<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16402

Description Uncharacterized protein
SequenceMNNIPAPMGGTWHSKQNPDERQKIIQIVVATLKDIQGVDFNEATAIKQAHDFEKYMFMKCTSRDEYLNQIKQKVHQMRGSLRNNSGTGMQQPQNPQNAQNVQNQQFSAHARQAQAHQQQQQQQQQQQQHQQQQIPGQQNIGLGLGTDAANQGMNFFPQNQMQMRNGMMPQSSPQQGHQQVPQAQMNRAAPQQQMPQQQQQQQQHQQQQNSSSGPQQGSGPQGINRNIGNQLTPQQIQQLSAMIKNVPIPPVFLNKIPNLPPNVNTWARIYDLAQKKVIPSSSLPAIKEVHNAHLSIVMHQQSQRLAQRRMSNMNGGPGSGGAMASTSSNDQNININSLNNTNTGMNNMNNMNNMDKLSRPSTGQMNMQNQQMQQQQAAFKNNSNKNDQYTMSNSMGMQRPQSRQSQTTPMMKQQQMSNQSNLNIAGPNPGNQQQQQTLGKMPNFQITPQDMMEYQAQALAYLSRAQQDGKIPPNLDNNAKQNFIRKYIYHQKATAWRNEQLKAAQSKGNGSAQLNVGPQRTPQQSLMGQGGFPSQPSQQQNQPQQQVMGGLQSMGQPQQSPMMGNMQQPNAASMMNQGNNQPLFSPVMQQKFPMQGQQVNLGNVNAPSNQIRRPQGVPPITDEMKMKLRSLFDEVARGDSFQSKNHTTSLSDQDKLRMKDLMVKINQQYANVDSVLSYYYVLTSDIGGTKKLIQMKFMSRNIIESYQKGIYLANPEILEKLIVHFQRYFDVVKKELTARRQQQQQQQQQQQPQKIDSTQPQMSAAQQRPAMNQPTAQMTGQRPMQPLPQGDQRFMPQNASQGAQNYMPSGMGQLPNMASQSQAQQVPPVPPQQQSQPQQQLSNQRSMGVQQPSQQQFTRNATYGQISQNQPDWSKAVNPEQRGAQPSPQMQSQPVPKNTAKGKKASTSGTAGRRKSTKASGTMPTPGNSAPTPATLANAIKTPNSMPTPQVIQSNSNKGTPIDVSPNSDNKGANVTSKEPIVGEVFGANKVDSKLDSRRELSKTDPEQFFFAALSNLLEVDKADSTNGTKGGSAGTDHTKSPLSPNSAEWTCAVKPEAIKSAFCQVDCIKELTAMEILEECAKMVDRDAKKREEVNSRKREREEPDDIDILFNDTDAKKIKSEDFDRFMFEPVEFDEWKNWLTGLQQAKV
Length1150
PositionTail
OrganismCandida auris (Yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora> Clavispora/Candida clade.
Aromaticity0.05
Grand average of hydropathy-1.026
Instability index61.82
Isoelectric point9.71
Molecular weight128502.55
Publications
PubMed=27988485

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16402
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             8|     562.34|      73|      73|      95|     167|       1
---------------------------------------------------------------------------
   76-  161 (124.75/31.56)	QMRGSLrnnsgtgmqqpqnPQ...NA.QNVQN......QQFSAHARQAQ....AHQ......QQ.QQQQQQ.....Q.........Q..QHQQQQ....IP........GQ.....QNIG.LGLGTDAANQGMNFFPQNQM
  162-  236 (88.20/19.74)	QMRNGM............mPQ...SS.P..........QQGHQQVPQAQmnraAPQ......QQmPQQQQQ.....Q.........Q..QHQQQQnsssGP.........Q.....QGSGpQGINRNIGNQ...LTPQ.QI
  339-  395 (69.56/13.71)	NNTNT................gmnNM.NNMNN......MDKLSRPSTGQ....MNM......QN.QQMQQQ.....Q.........A..AFKN........................N.......SNKNDQ...YTMSNSM
  396-  466 (50.13/ 7.43)	....GM......qrpqsrqSQ...TT.PMMKQ......QQMSNQSNLNI....AGP......NP.GNQQQQ.....Q.........TlgKMPNFQ....IT........PQdmmeyQ............AQALAYLSRAQ.
  467-  525 (61.76/11.19)	..QDGK............iPP...NL.DNNAK......QNF...IRKYI....YHQ......KA.TAWRNE.....Q.........L..KAAQSK...........................GNGSAQLNVGPQRTPQ.QS
  526-  576 (46.67/ 6.31)	LMGQGG.........fpsqPS.........................Q...............QQ.NQPQQQvmgglQ.........S..MGQPQQ....SP........MM.....GN.....MQQPNAASMMN.......
  577-  624 (52.26/ 8.11)	............................QGNN......QPLFSPVMQQK....FPM......QG.QQVNLG.....N.........V..NAPSNQ....IR........RP.....Q..G.VPPITD............EM
  779-  890 (69.00/13.53)	TGQRPM..qplpqgdqrfmPQ...NAsQGAQNympsgmGQLPNMASQSQ....AQQvppvppQQ.QSQPQQ.....QlsnqrsmgvQ..QPSQQQ....FTrnatygqiSQ.....NQPD.WSKAVNPEQRGAQ..PSPQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      71.46|      16|      16|     928|     943|       2
---------------------------------------------------------------------------
  891-  906 (24.35/10.81)	QSQPVPKNT.AKGKK.AS
  928-  943 (26.84/12.70)	NSAPTPATL.ANAIK.TP
  944-  961 (20.27/ 7.71)	NSMPTPQVIqSNSNKgTP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      71.26|      25|      30|    1052|    1078|       3
---------------------------------------------------------------------------
 1052- 1078 (38.28/34.94)	CA..VKPEAIKSAfcQVDCIK....ELTAMEIL
 1081- 1111 (32.98/21.50)	CAkmVDRDAKKRE..EVNSRKrereEPDDIDIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.22|      24|      31|     989|    1015|       5
---------------------------------------------------------------------------
  989- 1015 (33.30/31.30)	NKVDSKLDSRRELSKTDPEQfffAALS
 1021- 1044 (40.92/27.31)	DKADSTNGTKGGSAGTDHTK...SPLS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      80.34|      26|      30|     248|     276|       7
---------------------------------------------------------------------------
  248-  276 (42.63/37.88)	IPPVFLNKIPNLPpnvNTWARI......YDLAQKK
  278-  309 (37.70/24.02)	IPSSSLPAIKEVH...NAHLSIvmhqqsQRLAQRR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16402 with Med15 domain of Kingdom Fungi


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AWRNEQLKAAQSKGNGSAQLNVGPQRTPQQSLMGQGGFPSQPSQQQNQPQQQVMGGLQSMGQPQQSPMMGNMQQPNAASMMNQGNNQPLFSPVMQQKF
2) DKADSTNGTKGGSAGTDHTKSPLSPNSAEW
3) LNQIKQKVHQMRGSLRNNSGTGMQQPQNPQNAQNVQNQQFSAHARQAQAHQQQQQQQQQQQQHQQQQIPGQQNIGLGLGTDAANQGMNFFPQNQMQMRNGMMPQSSPQQGHQQVPQAQMNRAAPQQQMPQQQQQQQQHQQQQNSSSGPQQGSGPQGINRNIGNQLTPQQIQQLSAMIK
4) LTARRQQQQQQQQQQQPQKIDSTQPQMSAAQQRPAMNQPTAQMTGQRPMQPLPQGDQRFMPQNASQGAQNYMPSGMGQLPNMASQSQAQQVPPVPPQQQSQPQQQLSNQRSMGVQQPSQQQFTRNATYGQISQNQPDWSKAVNPEQRGAQPSPQMQSQPVPKNTAKGKKASTSGTAGRRKSTKASGTMPTPGNSAPTPATLANAIKTPNSMPTPQVIQSNSNKGTPIDVSPNSDNKGANVTSKEPIVGEVFGANKVDSKLDSRRELS
5) MQGQQVNLGNVNAPSNQIRRPQGVPPITDEM
6) QAQALAYLSRAQQDGKIPPNLDNNAKQNFI
7) VIPSSSLPAIKEVHNAHLSIVMHQQSQRLAQRRMSNMNGGPGSGGAMASTSSNDQNININSLNNTNTGMNNMNNMNNMDKLSRPSTGQMNMQNQQMQQQQAAFKNNSNKNDQYTMSNSMGMQRPQSRQSQTTPMMKQQQMSNQSNLNIAGPNPGNQQQQQTLGKMPNFQITPQDMME
495
1021
67
736
594
455
277
592
1050
244
1002
624
484
453










Molecular Recognition Features






MoRF SequenceStartStop




1) IRKYIY
484
489