<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16466
Description |
Mediator of RNA polymerase II transcription subunit 6 |
Sequence | MDINDLHPPDDYSHRFFIWHEWIQANGPLTSENVFEYFATSMFYDKQSNNQVLRMQTMHTDVAVMNEAEELKRFTGVEFAVVHAQPPSFFIIQKRERLSPEEVIPLSAYFIINNRIYQSPDLYTVLSNRLLTSLTSLQTSLDILRSHRPDYTPRTGFVWPITDPSLDETAKKPAADDLTGANTPMPDDNTNPADGNGKRQQNTMLLFNAMRATALHSSSAVSSSAFAQMTSSTVPPTEIQAHAQAQVQTPAAVTQASTVPSQASTPAPPPQEPPGRGPPGGGKKKRKRTLLPVPGS |
Length | 296 |
Position | Head |
Organism | Armillaria solidipes |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes>
Agaricomycetidae> Agaricales> Physalacriaceae> Armillaria.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.511 |
Instability index | 48.48 |
Isoelectric point | 6.06 |
Molecular weight | 32731.35 |
Publications | PubMed=29085064
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364143
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro
|
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro
|
Interaction
Repeat regions
Repeats |
>MDP16466
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 64.32| 18| 18| 90| 107| 1
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90- 107 (31.57/21.62) FIIQKRERLSPEEVIPLS
110- 127 (32.75/22.68) FIINNRIYQSPDLYTVLS
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 68.24| 18| 137| 1| 19| 2
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1- 19 (35.28/22.63) MDINDLHPPdDYSHRF.FIW
141- 159 (32.95/16.64) LDILRSHRP.DYTPRTgFVW
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 53.20| 16| 23| 232| 250| 3
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232- 250 (25.93/20.42) STVPPteiQAHAQA.QVQTP
257- 273 (27.28/13.73) STVPS...QASTPApPPQEP
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 24.06| 7| 23| 160| 169| 5
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160- 169 ( 8.55/10.17) PITDpslDET
184- 190 (15.51/ 6.73) PMPD...DNT
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