<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16811

Description Mediator of RNA polymerase II transcription subunit 8
SequenceMEVGGGPPSAPDLQQQQQQPASQASAPPAKVERLNSAVQQQLNLESVKTRALGLFKAISRILEDFDAIARTNSVPKWQDILSQFSMVNLELHNIVEDIKKVSKAFVVHPKNVHGDNASILPVMLSSKLLPEMEAEDNARRELLLAGIADLPISTQIEKLKARIDMIGSACEIAEKVIADNRKAYGLGSRQGPTLVPTLDKVQAAKIQEQENQLRAAVNFGEGLRVSVDQRHLPSSLPSHLVDVLTPGDGVQNFGDSGSFPKSTPFSSNTVNPQGGLMQAPGGQLVGRSVPSPSNVTVPANFDNVSTPPLPYANSPRSGANIMNTPSPQQQTQPPQQRQKMMQVPQHQQQLLAQQQLRQTSTAAILGQGSMSQLHDLQGQTQQKFQTIPNQQQMQYSQSLSQQQFQNRQLQSAHIQQNIAQNQMNQGNPLRNHLSQFTGSANNALFNAAQTSPNPQMITNMSAAMQSQSLLPRMQFGLSAGHPQRNLPTQILNDQMFGMGNANPALAMQQQQHGAQVGFGNLPVSSQNIQQTITGLPNPTQNPNFQQQRQQNQQ
Length553
PositionHead
OrganismApostasia shenzhenica
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Asparagales> Orchidaceae> Apostasioideae> Apostasia.
Aromaticity0.04
Grand average of hydropathy-0.584
Instability index58.42
Isoelectric point9.27
Molecular weight60285.11
Publications
PubMed=28902843

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16811
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     240.97|      50|      50|     328|     377|       1
---------------------------------------------------------------------------
  328-  350 (30.23/ 7.17)	...................................................QQ..QTQPPQQRQKMMQVPQHQQQL
  351-  398 (58.39/21.95)	LAQQQL..RQTSTAAI...LGQGSM.SQL..HDLQ.............gqtQQkfQTIPNQQ..QM.QYSQS....
  399-  469 (59.65/22.61)	LSQQQFqnRQLQSAHIqqnIAQNQM.NQG..NPLRnhlsqftgsannalfnAA..QTSPNPQMITNMSAAMQSQSL
  470-  516 (57.55/21.51)	LPRMQF.....GLSAG...HPQRNLpTQIlnDQMF................GM..GNANPAL...AMQQQQHGAQV
  523-  553 (35.14/ 9.75)	VSSQNI..QQT....I...TG............LP..............npTQ..NPNFQQQRQQNQQ........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.77|      27|      32|     153|     183|       2
---------------------------------------------------------------------------
  153-  183 (35.27/30.55)	STQIEKLKARIDMIgSACEIAEKviaDN..RKA
  188-  216 (40.50/22.63)	SRQGPTLVPTLDKV.QAAKIQEQ...ENqlRAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|      85.94|      15|      32|     246|     260|       3
---------------------------------------------------------------------------
  220-  233 (17.53/ 7.87)	.GEGL......RVSVDQRHLP
  246-  260 (30.05/19.52)	PGDGV......QNFGDSGSFP
  272-  292 (19.57/ 9.77)	PQGGLmqapggQLVGRSVPSP
  298-  307 (18.79/ 9.05)	PA..........NF.DNVSTP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16811 with Med8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) MEVGGGPPSAPDLQQQQQQPASQASAPPAKVE
2) QSLLPRMQFGLSAGHPQRNLPTQILNDQMFGMGNANPALAMQQQQHGAQVGFGNLPV
3) SLPSHLVDVLTPGDGVQNFGDSGSFPKSTPFSSNTVNPQGGLMQAPGGQLVGRSVPSPSNVTVPANFDNVSTPPLPYANSPRSGANIMNTPSPQQQTQPPQQRQKMMQVPQHQQQLLAQQQLRQTSTAAILGQGSMSQLHDLQGQTQQKFQTIPNQQQMQYSQSLSQQQFQNRQLQSAHIQQNIAQNQMNQGNPLRNHLSQFTGSANNALFNAAQTSPNPQMITNMSAAMQ
1
467
235
32
523
465










Molecular Recognition Features






MoRF SequenceStartStop




NANANA