<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16477

Description Uncharacterized protein
SequenceMKGHEQSSIPLYKSQPPAWLPKAHSAGELGYPGFYPPHSGQEEDILSESNIKNGFVLPPSVQMETYSAQSTVTESLHGQDTISKLEELMNEVFARRLHQIPSIPLSTFRVPSRVTLNDTKRQAWFADLANPDVPLNKLGKSVPHGAKGHDLLDLLHSNNIAIPRAVWFLRVFGANETAGLRNRPSYNPTQYSVEWAGVVTGYMKKQLADIALPSAPRPGMNIKQTFKGVLADTGTRDRWISRFTYCLKLLRAFYKEGLVDRRTFLVWVVHQMGICNLAQAGFIARIADEYLEGMMSSRPLTRPFVEACVSKLSEIGSSASREFLVDTEGLLKAILQRFCLALPDAFVSPRMWAIHSSLLLAVLTENIMDQTFDGQNPSEIHQVLVRNVADIQRRNEAMLFYNLPPLASDRLGSSVLDIKLLNSISRTTDINSISFFSDNVLDDPKHKLDMLLTWSITPLQFGDHRPFAAITLIRNWRQRAGERALRREDRSPDEFIQDQLFNWLDSSEVAGDPKNIRAVALLFGKLIQRELFSYGSYIQRLIARGEQGMSFNDAVESRHRLFLRWISLSEPSQLNQRKVTLYGVRARDTPEEGTERQMRKEIRAAMPQLFEGGPEPLLKSPEALFRRCKTFVSSPLYEQVRTLKLWLLPILEKSISSISVIDNVLKSYCIAVELMAETKCFRSILSLTLCLLEHASTTDSLNTAIDTLRRFHTLWSCMDVVGSIVTSLQTAHQIWKSKGMQTRVLLVLLKELDDNRFLSAQARDQLNAEISYYSMTLQPVIVGHPEPVPSVLPEILLLAGDYEEEAPSTLANGLWIKYRMSFDWAWKVWDNTIASLRQIPLMVPDTEGRRGCALRYATFLRHVDHLLPTGLDDHVLGWFLGPGKSEVVNLTADVWDIVTLLLLGLVVNGALKTTTIMTGLVYPAWQCASSSVELPLQQMEVFLAAANNLVQGLLLRGEGSSGIMPPCDLFDVQRLQTRKQDVYCEPHFPALVSNIPILVSLENNERIPEHLRTELKVIRHSLYEDDNFRQGTFRNLDALREAFEQAMQLKENTSPEVGDRTMAALRMIFSEAPDEDIEISSWPEKSSFLSPWMISATTIQLQFFLKQMERSINKESHAYDTACMTLDKLTSVIFDHTLSSDEACFVTQMTQGVGSAVAGKIINNGLRFLTGVLRDPSSDTGTSLARAGESFRILIYVAEPLRQESAHLPVLDPDVQDMFFSTLCSKFASIEEATHNPDAMTVDRTDFTQEVVLLARFLQFDLSFEGAWTASTTESSRKLCASLYRLTLLFASGNTFDPIAYPLLLDTLYYLIDEAPTSTKMNAFDPFINYPDITPSDFAPDIPFHYLTQLRSLLPHLPAVSSVADLASCHRDPTGKLVQDAPVVNRPWEWIENLGEPSVPEERFREGEDRVKYQVKNSGSISLDTFGARMTGEGIIASKHDDERIEANMRMFEDGLSADNVFKRDWRETRLTVEIEGMALTAGRKAGMSGSQELGPRVASPGASSSRIGKSPARSSLHRSTNSTRSGSVEIIDVDSVSSSTMRKGVKRKAATSDDEVIIVDGPSQGGSSSSKKSKPKRKR
Length1580
PositionKinase
OrganismArmillaria gallica (Bulbous honey fungus) (Armillaria bulbosa)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Physalacriaceae> Armillaria.
Aromaticity0.08
Grand average of hydropathy-0.211
Instability index47.81
Isoelectric point5.99
Molecular weight177062.13
Publications
PubMed=29085064

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16477
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|    1603.89|     538|     880|      17|     657|       1
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   17-  657 (799.57/744.60)	PAWlPKAHSAGELgypgfypphsgqeedilsesnikngfvlpPSVQMETY.SAQSTVTESL....HGQDTISKLEELMN.EVFARRLHQI...PSIPLSTFRVPSRVTLNDTKRqawfadlaNPDVPLNKLgKSVPHGAKGHDLLDLLHSNNI.....AIPRAVWFLR....VFGANETAGLRNRPSYNPTQySVEwagVVTGYMKKQLADIALPSAPRPGMN..IKQTFKGVLADTGTRDrwisrfTYCL...KLLRAFYKEGL.VDRRTFLVWVVHQMGicnLAQAGFIARIADEYLEGMmssrpLTRPFVEACVSkLSEIGSSaSREFLVDTEGLLK..AILQRFCLALPDAFVS.....................PRMWAIHSSLLLAVLTEniMDQTFDGQNPSEIHQVLVRNVADIQRrnEAMLFYN...LPPLASDRLGSSVldIKLLNSISRTTDINSisffsdnvlddpkhkLDMLLTWS.ITPLQFGDHRPFAAITLIRNWRQR....AGERALRREDRSP.DEFIQD.....QLFNWLdssEVAGDP....KNIRAvallfGK.LIQRELFSYGSY.IQRLIARgeqgMSFNDAVESRH.........RLFLRWISLSEPSQLNQRKVTLygvrardTPE.EGTERQMRKeiRAAMPQLFEGGPEplLKSPEALFRRC.KTFVSSPLYEQVRTLKLWLLPILE.KSISS
  923- 1539 (804.31/527.88)	PAW.QCASSSVEL.............................PLQQMEVFlAAANNLVQGLllrgEGSSGIMPPCDLFDvQRLQTRKQDVycePHFPALVSNIPILVSLENNER........IPEHLRTEL.KVIRHSLYEDDNFRQGTFRNLdalreAFEQAMQLKEntspEVGDRTMAALRMIFSEAPDE.DIE...ISSWPEKSSFLSPWMISATTIQLQffLKQMERSINKESHAYD......TACMtldKLTSVIFDHTLsSDEACFVTQMTQGVG...SAVAGKIINNGLRFLTGV.....LRDPSSDTGTS.LARAGES.FRILIYVAEPLRQesAHLPVLDPDVQDMFFStlcskfasieeathnpdamtvDRTDFTQEVVLLARFLQ..FDLSFEGAWTASTTESSRKLCASLYR..LTLLFASgntFDPIAYPLLLDTL..YYLIDEAPTSTKMNA...............FDPFINYPdITPSDFAPDIPFHYLTQLRSLLPHlpavSSVADLASCHRDPtGKLVQDapvvnRPWEWI...ENLGEPsvpeERFRE.....GEdRVKYQVKNSGSIsLDTFGAR....MTGEGIIASKHdderieanmRMFEDGLSADNVFKRDWRETRL.......TVEiEGMALTAGR..KAGMSGSQELGPR..VASPGASSSRIgKSPARSSLHRSTNSTRSGSVEIIDvDSVSS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16477 with Med12 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) GMALTAGRKAGMSGSQELGPRVASPGASSSRIGKSPARSSLHRSTNSTRSGSVEIIDVDSVSSSTMRKGVKRKAATSDDEVIIVDGPSQGGSSSSKKSKPKRKR
1477
1580










Molecular Recognition Features






MoRF SequenceStartStop




1) TMRKGVKRKAATSDDEVIIVDGPSQGGSSSSKKSKPKRKR
1541
1580