<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16476

Description Kinase-like protein
SequenceMLDEFSSALHDPMRLYRTKRDDAHRPVASKYSILGFISSGTYGRVYKAQSIGDDQKIHAIKKFKPDKEGDVVTYTGISQSAIREIALNREIDHDNVVSLKEVILEDKSIYMVFDYAEHDFLKVIHHHSQTLRCSISTPVLKSLIYQLFNGLLYLHSCHILHRDLKPANILITSEGVVKIGDLGLARLVYEPLQPLFAGDKVVVTIWYRAPELLMGAKHYNKAIDCWAVGCVMAELASLRPIFKGEEAKLDSKKNVPFQRDQLLKIFEVLGTPDEKDWRGLRNMPEFQNMKRLDYFPNHLHEWCQPRIRSTQGYDLLRHLFAYDPDKRLTASEALQHKWFHEEPLPTWNAFESVAPHQIPPPRRITQDEGPSSMIPMAMNNSHPHQPLMAPGAPFAQPQTQSKPGSSASFASLSGGGGVYVGQGASGNASNPHGRKKARLV
Length440
PositionKinase
OrganismArmillaria gallica (Bulbous honey fungus) (Armillaria bulbosa)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Physalacriaceae> Armillaria.
Aromaticity0.09
Grand average of hydropathy-0.395
Instability index40.73
Isoelectric point8.73
Molecular weight49678.33
Publications
PubMed=29085064

Function

Annotated function 
GO - Cellular Component
euchromatin	GO:0000791	IEA:EnsemblFungi
mediator complex	GO:0016592	IEA:EnsemblFungi

GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
cyclin-dependent protein serine/threonine kinase activity	GO:0004693	IEA:EnsemblFungi

GO - Biological Process
positive regulation of transcription by RNA polymerase II	GO:0045944	IEA:EnsemblFungi









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16476
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.42|      25|      27|     345|     371|       1
---------------------------------------------------------------------------
  345-  371 (42.03/34.93)	PTwnAFESVAPHQ..IPPPRRITQDEGPS
  375-  401 (42.39/26.72)	PM..AMNNSHPHQplMAPGAPFAQPQTQS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      77.70|      23|     289|       2|      25|       3
---------------------------------------------------------------------------
    2-   25 (38.27/33.00)	LDEFSSALHD...PmRLYRTKRDDAHR
  292-  317 (39.43/28.02)	LDYFPNHLHEwcqP.RIRSTQGYDLLR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16476 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AFESVAPHQIPPPRRITQDEGPSSMIPMAMNNSHPHQPLMAPGAPFAQPQTQSKPGSSASFASLSGGGGVYVGQGASGNASNPHGRKKARLV
349
440










Molecular Recognition Features






MoRF SequenceStartStop




1) HGRKKARLV
432
440