<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16821

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMEQSQRASRHVQLHCGRSAVVDLFNLYLGRNSRQKSDDLPLPREASNKMQKRVTAPIGDLPPRNEQFLLDFEQLQVQFQDREQLRTLTESVLIAFVIQCSAHVPQSEFLLFAMRSLCSVGYVKWDSFLPSLLSTISSAEGSFGSGCPTMIGNSSAVISPSITVPNASSSHISNPASPLPLMHGIGSPTQSITDQSSAPTLSPVKPSELVGTNQLLNMTKLNLSVRSTTISYLRQLACKVILNALESNLKPVTHAEIFSHMINWLVNWGQRNSGIDESETAKPWKPERPLLEWMHSCLDVIWKLVDEDKCLVPFYELIRSGLQYLDNIPDDEAFFSIILEIHRRRDMVATHMQMLDQHLHCPSFGTHRFLSQTYANPPGEPIANLRYSPITYPSVLGEPLHGEELAFSIHKGSLDWERALRCLRHALHTTPSPDWWRRVLLVAPCYRQQAQPPTPGAVFSPEMNCEAVIDRTIDLLKLTNSEVQCWQDWLVFADIFFFLMKSGCIDFLDFVNKLASRVASGDQHILRSNHVTWLLAQIIRIEIVMNTLSSDPKKVETTRKIISFHKEDKNPDSSNVSPQSILLDFISSSQTLRIWSFNSSIREYLNSDQLQKGKQIDEWWKQVTKGERMMDFMNIDDRSMGMFWVLSYTMAQPACEAVMNWLNSSGVTEILQGPNVQSNDRMMMMRETYPLSMSLLSGLSINLCLKLVYQLEDAIFLGQVIPSIAMVETYVRLLLIAPHSLFRPHFTTLTQRSPSILSKPGVSLLLLEILNYRLLPLYRYHGKNKALMYDVTKIISMIKGKRGEHRLFRLAENLCMNLILSIRDFFLVKKELKGPTEFTETLNRMTIISLAITIKTRGIAEVEHMLYLQQLLDQIMSTSQHTWSEKTLRYFPPLIRIPLNQRMDKRGEAIQAWQQAETTVINQCNQLLSPSADPNYVLTYLSHSFPQHRQYVCAGAWVLMNGLPESINSAHLGRILREFSPEEVTSNIYTMVDVLLHHIQLELQRGHVAQELLSKAISGLAFFIWTHELLPLDILLLALIDRDDDPYALRIVIGLLDRPELQQRIKMFCSSRISPEHWLNNQPPKRVELQKALGNHLLWKDRYPPFFDDIAARIIPVIPLIIYRLIENDAPDIAERVLALYSSLLIFHPLRFTFVRDILAYFYGHLPSKLIVRILKVLDISKVITIALVVDLNFDIFYFVVYFVVLTRHYSSDSLIRVLSSVCFFKSTYLSTAGLLCYSSIRPGE
Length1244
PositionTail
OrganismApostasia shenzhenica
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Asparagales> Orchidaceae> Apostasioideae> Apostasia.
Aromaticity0.09
Grand average of hydropathy-0.033
Instability index47.68
Isoelectric point7.24
Molecular weight142178.23
Publications
PubMed=28902843

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16821
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     483.64|     116|     181|     201|     325|       1
---------------------------------------------------------------------------
  201-  320 (191.15/112.17)	SPVK.PSELVGTNQLLNMTKLNLSVRSTTISYLRQLACKVILNALESNLKPvthaEIFSHMINWLVNWGQRNSGIDESETAKPWKPERPLLEWMHSCLDVI......WK..LVDEDKCLVPFYELIRSG
  387-  502 (162.91/87.42)	SPITyPSVL.G..EPLHGEELAFSIHKGSLDWERALRC..LRHALHTTPSP....DWWRRVLLVAPCYRQQAQPPTPGAVFSPEMNCEAVIDRTIDLLKLTnsevqcWQdwLVFAD....IFFFLMKSG
  548-  634 (129.57/64.58)	SS.D.PKKVETTRKIISFHKEDKNPDSSNVS.....PQSILLDFISSS..............QTLRIW.SFNSSIREYLNSDQLQKGKQIDEW..............WK..QVTKGERMMDFMNI....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.87|      16|      16|      94|     109|       3
---------------------------------------------------------------------------
   94-  109 (29.38/18.89)	AFVIQCS.AHVPQSEFL
  112-  128 (26.49/16.29)	AMRSLCSvGYVKWDSFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      60.79|      13|      15|     129|     141|       5
---------------------------------------------------------------------------
  129-  141 (21.76/16.24)	PSLLSTISSAEGS
  147-  158 (20.22/14.41)	PTMIGN.SSAVIS
  159-  169 (18.81/12.74)	PSI..TVPNASSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.52|      40|     512|     335|     377|       6
---------------------------------------------------------------------------
  335-  377 (68.35/57.05)	SIILEIHRRRDMVATHM....QMLDQHLhcpSFGTHRFLSQTYAN.PP
  848-  892 (61.17/40.60)	SLAITIKTRGIAEVEHMlylqQLLDQIM...STSQHTWSEKTLRYfPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.03|      13|      18|      31|      44|       8
---------------------------------------------------------------------------
   31-   44 (21.29/11.86)	NSRQKS.....DDLPlPRE
   47-   64 (20.74/ 7.64)	NKMQKRvtapiGDLP.PRN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16821 with Med23 domain of Kingdom Viridiplantae
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