Description | Mediator of RNA polymerase II transcription subunit 10 |
Sequence | MATSEIAQTDENEPLQSTAAQLSALIESTIELGVLVHDNQGTQQSHAALTHRTNQIISQLSGLTNSPFTQQFPVPVDVITYIEDGRNPDIYTREFVEVTAKTNARLKGKMLGFQKLCEVLGDKLVEEFPRLEEGVKDIRRRTSLDSEK |
Length | 148 |
Position | Middle |
Organism | Candida auris (Yeast) |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora> Clavispora/Candida clade. |
Aromaticity | 0.05 |
Grand average of hydropathy | -0.450 |
Instability index | 53.61 |
Isoelectric point | 4.95 |
Molecular weight | 16498.33 |
Publications | PubMed=27988485 |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364146 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP16399 No repeats found |
MoRF Sequence | Start | Stop |
1) PFTQQFPVPVDVITYI 2) TREFV | 67 92 | 82 96 |
© 2021 Shailesh Lab
Designed by Dr. Shailesh Lab & Dr. Jitendra K. Thakur Lab