<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16630

Description mediator of RNA polymerase II transcription subunit 15a
SequenceMEANSWRLAQGEASADDSASVDWRTQLQHESRQRIVNKIMDTLKRCLPIVPGSLNELQKIAVRFEEKIYTAATSQTDYLRRISLRMLSMETKTQHTPPINPSMLNPAVPNQNPTEPVPLGNEGQSLMTPMVNLPTARQQLLPQNFQNNTSAAVQSSANLPSTLSSITGLSQSNISSVCQTSNLQNMPGISQNSANSSVGQGATPDIYANAQRQMQGRQQQQQINSQQQQQSQNQLNYQHQLQQQLRKQKLQHSSLMQPHLQQQSLLQPTQLQSSQQSVMQMSSGLQSGQSSTRQTQPTTMQSAAPPGLQQNQLNPVQQSVPSLLQQHPQLVSRQQAPPSRHQQTPSLQQQPTPVPQQSNLSLQQQQQQLMGKQTNISNMQQSQLLGQQNSVPDMQQQQQQQHQRLPVQQNSLLGMQQPQQMLNQQSISLHQQQQLGHESNISGVQQQQQQQQQQQLLGSLPNVSNMQVHQRSMHILPQPKTVTQPQQENQQTSLALLQPQGQQSQHQSTQQQIISQFQSQPAQLQQQLAMQQQPNSLERPMQQRLQASGGLLQSQNAIEKQKQFVQAQRVLPEVSSSTSVDSTAQTGHAGVADLQEEIYQKIKSMREMYFADLNELYQKIALKLQQHDAHIPPAKQSEQYEKMKSFKIMLERTLMILQISKNNIQPGLKEKLPLYEKQIVSFLASNKKKIVPSQPQGQQQFQHPGGLAYSSQVSQLQQHDNHPNQVQHMNLQGSATSMQPAAVTGMQHVSMPLPTHSGVPTTQQNIANALQPGSNSDSAQGSSFNSLQQGATGSMPQGGGGSGPSTINAPQQTNAKALSNSSMNTLQPNASLMQPSSNTLQQQHLKQQQQEQQQQLMQTQQMKQQFQQRHMQQQLLQQQQKQQLMQSQSSLQQQLHKQQKQQPAPMLAHQISQLHQTNEANESKVRPGLGIKPGLYQQHYSAGQRHGYYHQQLKPSASGASFPISSPQNLQVLSPQISHHSSPQADQHSLLPSQVKAGTPLQSASSPFVPSPSTPLAPSPLPADSEKQLSGISSLANAGHVGHQQSALAPPQALAVGTPGISSSSIPAESTSPDGNQANVPSIAPDKKSASEWPLERLIKVVKSSSPKALSSAISDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKCRLQARNFMSQDGNAAAKKIKHNTSAMPLNNMSSAGSVNDSVKQTYGLDTSELESTATSRVKRQKIEVNHALLEEIREINQQLIVTIVNISEEDADSVAAASDGEGTVIKCSFTAVALSPTFKSQFASSHMSPILPLRLLVPANYPKCSPVLLDNLPDESSGESDDLSVKAKSRFSISLRGLSQPMSLGEMARRWDACARKVIAEYAQQTGGGSFSSRYGAWENCVA
Length1376
PositionTail
OrganismPhoenix dactylifera (Date palm)
KingdomViridiplantae
Lineage
Aromaticity0.03
Grand average of hydropathy-0.731
Instability index75.27
Isoelectric point9.38
Molecular weight150797.02
Publications









Function






Annotated function


ECO:0000256	ARBA:ARBA00003669
ECO:0000256	RuleBase:RU364150

GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats
>MDP16630
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     322.00|      38|      38|     306|     343|       1
---------------------------------------------------------------------------
  258-  302 (38.06/ 6.99)	PH.L..QQQsllqptQLQSS.QQSV...MQM.SSGLQSGQsstrQ.TQPTTMQS
  306-  343 (75.72/23.28)	PG.L..QQN......QLNPV.QQSVPSLLQQ.HPQLVSRQ....Q.APPSRHQQ
  345-  381 (53.41/13.63)	PS.L..QQ.......QPTPVpQQSNLSLQQQ.QQQLMGK.....Q.TNISNMQQ
  442-  471 (38.44/ 7.15)	SG.V..QQQ......QQQQQ.QQQ...LLGS.LPN.VSNM....Q.V....HQR
  479-  508 (39.47/ 7.60)	PK.TvtQPQ......QEN...QQTSLALLQ...PQ..GQQ.........SQHQS
  760-  798 (36.57/ 6.35)	PT.T..QQN......IANAL.QPGSNSDSAQ.GSSFNSLQ....QgATGSMPQG
  873-  910 (40.33/ 7.97)	QQlL..QQQ......QKQQL.MQSQSSLQQQlHKQ..QKQ....Q.PAPMLAHQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      57.53|      11|      16|     592|     602|       2
---------------------------------------------------------------------------
  592-  602 (20.88/12.13)	ADLQEEIYQKI
  611-  620 (18.85/10.20)	ADL.NELYQKI
  634-  643 (17.80/ 9.20)	AK.QSEQYEKM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      77.49|      18|      19|     984|    1001|       4
---------------------------------------------------------------------------
  984- 1001 (31.07/12.37)	QADQHSLLPSQVK..A.GTPL
 1002- 1021 (21.74/ 6.29)	QSASSPFVPSPSTplA.PSPL
 1042- 1060 (24.68/ 8.21)	GHQQSALAPPQAL..AvGTPG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.37|      14|      16|      86|     101|       8
---------------------------------------------------------------------------
   86-   99 (25.06/ 8.35)	MLSMETKTQH.TPPI
  103-  117 (20.30/ 9.11)	MLNPAVPNQNpTEPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.02|      34|     189|     218|     254|       9
---------------------------------------------------------------------------
  218-  251 (63.89/16.23)	QQQQQINSQQQQQSQN................QLNYQHQLQQQLRKQKLQ
  823-  872 (41.12/ 6.95)	MNTLQPNASLMQPSSNtlqqqhlkqqqqeqqqQLMQTQQMKQQFQQRHMQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.92|      24|     107|     408|     435|      11
---------------------------------------------------------------------------
  408-  434 (37.06/22.32)	QQ..NSLlgMQQPQQMLnQQSISLHQQQQ
  531-  556 (37.86/10.53)	QQqpNSL..ERPMQQRL.QASGGLLQSQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      79.53|      26|      43|     135|     160|      12
---------------------------------------------------------------------------
  132-  157 (45.62/22.12)	NLP...................TARQQLLPQNFQNNTSAAVQSSA
  158-  202 (33.91/14.26)	NLPstlssitglsqsnissvcqTSNLQNMPGISQNSANSSVGQGA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      63.36|      19|      65|    1100|    1120|      13
---------------------------------------------------------------------------
 1061- 1077 (22.96/11.89)	..ISSSSIPAEST..SPDGNQ
 1078- 1092 (16.57/ 6.09)	ANVPSIAPDKKSA..SE....
 1100- 1120 (23.83/20.15)	KVVKSSSPKALSSaiSDIGSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.90|      13|      19|     951|     963|      14
---------------------------------------------------------------------------
  951-  963 (23.95/10.30)	QQLKPSASGASFP
  971-  983 (24.94/11.05)	QVLSPQISHHSSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.10|      14|     226|     706|     719|      15
---------------------------------------------------------------------------
  706-  719 (25.81/14.97)	GLA...YSSQVSQLQQH
  930-  946 (17.29/ 6.54)	GIKpglYQQHYSAGQRH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      80.40|      21|     606|      38|      68|      16
---------------------------------------------------------------------------
   38-   58 (38.71/16.65)	KIMDTLKRCLPIVPGSLNELQ
  647-  665 (31.88/11.38)	KIM..LERTLMILQISKNNIQ
  682-  692 ( 9.81/ 8.75)	FLASNKKK...IVP.......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.36|      24|     107|    1130|    1154|      17
---------------------------------------------------------------------------
 1121- 1144 (39.21/25.77)	VSMID.RIAG....SAPGNGSRAAVGEDL
 1145- 1173 (29.15/23.61)	VAMTKcRLQArnfmSQDGNAAAKKIKHNT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.05|      16|     615|     571|     586|      18
---------------------------------------------------------------------------
  571-  586 (27.92/17.74)	LPEVSSSTSV.DSTAQT
 1178- 1194 (24.13/14.20)	LNNMSSAGSVnDSVKQT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     154.94|      47|      48|    1267|    1313|      19
---------------------------------------------------------------------------
 1267- 1313 (81.39/52.83)	LSPTFKSQFASSHMSPILPLRL.LVPANYPKCSPVLLDNLPDESSGES
 1316- 1363 (73.54/46.93)	LSVKAKSRFSISLRGLSQPMSLgEMARRWDACARKVIAEYAQQTGGGS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16630 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) METKTQHTPPINPSMLNPAVPNQNPTEPVPLGNEGQSLMTPMVNLPTARQQLLPQNFQNNTSAAVQSSANLPSTLSSI
2) QQQQQQLLGSLPNVSNMQVHQRSMHILPQPKTVTQPQQENQQTSLALLQPQGQQSQHQSTQQQIISQ
3) SVCQTSNLQNMPGISQNSANSSVGQGATPDIYANAQRQMQGRQQQQQINSQQQQQSQNQLNYQHQLQQQLRKQKLQHSSLMQPHLQQQSLLQPTQLQSSQQSVMQMSSGLQSGQSSTRQTQPTTMQSAAPPGLQQNQLNPVQQSVPSLLQQHPQLVSRQQAPPSRHQQTPSLQQQPTPVPQQSNLSLQQQQQQLMGKQTNISNMQQSQLLGQQNSVPDMQQQQQQQHQRLPVQQNSLLGMQQPQQMLNQQSISLHQQQQLGHESNISGVQQQQ
4) VPSQPQGQQQFQHPGGLAYSSQVSQLQQHDNHPNQVQHMNLQGSATSMQPAAVTGMQHVSMPLPTHSGVPTTQQNIANALQPGSNSDSAQGSSFNSLQQGATGSMPQGGGGSGPSTINAPQQTNAKALSNSSMNTLQPNASLMQPSSNTLQQQHLKQQQQEQQQQLMQTQQMKQQFQQRHMQQQLLQQQQKQQLMQSQSSLQQQLHKQQKQQPAPMLAHQISQLHQTNEANESKVRPGLGIKPGLYQQHYSAGQRHGYYHQQLKPSASGASFPISSPQNLQVLSPQISHHSSPQADQHSLLPSQVKAGTPLQSASSPFVPSPSTPLAPSPLPADSEKQLSGISSLANAGHVGHQQSALAPPQALAVGTPGISSSSIPAESTSPDGNQANVPSIAPDKKS
89
450
176
691
166
516
448
1089










Molecular Recognition Features






MoRF SequenceStartStop




1) WPLERLIKV
1093
1101