<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16418

Description Uncharacterized protein
SequenceMTLMIDENFKKELTMKRERVEDLFYFENSKEIGRGTYGLVYKAVPKHPNGRFPNKEYALKMIEGQGFSMSACREIALFRELRHPNLICLQRVFLTNEKKVWLLLDYAEHDLWHVIKHHRTAKNKKVPIMVPRNMVKNILYQILSGMHYLHSNWVLHRDLKPANILLMGDGPPDMRGRVKIADLGFSRIYANPLKPMAELDPVVVTFWYRAPELLLGAKHYTKAIDVWAIGCIFAELLTAEPLFFCKEEDIKAQNPYHYDQVKRIFHLLGYPNETDWPDMKKMPDHARLLSDARNDGTPITTFPNSLHRYFDKWKIHPQSSPYRLLVKLLTVDPVKRVSCEDAMNDYYFRKMERPPKETDDVFNKYPIPYAKKEQQMTIPVQQPQQMQQPQMNAQQMMGGPPQMAPTQMGQPPMGVPDAGHPGHPMMQQQHPQHPHMQYQQMHDPMQRGMDEGPQAKMMRMANVPVGRGHSQITS
Length474
PositionKinase
OrganismCaenorhabditis japonica
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Chromadorea> Rhabditida> Rhabditina> Rhabditomorpha> Rhabditoidea> Rhabditidae> Peloderinae> Caenorhabditis.
Aromaticity0.09
Grand average of hydropathy-0.606
Instability index48.31
Isoelectric point9.16
Molecular weight55263.67
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16418
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     131.61|      30|      31|     401|     431|       1
---------------------------------------------------------------------------
  383-  398 (26.50/ 8.08)	....PQQMQQPQMNA...........QQMMG
  401-  431 (60.23/30.88)	PQMAPTQMGQPPMGVPDAGhPGHPMMQQQHP
  434-  458 (44.88/18.31)	PHMQYQQMHDPMQRGMDEG.PQAKMM.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.64|      17|      35|     270|     289|       2
---------------------------------------------------------------------------
  270-  286 (36.02/16.20)	YPNETD.WPDMKKM.PDHA
  302-  320 (23.61/ 8.33)	FPNSLHrYFDKWKIhPQSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.96|      17|      37|     118|     134|       5
---------------------------------------------------------------------------
  118-  134 (31.39/17.17)	HRTAKNKKVPIM..VPRNM
  156-  174 (27.57/14.26)	HRDLKPANILLMgdGPPDM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.07|      13|     108|     246|     258|       9
---------------------------------------------------------------------------
  246-  258 (25.73/17.49)	KE.EDIKAQNPYHY
  356-  369 (19.34/11.24)	KEtDDVFNKYPIPY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16418 with CDK8 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) KEQQMTIPVQQPQQMQQPQMNAQQMMGGPPQMAPTQMGQPPMGVPDAGHPGHPMMQQQHPQHPHMQYQQMHDPMQRGMDEGPQAKMMRMANVPVGRGHSQITS
372
474










Molecular Recognition Features






MoRF SequenceStartStop




NANANA