<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16396

Description Uncharacterized protein
SequenceMTEAKPKSTKVAGGPRPSHPTTIKDSIMAMKYDMPRPATSVYPLDDKLSKKTYPDYCPWEDGEDSSQKLENSGYLNKGFFESSKVSNEYYSARNLIQETLFSSSQNCNKILRELSQHLTSSYKARDDSINTIRACSYAFRLPPRVTLTASKKDAWLKDLADPNVPLHIVSAKIPHGIRNKVLVDAMCSRNIPIPRAIWFTKCTLYSEIISMKKKSHVKNNSGSQSGIGQSVCSLQIIERRWLREWTQQVADYMLKFSREIGALTSHEAKTSYKERMDYLIAYVSAVYIEDLVDKPYFLSLVLRLLKEDHHVGSIKVSDLFELVKCEPEEEEDTVLRSLGGQSYDVGQILLALSLVKIFWKDIMLEDFLCKHLADALLLNYLIISKLPVNSKRVSRICVLSSQVKSESLSFIRGMIVELFLKKSDSFIIPSSWTVLGDVLLSIIRDSDVYSDETQRDVLERALVLMDFRNESLVVHSHDSCGERTTVTDMTQEAESSIERQYALFNRSSDDVLKLVEQLDRHKFKHTFPFSLLPSLSECRSSDGRNIRLYAVISWCVSSFRDMGLAKERILIVCNSIKAIITQQKGKNSTSIRNSLENDILECIFNLVEIPPTQLRFKNLYVLFNELYQLKVITISAYLRKLIASGIFYSSPKTSNLNEAEEVNEHAKLHLLLLKNLPVLNNRQCDRILKKWTENDLNFSEIFSNTTRMLREDNLDKILKNECEEFQHILRHIEGLSTGLQFLVINWFTSELKAFISKSSRLVHISPPIIARLYTLYASTCNLTAFFKVFVRFLLKNENKIIIFYMDTLYLLGKLILRHTGLLESLADGSVCATSTFSEILSLFLQAYKDLLSRESDMFDFRPLWILICRRLQRTPEQQHFQSSDPIKKGSYVYGFDQRATSMTLKSPVNDEDIHSADLTLHEVEMLASRDLMPLKEIELGDIVAEIKEECSCVVEIMKMNSLNAKVRALLELASFGPHEVSQLHLYKLLEHLRRLTLKSDPELVTHEFVKVLKDVLESKCEKRVSSLMTFVIAFEIVTIHSLFQLLDGFDSDILTLNVPQAKKIILSKLTSLDSGDYLLSVLLSLAFFEFKTKHHAILLKFIIDEHSRSKELSFIEEDSVYDLIVLEPKRTVDYMCGRLGKEKSCVILSTLLKVSPPVITIDDIGRLSDKINEFNLPMVQGMLSLLTSKDCDLKAVLDSIIKGSKSYLTVDNSYFGELFNLCHWNVRLEIFKQMENIFFNHLSSSMSSSSNIVYDARLSMLNDFFKKFRINSQEKIETSAAHFDELLKCLKYIVQKVDCSGKTTDKMGELSGEISTYLRIVIIRIETLTEVMSNSYSNSFEFLTLLVSLLNSEVISTTDERLRILLYDLLHTLRTSFMQQFMFRDNDDEVLNNAPSDNQVKLSKVSRTAPSIATDKVEQNDVKEKLAKAFAVLDIRDPVVVKHVGPEESFRYYADCASTLDEDELRSDGDVNILNQKNLFLCSKGHPSAFDSPFGEMHRHNVVRLPFAIKSFQLIENTGVGINDGCVNLALFRAYTTKENEP
Length1542
PositionKinase
OrganismCandida auris (Yeast)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Saccharomycotina> Saccharomycetes> Saccharomycetales> Metschnikowiaceae> Clavispora> Clavispora/Candida clade.
Aromaticity0.09
Grand average of hydropathy-0.132
Instability index44.99
Isoelectric point6.39
Molecular weight176146.11
Publications
PubMed=27988485

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16396
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      76.92|      18|     153|     606|     623|       2
---------------------------------------------------------------------------
  606-  623 (32.64/24.52)	LVEI.PPTQLRF....KNLYVLF
  761-  776 (22.29/13.97)	LVHIsPPIIAR.......LYTLY
  782-  803 (21.99/13.65)	LTAF.FKVFVRFllknENKIIIF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     219.50|      77|     673|     634|     726|       3
---------------------------------------------------------------------------
  634-  726 (103.05/108.71)	ISAYLRKLIASgIFYSSPKTSNlneaEEVNEHAKLHLL..LLkNLPVLNNR.QCDRILKkwteNDL......NFSEIFsnttrMLReDNLDKILKNECEEFQ
 1314- 1399 (116.45/75.18)	ISTYLRIVIIR.IETLTEVMSN....SYSNSFEFLTLLvsLL.NSEVISTTdERLRILL....YDLlhtlrtSFMQQF.....MFR.DNDDEVLNNAPSDNQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     179.40|      57|     665|     309|     476|       4
---------------------------------------------------------------------------
  374-  432 (90.73/221.17)	DAL.LLNYLIISKLP.VNSKRVSRICVLSSqvKSESLSFIRGMIVELFLKKSDSFIIPSSW
  806-  864 (88.67/19.99)	DTLyLLGKLILRHTGlLESLADGSVCATST..FSEILSLFLQAYKDLLSRESDMFDFRPLW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      96.76|      33|     669|     440|     476|       5
---------------------------------------------------------------------------
  440-  476 (47.24/47.91)	LSIIRDSDVYsDETqrdVLE..RALVLMDFR...NESLVVHS
 1112- 1149 (49.51/35.01)	LSFIEEDSVY.DLI...VLEpkRTVDYMCGRlgkEKSCVILS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.47|      44|     276|    1190|    1236|       6
---------------------------------------------------------------------------
 1190- 1236 (71.11/67.09)	DCDLKaVLD..SIIKGSKSYLTVDNSYFGELFNlcHWNVRLEI....FKQMEN
 1468- 1517 (72.36/54.62)	DGDVN.ILNqkNLFLCSKGHPSAFDSPFGEMHR..HNVVRLPFaiksFQLIEN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.80|      15|     679|     315|     329|       8
---------------------------------------------------------------------------
  315-  329 (26.08/16.09)	KVSDLFELVKCEPEE
  965-  979 (24.72/14.82)	KVRALLELASFGPHE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16396 with Med12 domain of Kingdom Fungi
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