<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16804

Description Mediator of RNA polymerase II transcription subunit 15a
SequenceMDSNNWRPAQGEPPTMETPSADWRSQLQPEARQRIVNKIMDTLRRHLPVPVPEGMNELKKIAVRFEEKIYTAAVNQSDYLRKISLKMLSMETKTQQAAPINPQVVSQNSADSGVTAQVNNQGQVMMASQPSGRQQLLSQNLQNNTSTSIQGSSALSASPNISGLSQSPLSNFGQTSNLQNMPGMTLNSANNSVGQGTTPDIYTAQRQMQGRQQQQSLLSQQQQQQSQNSLLYQNQLQPQLMKQKMHNNGLLQAPLQQQQQQQQSLLQANQLQPSQQPIMQMSGGLPSGHSTIQQSQPATIQSAPQSSLQQNQLNSIQQSVPFTRQSQQAQSSMHSQTSLQQQSASMQQQQQQLMAQQANMSNMQNIQQSQLLGQQSIPEMKPQQQQRLPVQQNNNILNMQQSQQLLSQQTMSLHQQPTPQSQTQQQPQLLGSLSNVSNMQSHQRSMQLLQQTKNIAQSQQQIQQPSMALLQSQGQQSHHQSPQQQLMSQFQSQSGQLQQQLTIQQQPNSMQKEMQQRLQAPSALLQSQNAIEQQKQFMSQRGIPEVSSTTSMDSTGQTAQTGVDWQEEVYQKIQAIKEAHFTELQEFHLKISQKLQQHDALMPLAKQTENYEKLKNYKQFIDRTILLLQIPKNSISVALKDKLPQYERQIVSILSSHRRQKVMPSQQQGQQQYQHPGGNVQNIPPHQPSQVLQVQQNDNHANQVQQMSMPGSMSSIPSTASSNMQHGSMPLQNLAAPTTQNMANSVQSASNLDRGQLNSLASLQHGTMGSVQQSGLGSLQNSVSAGQQGNINNLSQSSMNALQPNSSSLQNSSILQQQQHLKQQQQEQMIQSQQLKQQLQQRQMQQQLLQQQQRQQLLQSQQPLQQQLHQQQKPQQASQLPIHQMPQINQMNELNELKARQGSGMKSGLYQQPYPGGQRHNYYHQQLKPGASFPISSAQNLQATSPQISHHSSPQIDQHNLLPSLTKTGTPLQSTGSPFVVPSPSTPIAPSPIPGDSEKQVSAVTTLPNAGQAAHQQSGSVLPQAHSLAVATPGISASPLLAEFSSPDINPPNLLTTKTSASEKPIERLLKAVQSLSHKALGSAISDIGSVVSMVDRIAGSAPGNGSRAAAGEDLVAITKCRLQARNFMSQDGGASSKKMKRNTSAMPLNNVSTAGSVNDNFMQFSTLDSFDFESTATSRAKRHKVEVNHALQEEIRGINQWLIDTVVSISDEDSDSIVTASEGGDGTIIKCSFSAVSLSPSLKAQFSSKQMSPIAPLRLFVPDNYPNCSPILLDKVPVETSDESDDLSIKAKSRFSISLRCLSQPMSLGEMARTWDACARQVIVEYAQQMGGGSFSSTYGTWENCVSA
Length1349
PositionTail
OrganismApostasia shenzhenica
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Asparagales> Orchidaceae> Apostasioideae> Apostasia.
Aromaticity0.03
Grand average of hydropathy-0.740
Instability index79.13
Isoelectric point9.26
Molecular weight148601.42
Publications
PubMed=28902843

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16804
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.39|      25|      27|     817|     843|       1
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  205-  236 (35.37/ 6.62)	QRQMQGRQ.QQQSLLSQQQQQ..QSQnsllyqnQ.L
  836-  864 (31.02/ 8.13)	KQQLQQRQmQQQLLQQQQRQQllQSQ.......QpL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     134.76|      30|      32|     346|     375|       2
---------------------------------------------------------------------------
  346-  375 (61.23/19.65)	MQQQQQQLMAQQANMSNMQNIQQS.QLLGQQ
  422-  451 (36.29/ 7.49)	QTQQQPQLLGSLSNVSNMQSHQRSmQLL.QQ
  479-  505 (37.24/ 7.95)	HQSPQQQLMSQFQSQSG..QLQQ..QLTIQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     986.49|     204|     238|     629|     835|       3
---------------------------------------------------------------------------
   95-  272 (123.73/23.26)	...........................................................QQAA...PI..NP.QV..VSQ.NSADSGVTAQVNNQGQvmMASQPSgrqqLLSQNLQNntstsiqG......S..SAL...S..AS.....................................P...NISGLSQSPlSN.F..GQTSNLQ.............NM.PGMT........................................................LNSANNSVGQG.TTPDI...ytaqrqmqgrqqqqsllsqqqqqqsqNSLlYQN........qlqpQ..LM...KQKMHNNGLLQAPLQQQQQQ........................QQSLLQ....................ANQL..Q
  273-  596 (153.55/31.28)	.PS................QQPIMQ.MS.....GG.....LPS.GHSTIQQSQ.P.ATIQSAP...QSslQQNQL...........NSIQQ.SVPFT..RQS..Q....QAQSSM.H.......S......Q..TSL...QQQSAsmqqqqqqlmaqqanmsnmqniqqsqllgqqsipemkPQQQQRL.PVQQN.NNiLNMQQSQQLL.............SQ.Q..TMSlhqqptpqsqtqqqpqllgslsnvsnmqshqrsmqllqqtkniaqsqqQIQQPSMALLQ...SQG.QQSH.hqspqqqlmsqfqsqsgqlqqqltiqqqpNSM.QKEMQQ...RL....Q..AP...SALLQSQNAIEQQKQFMSQRgipevssttsmdstgqtaqtgvdwQEEVYQkiqaikeahftelqefhlkiSQKL..Q
  630-  835 (341.91/82.79)	IPKNSISVA..LKDKLPQYERQIVSILS.....SHrrqKVMPS.QQQGQQQYQHPGGNVQNIP...PH..QPSQVLQVQQ.NDNHANQVQQMSMPGS..MSSIPS....TASSNMQH.......G......S..MPL...QNLAA.....................................PTTQNMANSVQSA.SN.LDRGQLNSLA.............SL.QHGTMG................................................SVQQSGLGSLQNSVSAG.QQGNI.............................NNL.SQSSMN...AL....Q..PN...SSSLQNSSILQQQQHLKQQQ........................QEQMIQ....................SQQL...
  863- 1043 (183.78/38.79)	.........................................P.lQQQLHQQ.QKPQQASQ.LP...IH..QMPQINQMNElNELKARQGSGMKSGLY..QQPYPG....GQRHNYYH.......QqlkpgaS..FPIssaQNLQA.....................................TSPQ...ISHHSS.PQ.ID..QHNLLP.............SLtKTGT..................................................PLQSTGSPFVVPSPSTPiAPSPI.............................PGD.SEKQVS...AV....TtlPNagqAAHQQSGSVLPQAHSLAVAT........................PG..IS....................ASPLlaE
 1044- 1255 (183.51/39.03)	FSSPDINPPnlLTTKTSASEKPIERLLKavqslSH...KALGS....AISDIGSVVSMVDRIAgsaPG..NGSRA..AAG.EDLVAITKCRLQARNF..MSQDGG....ASSKKMKR.......N......TsaMPL...NNVS.......................................TAGSVNDNFMQF.ST.LDSFDFESTAtsrakrhkvevnhAL.QEEIRG......................................inqwlidtvvSISDEDSDSIVTA.SEG.GDGTI.............................IKC.SFSAVSlspSL....K..AQ...FSSKQMSPI....................................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.88|      15|      24|    1305|    1319|       4
---------------------------------------------------------------------------
 1305- 1319 (30.83/20.57)	QPMSLGEMAR...TWDAC
 1329- 1346 (26.04/16.02)	QQMGGGSFSStygTWENC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.04|      10|      19|       3|      13|       5
---------------------------------------------------------------------------
    3-   13 (16.67/15.30)	SNNWRpAQGEP
   20-   29 (20.36/11.83)	SADWR.SQLQP
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16804 with Med15 domain of Kingdom Viridiplantae
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