<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16495
Description |
Mediator of RNA polymerase II transcription subunit 20 |
Sequence | MGFSGLARWLNAPTTALPLIRENILVNHNGRLEGKWQLSVKSFRSTLSQSDGSQVPSERSMCALTMGENVFVLLDDPGAPSRIEAENLTQPPTHYRNTFLTLSPPGALEHLLAQLKARWVSVRQSTANTAPRTQAAGPQLLIDGHVFSIGTDWIVRIGNVVLSGGAVKGMLLEAEYLPLPVLSSPLQDGTSELLSNLLTSILPNIRDAKTVAITISDSQWEDVLWNREEEEKEKRSKEERMPVDEDDIYVYGDEEEDGKQQPRDWTGVDRDRRSAFLIMAALRSEGIL |
Length | 288 |
Position | Head |
Organism | Armillaria gallica (Bulbous honey fungus) (Armillaria bulbosa) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes>
Agaricomycetidae> Agaricales> Physalacriaceae> Armillaria.
|
Aromaticity | 0.06 |
Grand average of hydropathy | -0.342 |
Instability index | 64.95 |
Isoelectric point | 4.96 |
Molecular weight | 31957.73 |
Publications | PubMed=29085064
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364152
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP16495
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 85.76| 24| 26| 221| 246| 1
---------------------------------------------------------------------------
222- 245 (41.46/27.12) DVLWNREEEEKEKRSKEERMPVDE
247- 270 (44.31/29.99) DIYVYGDEEEDGKQQPRDWTGVDR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 93.84| 26| 26| 53| 78| 2
---------------------------------------------------------------------------
53- 78 (46.45/31.20) SQVPSERSMCALTMGENVFVLLDDPG
81- 106 (47.40/31.97) SRIEAENLTQPPTHYRNTFLTLSPPG
---------------------------------------------------------------------------
|