<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16378

Description Serine/threonine protein kinase
SequenceMRVFSQEAGKNNRRKALSDHLPEYPSSPAIMATLQTHPRRPAEEFLSGFSPAATFQHGFGGSVPPESAAGGGVTVHVAVGKSVEKAVALLQWTFSTFPGQDICLLHVHRPSPLIPTLLGKLPASRANPETVATFRNQETEETRKLLHTYLMTCSRSRVKASVITTERDEVQKGIVDLVNLHNVKKLVVGAIPDFLKGRKSSSKTCHVAKYAPSYCEMWFVDKGKLIWTRQAFATTPTHNLRSCSLNSGESEVIVRHKDKDSCSSSGRDENWVPAEASQAEITSSSVSQCDPLYSDSVSSSTYATPAEPSLSSVSSAKTMEECLSVQLAELRREVDESKDEAYIKLLEQKQAEAEAMEAFNMVKALETALSREVKLRGEAEDALRTTLQCQENLLQEREKSNQQLQKTMRNIAVLDSRAQEANRRREEVAGELKLIQASIAALRKEKQKLQRQKIEATRWLDRWRSREQCEDAGESKFMGLMADISQLPEFLLSDLEAATCNFSENFRIGQGGCGVVYKGELLDKTVAIKKLHSYNMQRQREFDNAVQVLNKLHHPRLVKLIGVCPDSWLLVYEYLPGGSIQNLFNNNSISALNWKIRSRIVADIASGLLFLHSSMPKKIVHGNLKPENLLLDSENRCRISDYGDHMLMSSQNFRCPSFRRCSSSTGVSLHIDPDSHRTGTLTHKSDIYSLGVIILELVTGKTHGGLIGQVRRALSNGKVTSILDSSAGEWPTYVARRLVELGLQCCESNSRARPELTPSLVKELEHMPFLEEQTIPSFFLCPILREIMHDPHVAADGFTYEGEALLGWLGNGRETSPMTNLRLSHLNLTPNHSLRLAIQDWLANLEIAECS
Length851
PositionTail
OrganismHandroanthus impetiginosus
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Lamiales> Bignoniaceae> Crescentiina> Tabebuia alliance> Handroanthus.
Aromaticity0.06
Grand average of hydropathy-0.373
Instability index51.27
Isoelectric point7.57
Molecular weight94829.86
Publications
PubMed=29253216

Function

Annotated function Functions as an E3 ubiquitin ligase.
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:InterPro
protein serine kinase activity	GO:0106310	IEA:UniProtKB-EC
protein threonine kinase activity	GO:0106311	IEA:UniProtKB-EC
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP16378
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      45.42|      14|      88|     150|     169|       1
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  124-  137 (23.74/16.88)	SRANPETVATFRNQ
  156-  169 (21.68/ 6.42)	SRVKASVITTERDE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     166.52|      49|     132|     454|     504|       2
---------------------------------------------------------------------------
  356-  406 (56.71/36.15)	MEAfnmVKALE.TA....LSREvklrgEAEDALRTTL........QCQENLLQEREKSNQQLQK
  408-  442 (27.07/13.31)	MRN...IAVLDsRAqeanRRRE.......EVAGELKL..IQASIAAL.................
  454-  504 (82.75/63.36)	IEA...TRWLD.RW....RSRE.....QCEDAGESKFmgLMADISQLPEFLLSDLEAATCNFSE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.70|      28|     516|      23|      63|       3
---------------------------------------------------------------------------
   24-   56 (42.02/53.34)	YPSSPAiMATLQThprrPAEEFLSGFSPAATFQ
  293-  320 (48.67/21.42)	YSDSVS.SSTYAT....PAEPSLSSVSSAKTME
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP16378 with Med32 domain of Kingdom Viridiplantae

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