<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP16346

Description Serine/threonine protein kinase
SequenceMGEKSMNKVEGLDELPPPADLVAAVAITGSKKNKHVVKWALEKFVPEGIVYFKLLHVRPVISRIPTPMGNHIPISQVREDIAAAFRKEVEWQVTEKLLPYKMMCTQRKVQVEIVQIESDDVVTGIAGDIRKHKITKLVIGASSRRIFSRSRTMSSRISECCPTFCTVYAVSKGKLSSLRPSDSETNECCRDDSSDTSCSTDNSSSHIASSQTDWTDRGSIGSFSRFRSDSLPVQRLQALSTINQTLFDKNMPLSGIVHSGNLSVDTVQRSYGNRNDTTSYASSFMSSVADNPSFNEASTSGASTETRANIDFELEKLRIELRHIRGMYAVAEGEAIHASRKLNELQKCRLEEEINLKQISFKEQEAEDLARQEIRRHEAAKIEAELVKESAEREAAERKEAEIRASRQTKEKERLESVFNGSFYQYRLFTWEEIISATSSFSDNLKIGTGAHGTVYKCSFQHTTAAVKILHAKEANRSRQFQQELEILSKIRHPHLLILLGACPDQSCLVYEFMENGSLEDRLMRKNNTPPLLWFDRFRIAWEVALALVFLHNSKPKAIIHRDLKPANILLGRNYVSKIGDVGLSTMVNEDYLSLSSAYKDTAPVGTLCYIDPEYQRTGVVSAKSDVYAFGMVILQLLTAKPAIALAHKVELAVANDRLMEVLDPEGGAWPIEEAMDLALMALKCTELRRIDRPDLENHILPILEKMKELAENARNLALHSPQAAPKHFICPILNEVMTDPCVAADGYTYERRAIEGWLEEKDTSPITDLPLPHKCLVPNYALLSEIVECKSGKGT
Length796
PositionTail
OrganismHandroanthus impetiginosus
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> lamiids> Lamiales> Bignoniaceae> Crescentiina> Tabebuia alliance> Handroanthus.
Aromaticity0.06
Grand average of hydropathy-0.333
Instability index50.34
Isoelectric point6.36
Molecular weight89220.86
Publications
PubMed=29253216

Function

Annotated function Functions as an E3 ubiquitin ligase. 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW
ubiquitin-protein transferase activity	GO:0004842	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP16346
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     173.42|      54|     311|      26|      90|       1
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   26-   79 (91.32/67.06)	AITGSKKNKHVVKWALEKFVPEGIVYFKLLHVRPVISR.IPTPMGNHIPISQVRE
  335-  389 (81.19/57.81)	AIHASRKLNELQKCRLEEEINLKQISFKEQEAEDLARQeIRRHEAAKIEAELVKE
  403-  416 ( 0.91/12.76)	.IRASRQTKE..KERLE......................................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      75.74|      21|      26|     141|     161|       3
---------------------------------------------------------------------------
  141-  161 (38.13/25.27)	ASSRRIFSRSRTMSSRISECC
  169-  189 (37.61/24.82)	AVSKGKLSSLRPSDSETNECC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     214.52|      68|     135|     496|     570|       6
---------------------------------------------------------------------------
  496-  570 (99.37/95.33)	LLILLGACPDQScLVYEfMENGSLEDRLMRKNNTPPLLWfdrfRIAWEVALALVFLHNSKPKAIIHRDLKpANIL
  634-  701 (115.15/80.21)	ILQLLTAKPAIA.LAHK.VELAVANDRLMEVLDPEGGAW....PIEEAMDLALMALKCTELRRIDRPDLE.NHIL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.85|      28|      87|     193|     220|       7
---------------------------------------------------------------------------
  193-  220 (51.06/38.10)	SSDTSCSTDNSSSHIASSQTDWTD.RGSI
  282-  310 (43.79/31.54)	SSFMSSVADNPSFNEASTSGASTEtRANI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP16346 with Med32 domain of Kingdom Viridiplantae
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