<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16404

Description Uncharacterized protein
SequenceMYPHGVSRLNNRPGSAQAGNYSQPYSHTYNSQNTANQGTSQPAAPSMQLPQPTMMASSSILTLGPYKHRKDLSRHSVLSNYTVIGYIAAGTYGKVYKAKSKGGTATNGSTEDVNEMARQVASENRQTEDDDQKLFAIKKFKSDNHSSMAHALGANHEGGAYTGISQSAIREMSLCRELNHKNITKLMEIMLEGKSIYMVFEFFEHDLLQIIHYHSHPDVKPIPEQTVKSLIWQVLNGVTFLHKNWVFHRDLKPANIMVSSDGVVKIGDLGLARKFNNPLQSLYTGDKVVVTIWYRAPELLLGTRHYTPAIDLWAVGCILAELLSLRPIFKGEEAKFDMNNKKSIPFQKNQLQKIFEILGTPTVEQWPSLPKYPDYYAFQQHFGSKGTLYQPNLGNWYKMIGGKSKGCLALLRDLLHYDPVTRISADDALLHPYFLEAPAVKENAFEGLNVKYPKRRIFTDDIDITAQHPNFSNKRHYDDGSSRKRQRN
Length488
PositionKinase
OrganismCandida auris (Yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora> Clavispora/Candida clade.
Aromaticity0.10
Grand average of hydropathy-0.522
Instability index42.14
Isoelectric point9.25
Molecular weight55124.03
Publications
PubMed=27988485

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein kinase activity	GO:0004672	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16404
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.25|      11|      32|     416|     427|       2
---------------------------------------------------------------------------
  416-  427 (17.29/20.04)	HYdPVTRISADD
  451-  461 (21.96/17.97)	KY.PKRRIFTDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.75|      27|      59|      98|     124|       3
---------------------------------------------------------------------------
   98-  124 (45.01/33.36)	AKSKGGTATNGSTEDVNEMA..RQVASEN
  154-  182 (42.73/31.30)	ANHEGGAYTGISQSAIREMSlcRELNHKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.17|      16|      27|     351|     366|       5
---------------------------------------------------------------------------
  351-  366 (29.68/15.23)	LQKIFEILGT...PTVEQW
  378-  396 (27.50/13.70)	FQQHFGSKGTlyqPNLGNW
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16404 with CDK8 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AKSKGGTATNGSTEDVNEMARQVASENRQTE
2) MYPHGVSRLNNRPGSAQAGNYSQPYSHTYNSQNTANQGTSQPAAPSMQLPQPTMMASSSILTLGPYKHR
98
1
128
69










Molecular Recognition Features






MoRF SequenceStartStop




NANANA