<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16505

Description Mediator of RNA polymerase II transcription subunit 13
SequenceMEPGECLSNVISFNNFASINYEYFESQTAPAGSARDHLQRTEAGWRQEGRLVQYDPYRDGIWLFQNVTGTGSPTKHSEISAVDVQGLGLLLKDKGTYDPASLARGKQASNVLTTPSTSSSPSSSLESALRNAQALNARSVQANFNLGLVQDSPTPSPGLKPELHNSLKDIHENFISSVLSSTVYFLCYEHGFIPLNSRTLILPFSNSSPLSFRPRNSIELATLDISLTSLGVLVIKAHADMAPGLQTSVSATSSASIASELSPGSSLWLAPSGSAAKLHSIPDEKKLPESMSMAQLQEDPLESRSSGTNSLTIKAWQSRCLEWLSAKGLNSTALEAGGWIHVQILGGHNPYYNGDTQAIPILDESAIVPWPALLCFQTSNSRFQDAQLNGSGSWPCRDPLSFAEDWFTSGDERAATVSNRQKERQAVEALSKEQADLETRALQSNTYSPTALRRSSNAGAMYPTPPDAPQPHVGATPSFDGNAXTCGDQRRSSGNTYNDNEKDNDHDNDNGNENLFGDIGGDMFGTHITDDDFNFFDEPDVDELDQKAPSPLPGNLPEIQEEAIMSKKPFPSEIMIQVLETHDAELPSTDHGAPSRQTDNSKNSQPTGITAQISSSEQSNDNVEAVKSPRPYVSLPFSKEVIFQRLDQERIGRKNSKQFRRASLFSRIVFEESLQSVNKKYSSHGQFSFSSKKTRKHEIVPGLPETDYLSSRRKPRDRILEMRNVARIIGEKKLDCEPNIRDPMDHLLASDESSPMSEQDDSSHATEESLVSPLNGMKRKWESDEQDDIASTFDGLAMDFEVSASTPQSASGSQMPLLDADPADWALATYFTTPEPDVDAELNVLTDLERIATAQILADQAIWGTLRLPDTASNETSMLADATSATRQLMHSLTQALKSCLKDGNTCTMRSFMDIQGIPVLNQALRLPPRPMQNLRGPIGQDARPNTLFPIPPPQLEVRRSDMKMSILPASVPFWENLGLGPSKGTKDVNAVCVYPNFDGLAMCASAFLDQMKSVYESSRFGTHDRLVSKEIGNGLLPFAIDLLSQDKMQYLAVLRETVSRLSRNLASSTAGEKNYVIYFVYPVDNKVLLVHICSAFQHLFNLYRKAVSERRPSSVNELVLQLVPMDLIASPTSVAVPLPSKYFKLSMEVYDRCINFSSSTSSPAIMLEQPLPRTIDFKLSVNPSASVLQENTCLHIAYAQSIDDRWITAAWTDNMGTQQMTASYCLGRKNEPISTPFTDVANEIWETTLQILLSQKIHWRIIIARVGVMDNSELDFWIGLASTESNAQISLTLVTVQTNPSLRLLPAPVTLTPNGSTAQSVITPVSTPQALQTSIGSPDTATTPIRGVPTSVSTPVEAPIEPDSDARLVDYADRSWGAVLSHRLNNSNSLVESNPALISGYLLKRGGLNNNDPPIVMEVNIVHSEVVGNPRTFHESILREVLGYYRGLGTLARTRGVVDAVKDIRPWHIAAAEKAVKALYMLM
Length1484
PositionKinase
OrganismDiplocarpon rosae
KingdomFungi
Lineage
Aromaticity0.07
Grand average of hydropathy-0.365
Instability index50.41
Isoelectric point5.17
Molecular weight162645.64
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16505
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.44|      29|      34|     103|     131|       1
---------------------------------------------------------------------------
  103-  131 (48.14/26.59)	ARGKQASNVLTTPSTSSSPSSSLESALRN
  137-  165 (52.30/29.63)	ARSVQANFNLGLVQDSPTPSPGLKPELHN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.15|      17|      34|    1313|    1329|       2
---------------------------------------------------------------------------
 1313- 1329 (31.39/17.13)	TPNGSTAQSVITPVSTP
 1344- 1360 (31.77/17.43)	TPIRGVPTSVSTPVEAP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.10|      31|      34|     836|     867|       3
---------------------------------------------------------------------------
  836-  867 (48.75/39.46)	PD.VDAELNVLTDLERiATAQILAD..QAIWGTLR
  869-  902 (42.35/28.58)	PDtASNETSMLADATS.ATRQLMHSltQALKSCLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      36.27|      10|      34|    1138|    1147|       4
---------------------------------------------------------------------------
 1138- 1147 (20.54/10.21)	PLPSKY.FKLS
 1171- 1181 (15.73/ 6.24)	PLPRTIdFKLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.62|       8|      34|     453|     462|       5
---------------------------------------------------------------------------
  453-  462 (11.95/11.47)	RRSSnaGAMY
  490-  497 (16.67/ 8.22)	RRSS..GNTY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.68|      20|      34|     557|     578|       6
---------------------------------------------------------------------------
  557-  578 (30.45/25.15)	PEIQEEAimSKKPFPSEIMIQV
  594-  613 (35.23/21.85)	PSRQTDN..SKNSQPTGITAQI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.24|      21|      25|     637|     659|       7
---------------------------------------------------------------------------
  637-  659 (28.13/26.95)	FSKeVIFQRlDQERIGRKNSK..QF
  665-  687 (31.11/19.32)	FSR.IVFEE.SLQSVNKKYSShgQF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.22|      33|      34|     999|    1032|      10
---------------------------------------------------------------------------
  999- 1032 (53.39/41.39)	DGLAMCASAFLDQMKSVYESSRFGTHDRLvSKEI
 1034- 1066 (54.83/37.69)	NGLLPFAIDLLSQDKMQYLAVLRETVSRL.SRNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.28|      13|      27|     919|     933|      12
---------------------------------------------------------------------------
  919-  933 (20.63/15.72)	PvlNQALRLPPRPMQ
  945-  957 (25.65/13.33)	P..NTLFPIPPPQLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.64|      23|      27|    1253|    1275|      13
---------------------------------------------------------------------------
 1253- 1275 (38.86/34.63)	LLSQKIHWRIIIARVGVMDNSEL
 1281- 1303 (35.78/31.12)	LASTESNAQISLTLVTVQTNPSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      47.96|      14|      35|     289|     302|      14
---------------------------------------------------------------------------
  289-  302 (24.36/12.55)	ESMSMAQLQEDPLE
  322-  335 (23.61/11.95)	EWLSAKGLNSTALE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      28.36|       9|     572|     512|     544|      17
---------------------------------------------------------------------------
  503-  511 (18.21/38.73)	DNDH......DNDNG
  530-  544 (10.15/ 7.55)	DDDFnffdepDVDEL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.85|      24|      34|     353|     382|      18
---------------------------------------------------------------------------
  353-  382 (33.38/29.94)	NGdTQAIPILDE.SAIVPWpallcFQTSNSR
  389-  413 (44.47/22.23)	NG.SGSWPCRDPlSFAEDW.....FTSGDER
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16505 with Med13 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DERAATVSNRQKERQAVEALSKEQADLETRALQSNTYSPTALRRSSNAGAMYPTPPDAPQPHVGATPSFDGNAXTCGDQRRSSGNTYNDNEKDNDHDNDNGNENLFGDIGGDMF
2) NIRDPMDHLLASDESSPMSEQDDSSHATEESLVSPLNGMKRKWESDEQ
3) THITDDDFNFFDEPDVDELDQKAPSPLPGNLPEIQEEAIMSKKPFPSEIMIQVLETHDAELPSTDHGAPSRQTDNSKNSQPTGITAQISSSEQSNDNVEAVKSP
4) TPQALQTSIGSPDTATTPIRGVPTSVSTPVEAPI
411
739
526
1328
524
786
629
1361










Molecular Recognition Features






MoRF SequenceStartStop




NANANA