<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16812

Description Mediator of RNA polymerase II transcription subunit 16
SequenceMEIGAEKKGTEEGDRQMDVADGPAPSPATVFRIRLKQPPSNTRYKMRVPELCRNFRLVLFLFLFCGSAVAWCGKLNVIACASETCARIPSSNVSPPFWIPIHILNPERPTECAVFNAKADSPRDYVQFIDWSPRSCPRALLIANFHGRITIWTQPSEGPLHLVRDASFWQCEYEWRQDLAVVTKWLSGTAQCRPLPSNPSSSSNMKSVFEEKFLLQQSPGSARWPNFLCVCSVFSSGLIQLHWAQWPPPQNGEVQKWFATSKGLLGAGPSGIMAADAIITDAGIMHVAGVPLVNPSTVVVWEVTPGPGSGFQTTAKYSTTNSVPPSVNPPCWTGFAPLAAYLFILQEYIIFEEKQGKRQTDREIIDAASLHCSPVSNFSAYVSPEAAAQCAATTTWGSGVTAVAFDPSRGGSVLAVVIVEGQYMSPYDPDEGPSITGWRVQRWESSLQPVVLHPIFGNPASSFGGQPPMQTVWLTRVNKSIPPTDDMRNPQPCTSSSTISDERNSSDSSIERTKRLSFDPYDLPSDVRQLAQIVYSAHAGEVAVAFLRGGVHIFSGTNFSPVDSYHINVGSTIATPAFSSSSCCLASVWHDTSKDRTTLKIIRVLPPAVPSIQAKVSSATWERAIADRFWWSLLCGADWWDVVGCTQSAADDGTVSLNSMIAVLDADFHSLSSSQLRQLYGPSLDRIKCRVLEGTNAQDVRALVLDMQARLLLDMLGKGIESALINPTTLLPDPWHASSETLASIEADRMVVDQALVPSIQAYVDAVLDLASHFITRLRRYASFCRTLASHAVGATSGTNNARSIVGSPSQSSVSPATSQGQLSYSVASASSGSQSGSSNTGGNSQMQAWMQGAIAKISNNADGGSSSVPNPVTGPSPFVPISINTATFPGTPAVRLIGDCHFLHRLCQLLLFCLIFRRRLSPRFMALGVAAKIEEVQASRSGQLVAGAKGLEEGPPGKSLRLGSGNAGQGYTSEEVKVLFLILVDLCRRTAALQHPLPVSQVGSNNIVIRLHYIDGNYTVLPEIVEASLSPHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFGGPWSDPDELVPLDNTPKSKPFGSDTYAFDFAANCYDSSDTPCLWPRKRRLSERDAAFGLKTSVGLGTYLGIMGSRRDVITATWKTGLEGVWYKCVRCLRQTSAFAQPGSVAATNEREAWWIGRWAHACPMCGGTWVRVV
Length1208
PositionTail
OrganismApostasia shenzhenica
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Asparagales> Orchidaceae> Apostasioideae> Apostasia.
Aromaticity0.08
Grand average of hydropathy-0.111
Instability index49.22
Isoelectric point7.25
Molecular weight131165.51
Publications
PubMed=28902843

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16812
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     297.22|      92|     429|     285|     467|       1
---------------------------------------------------------------------------
  366-  467 (139.48/188.68)	DAASLHCSPvSNFSayVSPeAAAQCAATTTWGSGVTAVAFDPS.RGGSVLAVVIVEGQYMSPYDPDEGPSITgwrVQRWESSLQPVVlhPIFGNPAsSFGGQP
  801-  893 (157.74/61.64)	NARSIVGSP.SQSS..VSP.ATSQGQLSYSVASASSGSQSGSSnTGGNSQMQAWMQGAIAKISNNADGGSSS...VPNPVTGPSPFV..PISINTA.TFPGTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.56|      40|     429|     285|     351|       2
---------------------------------------------------------------------------
   25-   64 (70.56/22.27)	PSPATVFRIRLKQPPSNTRYKMRVPELCRNF.RLVLFLFLF
  305-  345 (73.00/65.31)	PGPGSGFQTTAKYSTTNSVPPSVNPPCWTGFaPLAAYLFIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     265.68|      81|     145|     570|     654|       3
---------------------------------------------------------------------------
  570-  654 (136.60/84.68)	GSTIATpAFSSSSCCLASVWHDTSKDRTTLKIIR.VLPPA.VPSIQAKVSSATwerAIADRFWWSLLCGADWWDVVGCTQSAADDGT
  717-  799 (129.08/68.79)	GKGIES.ALINPTTLLPDPWHASSETLASIEADRmVVDQAlVPSIQAYVDAVL...DLASHFITRLRRYASFCRTLASHAVGATSGT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     227.09|      65|     549|     482|     546|       5
---------------------------------------------------------------------------
  482-  546 (111.20/60.32)	PPTDDMRNPQPCTSSSTISDERNSSDSSIERTKRLSF.DPYDLPSDVRQLAQIVYSAHAGEVAVAF
 1032- 1097 (115.89/63.17)	PHMQNMPRPRGADAAGLLLRELELHPPAEEWHRRNMFgGPWSDPDELVPLDNTPKSKPFGSDTYAF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.01|      16|     195|     914|     929|       6
---------------------------------------------------------------------------
  914-  929 (32.64/18.61)	CLIFR.RRLSPRFMALG
 1111- 1127 (29.37/16.04)	CLWPRkRRLSERDAAFG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.91|      19|     941|       4|      24|       7
---------------------------------------------------------------------------
    4-   24 (30.93/26.04)	GAekKGTEEG..DRQMDVADGPA
  948-  968 (28.98/17.46)	GA..KGLEEGppGKSLRLGSGNA
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16812 with Med16 domain of Kingdom Viridiplantae
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