<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16796

Description Mediator of RNA polymerase II transcription subunit 19a
SequenceMDPEGKKFGKGPRELTGAVDLISHYKLLGHHDFFCKKSLPPSISDTHYLHNVVGDTEIRKGEGMELDQLFQNAPYFRETTAYIQTFDLQALGQAFQLRETTPIDLPSAEKGIPTIIGKPKESKDKSKKHKKHKDKDKEKDKEHKKHKHRHKDKSKDKDKDKKDKSAHHDFGAEHSKKHHDKKRKLESSEDVTDIHRHKKSKVAVFYFY
Length208
PositionHead
OrganismApostasia shenzhenica
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> Liliopsida> Asparagales> Orchidaceae> Apostasioideae> Apostasia.
Aromaticity0.08
Grand average of hydropathy-1.319
Instability index30.39
Isoelectric point9.46
Molecular weight24170.09
Publications
PubMed=28902843

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16796
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.11|      15|      15|     127|     141|       1
---------------------------------------------------------------------------
  127-  141 (30.36/11.69)	KKHK.K.HKDKDKEKDK
  144-  159 (24.70/ 8.13)	KKHKhR.HKDKSKDKDK
  161-  176 (22.05/ 6.47)	KKDK.SaHHDFGAEHSK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.73|      16|     145|      30|      47|       2
---------------------------------------------------------------------------
   30-   47 (27.85/19.33)	HHDffCKKSLPPS..ISDTH
  178-  195 (24.88/10.96)	HHD..KKRKLESSedVTDIH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.11|      11|      24|      66|      80|       3
---------------------------------------------------------------------------
   66-   80 (16.05/22.86)	LDQLFQnapyFRETT
   91-  101 (21.06/14.10)	LGQAFQ....LRETT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16796 with Med19 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) PSAEKGIPTIIGKPKESKDKSKKHKKHKDKDKEKDKEHKKHKHRHKDKSKDKDKDKKDKSAHHDFGAEHSKKHHDKKRKLESSEDVTDIHR
106
196










Molecular Recognition Features






MoRF SequenceStartStop




1) IHRHKKSKVAV
2) KSKKHKKHKDKDKEKDKEHKKHKHRHKDKSKDKDKDKKDKSAHHDFGAEHSKKHHDKKRKLE
194
125
204
186