<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16766

Description Mediator of RNA polymerase II transcription subunit 5
SequenceMFFAYNLVQTRPVMTDDMAVEYLEKLQHIQVSCDHEFYVELWMSALTGLAEECDKTSTGRVQHTLLWKSFVLVKLPSLIEKLELKKSNKFKNGNLLYSEENKYDCHECVINQLFGFKGLINACNQLVEDDIFQAADITVDILRVCLNRKLVRKEFVNRFLELEYEIDGGDTVGLTAGNILDDPSRQIIDHLVSTATTSFLHQESRVETIFKLMSEWSTKLEVAPLATLCRSLMDVPTLLDIIHLYRHPSEFISSLERLCNTWVSKADSKESLLHDYENFGTIFLFLISVIDRYEFHKNIKDVLHDDEGFCYKWLIQSGSTYDIDSLDQEKSIITRLVSTLSDASQEIPEDLIRISPRSLIELSPTIFKEALKKVVTEDIEIAMINLEPLFTHFVKPHMSYALIGVCQSLCDDILFKGKSSISFKVLNRLILEEAFPNSIIKLIGNKLLSIFDIISENGSLPSIEDTENIIRNKIAKIMMVPNWRNTKHPAEKLYYRFKMMFKSIIYGGRHKPSLIYEIFLSENYFNNDINTEYEYITGNGGAANNLFDEFIINPSSWLGPHHLDIELFRNCLEINGPRTFVDLIVEEVLSAGKKGMGIRAAELGASLLTLPIYYTWNEYLHPKTLIKIFFMDFLPSILEKKIDMYTQSYSIGIMTLSILMMIKKDTQNVGGVDVSIDEIVGINNNVDGTNDILMMDAIISEERIGGMEGVGGTKVEIEDFTKFVLSIFKQDRDNADSDNIDSKVIQNGSKKIDDKVKNESEPKLINGPAKGFIDALLIHEDIVPELKSLVNK
Length792
PositionTail
OrganismRhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194) (Arbuscular mycorrhizal fungus) (Glomus intraradices)
KingdomFungi
LineageEukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Glomeromycotina> Glomeromycetes> Glomerales> Glomeraceae> Rhizophagus.
Aromaticity0.09
Grand average of hydropathy-0.072
Instability index38.68
Isoelectric point5.06
Molecular weight90314.99
Publications
PubMed=30271968

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16766
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     135.41|      43|     189|     544|     587|       1
---------------------------------------------------------------------------
  111-  161 (55.72/32.94)	NQLFGfKGLINACNQLVEDDIfqaaDItvDILRVCLNRKLVRkEFVNRFLE
  544-  586 (79.70/56.66)	NNLFD.EFIINPSSWLGPHHL....DI..ELFRNCLEINGPR.TFVDLIVE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     260.04|      87|     115|     163|     257|       2
---------------------------------------------------------------------------
  163-  257 (134.59/114.49)	EYEIDGgdTVGLTAGNILD..DPSRQIID..HLVSTATTSFLHQESRVETIFKLMSEWS..TKLevapLATLCRSLMDVPTllDIIHLY.R.....HPSEFISSLER
  275-  373 (125.45/85.54)	DYENFG..TIFLFLISVIDryEFHKNIKDvlHDDEGFCYKWLIQSGSTYDIDSLDQEKSiiTRL....VSTLSDASQEIPE..DLIRISpRslielSPTIFKEALKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.91|      16|     433|      65|      92|       3
---------------------------------------------------------------------------
   66-   81 (28.72/36.17)	LWKSFVLVKLPSLIEK
  625-  640 (29.19/ 6.77)	LIKIFFMDFLPSILEK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16766 with Med5 domain of Kingdom Fungi
Unable to open file!