|      42|     162|     198|       3
---------------------------------------------------------------------------
  162-  198 (49.30/51.85)	LVMGEGDEQGVVKIADFGLarIYQA..PLKPLSEnGVVV
  207-  242 (56.64/45.09)	LLLGGKHYTSAVDMWAVGC..IFAEllTLKPLFQ.GVEV
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16829 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ALNPGGLPLQRGAAAQAHSQQLRRKDPGMGMQNTGYPQQKRRF
2) VNYPARPVDTSTDFEGTTSIQPPQSVSSGNVVAG
431
355
473
388










Molecular Recognition Features






MoRF SequenceStartStop




1) NTGYPQQKRRF
463
473