<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16765
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MTTLNTTSTTSTLWSHTDTDIERLYYELCYRKAPRRIAWSTQNIIAWSPHPNDNLDTKFSRYCPNVGIYSPCRGIDANGPAWSFINKEYLSLFDRVENYHRFGDVITDLVWNQTGSALASIDQRGKIAIWTMNNFINQWKCICNVNLGESVIEFTWLDSARLYSREHVPQSSGYGKSSAIYKRGSFKGPRNQFGEFAFITVTTDGKVAVWYQRGKKFFSKIITHLRYPSKRISHVDIILNSDGNYTLATYCPEFLPKLVMFYEIKINMLSLQVSCRPIANVHLTNPSLSVERSPVLHLKLISNTQSHGVRLIIVTAEKKGNNVFNSSIATWEIDKITPQPLDSLTENAMEIDMPLPSIHLVASEHLDQKLVTNIWIQDDELFLGLSDGQVQFRNCNTLQVLSQEQIGLKHFKDCNFPKYSTWVPSNCGHEELSTRADAIIEFATSPNGTLFLCRRASGKLDCLDIADKDVFSNFGLLDGICAASSSANKLTLSILNNIDHTDLENIIKKYANTLEGVGMGKDLLEHTLKETFTNISSVFSDGLETSASSDFLSRLLGIQLSLLKSCQRDNINYLNTLYFLHLRALEAIFQNNVSSDGTFSLDSLKSLVSLTSWIIDFSVYFVQNIYSLVTQGDALLSEKSHIVLLYNSTSRTAFKNLLSLVKKFKDNVNSLAASSPHISNIQEMNGTLQYLFDSWPLKLESLELFIKDTGIITDKVTDKWMKDKNNPQWAKYEIIFTSKVPKALSETLPELKEIFKNRFTSENDIKFYIYDTKWIYSESVDIILKSRTIKDRICARCGYYSAALDVQNTRWAKGYTRSCVCGGLWIDIKEK |
Length | 831 |
Position | Tail |
Organism | Rhizophagus irregularis (strain DAOM 181602 / DAOM 197198 / MUCL 43194) (Arbuscular mycorrhizal fungus) (Glomus intraradices) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Fungi incertae sedis> Mucoromycota> Glomeromycotina>
Glomeromycetes> Glomerales> Glomeraceae> Rhizophagus.
|
Aromaticity | 0.11 |
Grand average of hydropathy | -0.208 |
Instability index | 31.01 |
Isoelectric point | 7.50 |
Molecular weight | 94397.50 |
Publications | PubMed=30271968
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP16765
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 38.81| 10| 27| 175| 184| 1
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175- 184 (18.42/10.82) GKSSAIYKRG
205- 214 (20.40/12.72) GKVAVWYQRG
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 58.37| 20| 22| 776| 797| 2
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776- 797 (27.33/24.14) YSESVDiILKSRTIK..DRICArC
800- 821 (31.04/17.66) YSAALD.VQNTRWAKgyTRSCV.C
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
3| 79.01| 26| 27| 498| 524| 3
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498- 515 (23.20/10.92) ..................ID.HT...DLENIIKKYANTLE
517- 544 (30.04/18.54) VGMGKDLL............eHTlkeTFTNISSVFSDGLE
545- 577 (25.78/ 9.77) TSASSDFLsrllgiqlslLK.SC...QRDNI..NYLNTL.
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 44.20| 14| 89| 36| 55| 4
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8- 21 (25.74/14.41) STTSTL.WS.HTDTDI
40- 55 (18.46/15.20) STQNIIaWSpHPNDNL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 70.90| 21| 22| 695| 716| 5
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695- 716 (30.82/22.48) WpLKLESLELFIKDTGIITDKV
720- 740 (40.08/24.21) W.MKDKNNPQWAKYEIIFTSKV
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 51.33| 19| 27| 445| 465| 6
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445- 465 (27.06/25.77) SPNGTL.FLCrRASG...KLDcLDI
472- 494 (24.27/12.50) SNFGLLdGIC.AASSsanKLT.LSI
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 161.03| 49| 398| 233| 288| 7
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233- 288 (80.09/85.99) SHVDIILNSdgnytlaTYCPEFLPKLVMFYEIKINMLSLQVSCRPIANVHLTNPSL
640- 688 (80.93/67.86) SHIVLLYNS.......TSRTAFKNLLSLVKKFKDNVNSLAASSPHISNIQEMNGTL
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 91.71| 28| 160| 582| 614| 11
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582- 614 (40.61/36.21) LRALEAIFQNNVSSDgtfslDSLKSLVSLTSWI
748- 775 (51.09/32.34) LPELKEIFKNRFTSE.....NDIKFYIYDTKWI
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