<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16774

Description Leucyl-tRNA synthetase
SequenceMNAKEKKEFELKKSMEMKAKIEKLDNMIKMINEITATFNNICDHLSETWKPQEQEVSRMNLAKNEETTLPLPTYDPDYIEKMNDKIMNKMEEFSQLLKLSSVDLEHAQKVEEEWNANQNNQKKPYIKYNPKDEEKIIVDLKEVMQKTSQQVTNTFSKDYKTYFKKCKNEEQRIITELPFLNRTKLYDARTIDNWLAEAKQKSCKVEIDKTDSDNSGRVSTFTVLVNNFLKVYISLKYNDIDGSSLTISRIAFFGCHEKKAILETSDSLEYQRITQLATAKLNELDPINPIPDLLDWIYSYHDLTSKPYLLAIERKWRERWKQLKNRPKNQENKQKFYILAMFPYPSGMLHMGHVRVYTISDTISRFRKMLGHEVIHPMGWDAFGLPAENAAIEHGIHPVDWTVSNIKAMKMQMEKILTDFDWDRELSTCNSDYYKWTQYLFLKLYKNGLAYQKEAVVNWDPIDQTVLANEQVDGEGRSWRSGAKVELRKLKQWFFKITDFAEPLLKDLDKLNEWPDRVKQMQRYWIGKSEGAEFDFIVNLNRKYRETTFLIKVFTSRPDTIFGVRYLAISTDHALVSKDFLQSDVYSKVLKLAEEMKQYLIGANEKKKSTKGINTGLYATHPITGATIPIYVASYVVSDYGTGAVMGVPAHDQRDWNFTKANRIVDEKDIRRVVKPYSAKFIEECEVYTSYGILTSDCGQYAGMSSENAINAIVNDAEKRGYGRSAVQYRLRDWLISRQRYWGAPIPMIHCSRCNVVPVPESELPVILPTNISLTGRGGSPLKYVKDWLNTKCPKCHGPAERDTDTMDTFVDSSWYFMRYTDPNNILLPFSHDKASKYLPIDVYVGGVEHAILHLLYSRFFTKFLYKLGMYKPIHNNTQGRDEPFRQLVTQGMVHAKTFKDPLTGRFLKPEEVDLSNPNEPIQKSTRLAPEISFEKMSKSKYNGIDPEITIEKFKYCSDDLILNMSMMSNEEKETYRLINFTIKELTTIFYDTYSFNTAVSYLIKLTNHLTSISPNVNMSRPVYIYGVKCLVKMMAPMAPSLGEEFWEVLNKGRGTRTIFEESWPKVDNKGLSVEEVTCVVQINGKMRFSLQVPSSILKDNLMVEMLIRKSNNGQKWIEENQTGKKIKRVIHANGGKIVNFVFENNQRKE
Length1150
PositionTail
OrganismRhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194) (Arbuscular mycorrhizal fungus) (Glomus intraradices)
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Glomeromycotina> Glomeromycetes> Glomerales> Glomeraceae> Rhizophagus.
Aromaticity0.11
Grand average of hydropathy-0.540
Instability index33.44
Isoelectric point8.68
Molecular weight133608.74
Publications
PubMed=30271968

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
aminoacyl-tRNA editing activity	GO:0002161	IEA:InterPro
ATP binding	GO:0005524	IEA:UniProtKB-KW
leucine-tRNA ligase activity	GO:0004823	IEA:UniProtKB-EC

GO - Biological Process
leucyl-tRNA aminoacylation	GO:0006429	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16774
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     150.20|      39|      53|      44|      82|       1
---------------------------------------------------------------------------
    1-   24 (25.00/10.52)	................MNAKEKKEFELKKSMEMKAKIEKL
   44-   82 (67.49/41.04)	HLSETWKPQEQEV.SRMNLAKNEETTLPLPTYDPDYIEKM
   98-  136 (57.70/34.01)	KLSSVDLEHAQKVeEEWNANQNNQKK.PYIKYNPKDEEKI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     639.56|     195|     424|     431|     684|       2
---------------------------------------------------------------------------
  272-  429 (191.11/92.46)	....................................................................................RITQLA.........TAKLNELDPINPIPDLLD.....WIySYHDLTSKPYLLAI.....ERK..WRErwkqlknrpknqenkqKFYILA....MF.PYPSGMLHMGHVRVYTIS.DTISR........F...RKMLghEVIHPMGWDAFGlPAENAAIEHGIHPVDWTVSNIKAMKMQM...EKILTDFDWDRELSTC
  431-  649 (294.67/257.99)	SDYYkwTQYLF.LKLYK..................NGLAYQKeavVNWDPIDQTVLANEQVDgegrswrsgakveLRKLKQWFFKITDFA.........EPLLKDLDKLNEWPDRVKqmQrYWI.GKSEGAEFDFIVNL.....NRK..YRE................TTFLIK....VFTSRPDTIFGVRYLAISTDH.ALVSKDF.LQSDVY...SKVL..KLAEEMKQYLIG.ANEKKKSTKGINTGLYATHPITGATIPIyvaSYVVSDYGTGAVMGVP
  858- 1038 (153.77/76.01)	SRFF..TKFLYkLGMYKpihnntqgrdepfrqlvtQGMVHAK...TFKDPLTGRFLKPEEVD.............LSNPNEPIQKSTRLApeisfekmsKSKYNGIDP...........E.ITI.EKFKYCSDDLILNMsmmsnEEKetYRL................INFTIKelttIFYDTYSFNTAVSYLIKLTNHlTSISPNVnMSRPVYiygVKCL.vKMMAPM......................................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      98.34|      25|     435|     660|     684|       4
---------------------------------------------------------------------------
  660-  684 (41.56/30.63)	KANRIVDEKDIRRVVKPYSAKFIEE
 1099- 1120 (39.01/28.25)	KDNLMV.EMLIRK..SNNGQKWIEE
 1123- 1140 (17.77/ 8.37)	......TGKKIKRVIHANGGKIVN.
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16774 with Med27 domain of Kingdom Fungi
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