<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16714

Description Uncharacterized protein
SequenceMQRYHPTSCTSAVNNSAISGTSARDATRADSSSLPANFSINSRRSTQLTPYKLKCDKESLNSRLGPPDFHPQTPNCPEETLTREYVQNGYKETVEGLEEVREISLTQAQTFNKPVVLKCREAIRKCLRAINESRAQKRKAGQVYGVPLSDSLLTKPGVFPEQRPCGEEFRKKWIEGLSQQHKRLRSLADHVPHGYRKRSLFEVLIRNNVPLLRATWFIKVTYLNQVRHGSANSLSGAQDKIQLSRTEIWTKDVIDYLQHLLDEFFSRNNSHSTQYSRDRSPQTLYTGSPQQRSDPAAVINSEEPSLHFKWWYMVRLVQWHLAEGLLLPSYIIEWVLNQLKDKELLEILQLVLPIIYGVLETVVSSQTYVRSLVGIATHFIREPSPGGSDLVDNSRRAYTISALAEMLRYLILAVPDTFVALDCFPLPSCVVSYAANDGNFVSKASEDVGKMKNYSTDAICVFRGKAVDAQYQSLSFDNVISAIQRRADNLAKDASPGYPGHSVAKAVQALDKALLQGDIREAYKHLFEDLCDAALDESWIAEVSPCLRSSLKWIGTVSLSSVCSVFFICEWATCDFRDFRTVPPHGMKFTGRKDFSQIYVAIRLLKQKIRDLHTPPRRKSESTLGIIDNLAKGSRQRNNYANRNFQGNGYEIKNNANRLDGLRINSSDIFETPGPLHDIIVCWIDQHEIHKREGVKRVQHFIMELVRAGIFYPQAYVRQLMVSGILDMNGLDLNRRRRHHRILKVLPGLFLRVALEEARIAEGSQLSEAIHVYSNERRLVLHELLFDQSIYVNVAAQNQKRHMAGGRDGASPSLADQWKTIQPTTGISSGRSGKSDADIEELKASIAVILQLPSSSATSADSGLDESQGSVKRSLGAVSSKMDLSEGTPGCEDCKRVKRQKLCEDRSSVLQIPSPIHSDDEDLWWVRKGPKPLESYKADPPLKSTKQVSRGRQKTVRRTQSLAQLAAARIEGSQGASTSHVCDNKGSCPHHKTGVEGETLKSMDGVRTACYGDIVSIGKALKKLQYVEKRTVTVWLISIARQHIEEAEKTAAKVGQFNRSFVPVEGRISGRWRLSEDELSAILYFMDVCDDLVSATKFLLWLLPKVLNSPSSTINSGRNILMLSRNAENHACGVGEAFLLSSLRRYENIIIATDLIPEALSATMHRAAQVMASNGRVSGSAAYGYARYLLKKYGNMASVIEWEKNFKATCDKRLLSELESGRSLDGELGLPLGVPAGIEDPDDYLRQKISGGQLSRVGLSMRDVVHRHMEEAFHYFYDKERKLFAAGSPRNPAIDKSDDESQIAQQIIIGLMDCFRQTGGAAQEGDPSLLSSAVSAIVGNVIPTMVKIHDFTAGSNYQNYASTTGSLSFARRILRIYITCLCLLKEALGERQSRVFEIALATEASCALARVFTPGKAARSQFQSSPEAHDPNANMSNDILNSSSKVASGRTSKVTAAISALVVGAVLHGVTSLERMVTVFRLKEGLDVIQFVRSTKSNSNGSARSIGTFKLDNSIEVHVHWFRLLVGNCRTVSDGLVVEFLGEPSIVALSRMQRMLPLSLVFPPAYLIFAFVLWRPFILNNSLAVREDIHQMYQSLTMAINDAIRHLPFRDVCLRDCQGFYNLVTADSTDAEFAAMLELNGLDLQLKSMAFVPLRARLFLNAIIDCKMPSSLFKPEDFNRVSGHTESKSHRAENEAKLLDKLVHVLDSLQPAKFHWQWVELRLLLNEQALIDRLENHEMSLAEAIRSLSPSPEKAAASENENNFIEIILTRLLVRPDAAPLFSELVHLFGRSLEDSMLLQAKWFLGGHDVLFGRKTIRQRLVNIAESKGLSTKAQFWKPWGWVNSGFGPGLNRGDKKKLEATSLEEGEVVEEGIDSKRHGKGSNPLFDAEGTSIGQQHVTERAFIELVLPCIDQSSDDSRNTFANDLIKQLNNIEQQISAVTRGANKLTGSVPSGIEVPSNKGSNRKSIRGGSPGLARRLAATADPAPPSPAALRASMSLRLQFLLRLLPLIYTDGEPSGRNMRYLLASVILRLLGSRVVHEDADLSFYPMQSPQSKREVESLPEASSVPSADFSGESLFDRLLLVLYGLLSSCQPSWLRPKPAFKSSNNTSKDSSGFDREIAESLQNDLDHMQLPDTVRWRIQAAIPILLPSVRCSLTCQPPSVPVAALASLQPSISVSGASPGNLNLPQRNPVPLARSATNTGKSKPIPLQQDSDMEIDPWTLLEDGAGSGPSSSNTAAIGSGDQANLQAASWLKGAIRVRRTDLTYIGAVDDDS
Length2277
PositionKinase
OrganismCitrus unshiu (Satsuma mandarin) (Citrus nobilis var. unshiu)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> rosids> malvids> Sapindales> Rutaceae> Aurantioideae> Citrus.
Aromaticity0.07
Grand average of hydropathy-0.282
Instability index51.43
Isoelectric point8.74
Molecular weight252386.46
Publications
PubMed=29259619

Function

Annotated function 
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats
>MDP16714
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.78|      31|     606|     280|     315|       1
---------------------------------------------------------------------------
  280-  315 (50.27/48.63)	SPQTLYTGSP.........QQR..SDPAAV......INSEEPSLhfkWWymVR
  880-  927 (40.51/23.84)	SKMDLSEGTPgcedckrvkRQKlcEDRSSVlqipspIHSDDEDL...WW..VR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      97.43|      31|     606|    1339|    1373|       2
---------------------------------------------------------------------------
 1339- 1373 (42.41/43.07)	GNViPTMVKIHDfTAGSNYQNYASttGSLSFARRI
 1950- 1980 (55.02/36.26)	GSV.PSGIEVPS.NKGSNRKSIRG..GSPGLARRL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.55|      16|     222|     526|     544|       3
---------------------------------------------------------------------------
  526-  544 (25.26/22.02)	LFedlCDAALDESWIAEVS
  749-  764 (27.29/15.13)	LF...LRVALEEARIAEGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     181.04|      60|     779|    1375|    1481|       4
---------------------------------------------------------------------------
  456-  517 (97.11/47.66)	TDAIC....VFR.GKAVDAQYQSLSFDNVISAiqRRADNLAKDASPGYPGHS..VAKAVQAL.DKALLQG
 1402- 1469 (83.93/134.44)	TEASCalarVFTpGKAARSQFQSSPEAHDPNA..NMSNDILNSSSKVASGRTskVTAAISALvVGAVLHG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     256.92|      84|     779|     319|     411|       5
---------------------------------------------------------------------------
  319-  411 (124.75/114.30)	WHLAEGLLLPSYIIEwvlnqlKDKELLEILQLVLPIIYGVLET.VVSSQTYVRSLVgIATHFIREP.....SPGGSDLVDNSRraYTISALAEMLRYLI
 1101- 1190 (132.17/94.13)	WLLPKVLNSPSSTIN......SGRNILMLSRNAENHACGVGEAfLLSSLRRYENII.IATDLIPEAlsatmHRAAQVMASNGR..VSGSAAYGYARYLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.27|      27|     779|     223|     277|       6
---------------------------------------------------------------------------
  242-  268 (47.27/65.85)	QLSRTEIWTKDVID.YLQHLLDEFFSRN
 1253- 1280 (44.00/10.58)	QLSRVGLSMRDVVHrHMEEAFHYFYDKE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16714 with Med12 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ESYKADPPLKSTKQVSRGRQKTVRRTQSLAQ
2) GASPGNLNLPQRNPVPLARSATNTGKSKPIPLQQDSDMEIDPWTLLEDGAGSGPSSSNTAAIGS
3) MQRYHPTSCTSAVNNSAISGTSARDATRADSSSLPANFSIN
4) RHMAGGRDGASPSLADQWKTIQPTTGISSGRSGK
5) TGSVPSGIEVPSNKGSNRKSIRGGSPGLARRLAATADPAP
934
2181
1
801
1949
964
2244
41
834
1988










Molecular Recognition Features






MoRF SequenceStartStop




1) IGAVDD
2270
2275